Diaminomethylidene(diethyl)azanium;sulfate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: Diaminomethylidene(diethyl)azanium;sulfate
• 英文别名: diaminomethylidene(diethyl)azanium;sulfate
• 化学式: C10H28N6O4S
• 分子量: 328.44
• InChiKey: VZAFCEFGYOMBML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.21
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  189
• 氢给体数：
  6
• 氢受体数：
  6

文献信息

• Novel phenanthridines
  申请人：Flockerzi Dieter

  公开号：US20060116518A1

  公开（公告）日：2006-06-01

  Compounds of a certain formula 1, in which R1, R2, R3, R31, R4, R5, R51, R6 and R7 have the meanings indicated in the description, are novel effective PDE4 inhibitors.

  某种化学式为1的化合物，其中R1、R2、R3、R31、R4、R5、R51、R6和R7的意义如说明中所示，是一种新的有效PDE4抑制剂。
• Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines
  申请人：Peters Jörg

  公开号：US20050014933A1

  公开（公告）日：2005-01-20

  A method for renaturation of proteins comprising adding to a solution of denatured, chemically modified or reduced proteins a refolding buffer containing a primary, secondary or tertiary amine. Said method has been applied, for example, to interleukin-4 and bovine pancreatic trypsin inhibitor (BPTI), wich were previously (i) solubilized in the presence of guanidinium hydrochloride as chaotronic agent, and (ii) subjected to sulfitolysis.

  一种蛋白质复性的方法，包括向变性、化学修饰或还原蛋白质溶液中加入含有伯胺、仲胺或叔胺的复性缓冲液。例如，上述方法已应用于白细胞介素-4 和牛胰蛋白酶抑制剂（BPTI），它们之前(i) 在作为混沌剂的盐酸胍的存在下溶解，(ii) 经过亚硫酰水解。
• BICYCLIC ANSAMYCINS AND THEIR USE AS ANTITUMOR AGENTS
  申请人：PFIZER INC.

  公开号：EP0693073A1

  公开（公告）日：1996-01-24
• PROCESS FOR RENATURATION OF RECOMBINANT, DISULFIDE CONTAINING PROTEINS AT HIGH PROTEIN CONCENTRATIONS IN THE PRESENCE OF AMINES
  申请人：Bayer Schering Pharma Aktiengesellschaft

  公开号：EP1453858B1

  公开（公告）日：2011-01-12
• US5387584A
  申请人：——

  公开号：US5387584A

  公开（公告）日：1995-02-07