Acryloylcholine | 20284-80-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Acryloylcholine
• 英文别名: trimethyl(2-prop-2-enoyloxyethyl)azanium
• CAS: 20284-80-4
• 化学式: C8H16NO2+
• 分子量: 158.22
• InChiKey: AIUAMYPYEUQVEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  、 氯甲烷 、 丙烯酸二甲胺基乙酯 、 4-甲氧基苯酚 、 丙-2-烯酸酯 、 Water acrylate 、 氧气 、 Acryloylcholine 在 水 、 final product 作用下， 以 水 为溶剂， 反应 4.33h， 生成 丙烯酰氧乙基三甲基氯化铵
  参考文献：
  名称：

  Quaternization process

  摘要：

  制备不饱和季铵盐水溶液的过程，对应以下公式：H.sub.2 C=C(R.sub.3)--C(O)--A--R.sub.4 --N.sup.+ (R.sub.1)(R.sub.2)(R)X.sup.-

  公开号：

  US05260480A1

文献信息

• Use of functionalized onium salts as a soluble support for organic synthesis
  申请人：Vaultier Michel

  公开号：US20070043234A1

  公开（公告）日：2007-02-22

  The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A 1 + , X 1 − , wherein A 1 + represents a cation and X 1 − represents an anion.

  该发明涉及使用至少一个有机功能官能化的离子盐作为可溶性支持体，在至少一个有机溶剂的存在下，用于在均相相中通过至少一个所述有机功能的转化对分子进行有机合成。该离子盐使合成的分子能够被释放。该离子盐在室温下以液态或固态形式存在，符合以下公式A1+，X1−，其中A1+代表阳离子，X1−代表阴离子。
• [EN] FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME<br/>[FR] POLYMERSOMES ET NANORÉACTEURS SENSIBLES À LA FORCE; PROCÉDÉS LES UTILISANT
  申请人：ADOLPHE MERKLE INSTITUTE UNIV OF FRIBOURG

  公开号：WO2019034597A1

  公开（公告）日：2019-02-21

  The mechanically induced melting properties of DNA were employed to achieve force labile membranes is described. Nucleobase pairs were used as mechanophores. Adenine and thymine functionalized complementary amphiphilic block copolymers were self-assembled into polymersomes. The nucleobases formed hydrogen bonds which were disrupted upon force stimulation. The exposure of the disconnected nucleobases to the hydrophobic matrix of the membranes lead to a change of permeability which permitted the exchange of water-soluble molecules throughout the polymer matrix. Moreover, the encapsulation of horseradish peroxidase enabled the reaction of luminol with hydrogen peroxide to yield a luminescence producing species similar to the marine bioluminescence. Moreover, the same nano-reactors were employed to catalyze the formation of a polyacrylamide gel when force was applied. Insights into the change of permeability of supramolecular networks upon force are provided. These systems are useful for drug delivery, as nanoreactors and for the selective release of curing agents for 3D printing, or fragrances.

  DNA的机械诱导熔化特性被用来实现易受力破裂的膜。核碱基对被用作机械感受器。腺嘌呤和胸腺嘧啶功能化的互补两性分块共聚物自组装成聚合体囊。核碱基形成氢键，在受力刺激下被破坏。断开的核碱基暴露在膜的疏水基质中，导致渗透性的改变，从而允许水溶性分子在聚合物基质中交换。此外，封装辣根过氧化物酶使得辣根酰胺与过氧化氢反应产生类似海洋生物发光的发光物种。此外，当施加力时，相同的纳米反应器被用来催化聚丙烯酰胺凝胶的形成。提供了关于受力下超分子网络渗透性变化的见解。这些系统可用于药物传递、纳米反应器以及用于3D打印的固化剂或香料的选择性释放。
• METHOD FOR PREPARING A BIOCIDAL, BACTERIOCIDAL AND/OR BACTERIOSTATIC MATERIAL
  申请人：COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA)

  公开号：US20220053766A1

  公开（公告）日：2022-02-24

  A process for preparing a biocidal, bactericidal and/or bacteriostatic material including the preparation of a polymer precursor solution that has (a) at least one monomer A having a porphyrin group and at least one radical polymerizable function, (b) at least one radical polymerizable monomer B, a photoinitiator, and (c) at least one of the monomers chosen from a monomer C having a quaternary amine and a radical polymerizable function; and/or a monomer D having copper and a radical polymerizable function. Also, the material obtainable by the process and its uses.

  一种制备生物杀菌、杀菌和/或抑菌材料的方法，包括制备具有（a）至少一种具有卟啉基团和至少一种自由基聚合功能的单体A的聚合物前体溶液，（b）至少一种自由基聚合单体B，光引发剂，以及（c）至少一种从具有季铵盐基团和自由基聚合功能的单体C中选择的单体; 和/或具有铜和自由基聚合功能的单体D。此外，还包括所述方法获得的材料及其用途。
• Particles for electrophoretic displays
  申请人：Merck Patent GmbH

  公开号：US10106686B2

  公开（公告）日：2018-10-23

  This invention relates to particles comprising a pigment core particle encapsulated by a polymer, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.

  这项发明涉及由聚合物封装的颜料核心颗粒组成的颗粒，其制备方法，包含这种颗粒的电泳流体，以及包含这种流体的电泳显示设备。
• FERMENTED FOOD EXTRACT COMPOSITION
  申请人：Shinshu University

  公开号：US20170182108A1

  公开（公告）日：2017-06-29

  Provided is a fermented food extract that has a blood pressure-lowering action and is useful as a functional health food or pharmaceutical composition. This fermented food extract is obtained by: subjecting a fermented food, preferably a fermented fagopyrum esculentum lyophilisate, to acetone extraction; eluting the fermented fagopyrum esculentum acetone extract using a solid phase extract cartridge filled with a resin to which a phenyl group is bonded, with formic acid-containing water used as an eluent; and fractionating and purifying the eluate using a column (PFP column) filled with a carrier to which a pentafluorophenyl group is bonded, with formic acid/methanol-containing water used as a mobile phase. This functional health food or pharmaceutical composition contains said extract or at least a part thereof as an active ingredient.

  提供的是一种具有降血压作用并可用作功能性健康食品或药用组合物的发酵食品提取物。该发酵食品提取物的获取方法包括：将发酵食品（最好是发酵荞麦冻干物）经过丙酮提取；使用装有与苯基结合的树脂的固相萃取柱来洗脱发酵荞麦丙酮提取物，使用含甲酸的水作为洗脱剂；并使用装有与五氟苯基结合的载体的柱（PFP柱）来分馏和纯化洗脱物，使用含甲酸/甲醇的水作为流动相。这种功能性健康食品或药用组合物含有所述提取物或其至少一部分作为活性成分。