1-Hexadecanoyl-cyclophosphatidic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 1-Hexadecanoyl-cyclophosphatidic acid
• 英文别名: (2-hydroxy-2-oxo-1,3,2λ5-dioxaphospholan-4-yl)methyl hexadecanoate
• 化学式: C₁₉H₃₇O₆P
• 分子量: 392.5
• InChiKey: WLYRJURLXSFXRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• THERAPEUTIC AGENT FOR DEMYELINATING DISEASE
  申请人：OCHANOMIZU UNIVERSITY

  公开号：US20150352132A1

  公开（公告）日：2015-12-10

  It is an object of the present invention to provide a novel therapeutic agent for demyelinating disease which has an action to suppress demyelination of nerve axons. According to the present invention, a therapeutic agent for demyelinating disease which comprises cyclic phosphatidic acids, carba-cyclic phosphatidic acids, thia-cyclic phosphatidic acids, or a salt thereof is provided.