conduritol B epoxide | 6705-47-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: conduritol B epoxide
• 英文别名: conduritol B-epoxide；Conduritol epoxide；7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
• CAS: 6705-47-1
• 化学式: C₆H₁₀O₅
• 分子量: 162.142
• InChiKey: ZHMWOVGZCINIHW-UHFFFAOYSA-N

物化性质

• 沸点：
  360.5±42.0 °C(Predicted)
• 密度：
  1.925±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  93.4
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
  申请人：ELMALEH David R.

  公开号：US20160263257A1

  公开（公告）日：2016-09-15

  Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula; wherein X is OH, C 1 -C 6 alkoxyl; Y and Z are independently selected from a C 1 -C 6 alkyl, C 1 -C 6 alkoxyl, halogen, mi-substituted or C 1 -C 6 substituted amine, 18 F, 19 F, or H; and n is 1, 2, or 3; and wherein for structure (I), if n are both 1 and Y and Z are both H and X is OH.

  揭示了作为检测动脉粥样硬化斑块和治疗动脉硬化和阿尔茨海默病的成像剂的新型克罗莫林类似物以及制备克罗莫林类似物的方法。克罗莫林类似物具有一般式;其中X为OH，C1-C6烷氧基; Y和Z分别选自C1-C6烷基，C1-C6烷氧基，卤素，mi-取代或C1-C6取代胺，18F，19F或H; n为1，2或3;对于结构（I），如果n都为1且Y和Z都为H且X为OH。
• THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY
  申请人：Yupo Corporation

  公开号：EP1172400A1

  公开（公告）日：2002-01-16

  Described is a thermoplastic resin film having on a surface thereof a hydroxy-modified imine polymer containing repeating units represented by the following general formula (I) in an amount of 5 mol% or more based on the total of repeating units. This thermoplastic resin film has ink transfer, adhesion and aging stability, and excellent printability of generating no back ghost when offset printing using oxidation polymerization type ink is performed on both faces.

  所述的是一种热塑性树脂薄膜，其表面含有羟基改性亚胺聚合物，该聚合物含有以下通式 (I) 所代表的重复单元，其含量为重复单元总量的 5 mol% 或以上。这种热塑性树脂薄膜具有油墨转移性、附着性和老化稳定性，而且在使用氧化聚合型油墨进行胶版印刷时，两面都不会产生重影，具有极佳的印刷适性。
• Thermoplastic resin film satisfactory in printability
  申请人：YUPO CORPORATION

  公开号：US20020054991A1

  公开（公告）日：2002-05-09

  Described is a thermoplastic resin film having on a surface thereof a hydroxy-modified imine polymer containing repeating units represented by the following general formula (I) in an amount of 5 mol % or more based on the total of repeating units. This thermoplastic resin film has ink transfer, adhesion and aging stability, and excellent printability of generating no back ghost when offset printing using oxidation polymerization type ink is performed on both faces 1 .

  所述热塑性树脂薄膜的表面含有羟基改性亚胺聚合物，该聚合物含有以下通式 (I) 所代表的重复单元，其含量为重复单元总量的 5 mol % 或以上。这种热塑性树脂薄膜具有油墨转移性、附着性和老化稳定性，并且在使用氧化聚合型油墨进行胶版印刷时，两面都不会产生重影，具有优异的印刷适性。 1 .
• Novel therapy for lysosomal enzyme deficiencies
  申请人：Ginns I. Edward

  公开号：US20060083718A1

  公开（公告）日：2006-04-20

  The present invention provides a therapeutic delivery system comprising an extracted yeast cell wall comprising beta-glucan, a payload trapping molecule and a payload molecule, wherein the payload molecule and the payload trapping molecule are soluble in the same solvent system wherein the payload molecule supplements the function of the deficient lysosomal enzyme. The invention further provides methods of making and methods of using the therapeutic delivery system.

  本发明提供了一种治疗递送系统，该系统包括提取的包含β-葡聚糖的酵母细胞壁、有效载荷捕获分子和有效载荷分子，其中有效载荷分子和有效载荷捕获分子可溶于同一溶剂系统，其中有效载荷分子可补充缺乏的溶酶体酶的功能。本发明进一步提供了治疗递送系统的制造方法和使用方法。
• COMPOSITIONS AND THEIR USES FOR LYSOSOMAL ENZYME DEFICIENCIES
  申请人：University of Massachusetts

  公开号：EP1802289A2

  公开（公告）日：2007-07-04