4-Methyl-2-{[1-naphthalen-1-yl-meth-(E)-ylidene]-amino}-phenol | 878193-89-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-Methyl-2-{[1-naphthalen-1-yl-meth-(E)-ylidene]-amino}-phenol
• CAS: 878193-89-6
• 化学式: C₁₈H₁₅NO
• 分子量: 261.323
• InChiKey: JLJRJSRPGQMKDQ-XDHOZWIPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  20.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  32.59
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  4-Methyl-2-{[1-naphthalen-1-yl-meth-(E)-ylidene]-amino}-phenol 、 ((E)-1,3-Dimethoxy-buta-1,3-dienyloxy)-trimethyl-silane 在 (R)-BINOL based chiral phosphoric acid pyridinium salt 、 苯甲酸 作用下， 以 均三甲苯 为溶剂， 反应 12.0h， 以79%的产率得到(6R)-N-(2-hydroxy-5-methylphenyl)-4-methoxy-6-(1-naphthyl)-3,4-didehydropiperidin-2-one
  参考文献：
  名称：

  手性布朗斯台德酸催化Brassard's二烯与亚胺的对映选择性aza-Diels-Alder反应。

  摘要：

  DOI：

  10.1002/anie.200601345
• 作为产物：
  描述：

  1-萘甲醛 、 邻氨基对甲苯酚 生成 4-Methyl-2-{[1-naphthalen-1-yl-meth-(E)-ylidene]-amino}-phenol
  参考文献：
  名称：

  Mechanism of oil-in-water emulsification using a water-soluble amphiphilic polymer and lipophilic surfactant

  摘要：

  A new O/W (oil-in-water) emulsification system was developed using the amphiphilic polymer HHM-HEC (hydrophobically-hydrophilically modified hydroxyethyl cellulose) and a lipophilic surfactant. HHM-HEC was used as a thickener and polymeric surfactant, and the addition of small quantities of various types of nonionic lipophilic surfactant (hydrophilic-lipophilic balance < 5) decreased the droplet size of several types of oil due to a lowering of the tension at the water/oil interface. The oil droplets were held by the strong network structure of the aqueous HHM-HEC solution, preserving the O/W phase without inversion. These stable O/W emulsions were prepared without the addition of hydrophilic surfactants and thus show improved water repellency. (c) 2006 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.jcis.2006.03.066

文献信息

• Mechanism of oil-in-water emulsification using a water-soluble amphiphilic polymer and lipophilic surfactant
  作者：Eri Akiyama、Akio Kashimoto、Hajime Hotta、Tomohito Kitsuki

  DOI：10.1016/j.jcis.2006.03.066

  日期：2006.8

  A new O/W (oil-in-water) emulsification system was developed using the amphiphilic polymer HHM-HEC (hydrophobically-hydrophilically modified hydroxyethyl cellulose) and a lipophilic surfactant. HHM-HEC was used as a thickener and polymeric surfactant, and the addition of small quantities of various types of nonionic lipophilic surfactant (hydrophilic-lipophilic balance < 5) decreased the droplet size of several types of oil due to a lowering of the tension at the water/oil interface. The oil droplets were held by the strong network structure of the aqueous HHM-HEC solution, preserving the O/W phase without inversion. These stable O/W emulsions were prepared without the addition of hydrophilic surfactants and thus show improved water repellency. (c) 2006 Elsevier Inc. All rights reserved.
• Chiral Brønsted Acid Catalyzed Enantioselective Aza-Diels–Alder Reaction of Brassard's Diene with Imines
  作者：Junji Itoh、Kohei Fuchibe、Takahiko Akiyama

  DOI：10.1002/anie.200601345

  日期：2006.7.17