2-[[2-[[2-[[6-amino-2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[2-[[2-[[[1-[2-[[2-[[2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[2-[(2-amino-1-hydroxyethylidene)amino]-1-hydroxy-3-methylpentylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxypropylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxyhexylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1,3-dihydroxybutylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxyethylidene]amino]-4-methylpentanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1-hydroxypropylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxy-3-methylpentylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino]-1-hydroxy-3-methylpentylidene]amino]-1-hydroxyhexylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1-hydroxyhexylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]pentanediimidic acid

• 分子结构分类: 有机化合物 - 有机聚合物 - 多肽
• 英文名称: 2-[[2-[[2-[[6-amino-2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[2-[[2-[[[1-[2-[[2-[[2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[2-[(2-amino-1-hydroxyethylidene)amino]-1-hydroxy-3-methylpentylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxypropylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxyhexylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1,3-dihydroxybutylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxyethylidene]amino]-4-methylpentanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1-hydroxypropylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxy-3-methylpentylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino]-1-hydroxy-3-methylpentylidene]amino]-1-hydroxyhexylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1-hydroxyhexylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]pentanediimidic acid
• 化学式: C₁₃₁H₂₂₉N₃₉O₃₁
• 分子量: 2846.5
• InChiKey: VDXZNPDIRNWWCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.2
• 重原子数：
  201
• 可旋转键数：
  99
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  1240
• 氢给体数：
  44
• 氢受体数：
  64

文献信息

• PEPTIDES ANTIMICROBIENS ET LEURS UTILISATIONS
  申请人：Sorbonne Université

  公开号：EP3559025A1

  公开（公告）日：2019-10-30
• CONTACT LENS CARE SOLUTION
  申请人：BenQ Materials Corporation

  公开号：US20170298296A1

  公开（公告）日：2017-10-19

  The invention is related to a contact lens care solution comprising a buffer solution, a chelating agent, a surfactant and a wetting agent, wherein the wetting agent comprises 100 parts by weight of glycerol, 0.5 to 40 parts by weight of vinylacetamide-containing polymer and 5 to 40 parts by weight of alginic acid.
• US9926515B2
  申请人：——

  公开号：US9926515B2

  公开（公告）日：2018-03-27
• [EN] ANTIMICROBIAL PEPTIDES AND USES THEREOF<br/>[FR] PEPTIDES ANTIMICROBIENS ET LEURS UTILISATIONS
  申请人：UNIV SORBONNE

  公开号：WO2018115798A1

  公开（公告）日：2018-06-28

  La présente invention concerne des peptides dotés d'une activité anti-inflammatoire, anti- angiogénique et/ou activité antimicrobienne, un médicament ou une composition pharmaceutique comprenant de tels peptides, et leur utilisation dans la prévention ou le traitement de maladies inflammatoires, et plus particulièrement des maladies inflammatoires dues ou associées à des infections microbiennes, ou dans la prévention ou le traitement de maladies liées à l'angiogenèse.