2-Ethyl-3-methyl-4-oxobutanenitrile | 88456-20-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-Ethyl-3-methyl-4-oxobutanenitrile
• CAS: 88456-20-6
• 化学式: C₇H₁₁NO
• 分子量: 125.17
• InChiKey: AWLZGCPKHIHYMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  40.9
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Verfahren zur Herstellung von 3-Cyan-2-alkylalkanalen und die Verwendung von 3-Cyan-2-ethylhexanal zur Herstellung von 2-Propylpentansäure
  申请人：BASF Aktiengesellschaft

  公开号：EP0087712A1

  公开（公告）日：1983-09-07

  Verfahren zur Herstellung von 3-Cyanaldehyden der Formel l in der R' und RZ C,- bis C6-Alkylreste und R3 ein Wasserstoffatom oder einen C1- bis C3-Alkylrest bedeuten, durch Reaktion einer Mischung eines Aldehyds der Formel II mit wasserfreier Blausäure in Gegenwart eines basischen Katalysators in einem Lösungsmittel sowie die Verwendung von 3-Cyan-2-ethylhexanal zur Darstellung von 2-Propylpentansäure.

  一种制备式 I 的 3-氰基醛的工艺 其中 R' 和 RZ 为 C，- 至 C6-烷基，R3 为氢原子或 C1-至 C3-烷基的一种制备式 I 的 3-氰基醛的工艺。 在碱性催化剂存在下，在溶剂中与无水氢氰酸反应，并使用 3-氰基-2-乙基己醛制备 2-丙基戊酸。
• Reductive amination of carbonylnitriles and similar compounds
  申请人：UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC.

  公开号：EP0394967A1

  公开（公告）日：1990-10-31

  Carbonylnitriles and iminonitriles are subjected to reductive amination in two steps, the first of which is at a temperature sufficient to produce the aminonitrile and the second of which is at a higher temperature and/or uses hydrogenation catalyst more reactive toward nitrile groups sufficient to produce the hydrogenated compound. The processes may be conducted under lower pressures, e.g., under about 700 psig, while maintaining desirable selectivity to the aminated product.

  羰基腈和亚氨基腈分两步进行还原胺化，第一步的温度足以生产氨基腈，第二步的温度更高，和/或使用对腈基反应更强的氢化催化剂，足以生产氢化化合物。这些过程可以在较低的压力下进行，例如在约 700 psig 的压力下，同时保持对胺化产物的理想选择性。
• Amination of carbonyls
  申请人：UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC.

  公开号：EP0394968A1

  公开（公告）日：1990-10-31

  Organic compounds containing at least one carbonyl group are reductively aminated to minimize the formation of hydroxylated side product by the use of at least one of (i) an amination promoter, (ii) water removal, (iii) lower hydrogen partial pressure during the formation of an imine or enamine intermediate or (iv) primary or secondary amine reactant to form an imine or enamine intermediate.

  对含有至少一个羰基的有机化合物进行还原胺化，以尽量减少羟基化副产物的形成，方法是使用以下至少一种：(i)胺化促进剂；(ii)脱水；(iii)在形成亚胺或烯胺中间体的过程中降低氢分压；或(iv)使用伯胺或仲胺反应物形成亚胺或烯胺中间体。
• Fluorescent naphthalene -1,4,5,8-tetracarboxylic bisimides with an electron-donating substituent on the nucleus
  申请人：——

  公开号：US20030153005A1

  公开（公告）日：2003-08-14

  Naphthalene-1,4,5,8-tetracarboxylic bisimides of the general formula I 1 where the variables are defined as follows: R 1 and R 2 independently of one another are hydrogen, substituted or unsubstituted alkyl or substituted or unsubstituted aryl; X and Y independently of one another are halogen, amino or a radical with the formula —NHR 3 , —OR 3 , where R 3 has the formula —CH 2 R 4 , —CHR 4 R 5 , or —CR 4 R 5 R 6 , where R 4 , R 5 , and R 6 independently of one another are hydrogen, substituted or unsubstituted alkyl, aryl, alkoxy, alkylthio, aryloxy or arylthio, and at least one of the two substituents X and Y is other than halogen, their preparation and use as fluorescent dyes, for coloring high molecular mass organic materials and inorganic materials, as laser dyes, and also for fluorescence marking and as fluorescent labels for biomolecules.
• US4532082A
  申请人：——

  公开号：US4532082A

  公开（公告）日：1985-07-30