N,N'-(4,4'-sulfonyldiphenylene)-bis-(2-phenyl-isoindole-1,3-dione) | 85438-53-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: N,N'-(4,4'-sulfonyldiphenylene)-bis-(2-phenyl-isoindole-1,3-dione)
• 英文别名: 2,2'-(4,4'-sulfonylbis(4,1-phenylene))diisoindoline-1,3-dione；N,N'-4,4'-diphenylenesulfonebisphthalimide；bis-(4-phthalimido-phenyl)-sulfone；Bis-(4-phthalimido-phenyl)-sulfon；4,4'-bis(phthalimido)diphenyl sulfone；2,2'-[Sulfonyldi(4,1-phenylene)]di(1H-isoindole-1,3(2H)-dione)；2-[4-[4-(1,3-dioxoisoindol-2-yl)phenyl]sulfonylphenyl]isoindole-1,3-dione
• CAS: 85438-53-5
• 化学式: C₂₈H₁₆N₂O₆S
• 分子量: 508.511
• InChiKey: YPEVDIBALQEQNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  37
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  117
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  苯酐 、 氨苯砜 在 吡啶 作用下， 生成 N,N'-(4,4'-sulfonyldiphenylene)-bis-(2-phenyl-isoindole-1,3-dione)
  参考文献：
  名称：

  11. 4：4'-二氨基二苯砜的羧酸衍生物

  摘要：

  DOI：

  10.1039/jr9420000042

文献信息

• Synthesis and in vitro anti Mycobacterium tuberculosis activity of a series of phthalimide derivatives
  作者：Jean L. Santos、Paulo R. Yamasaki、Chung Man Chin、Célio H. Takashi、Fernando R. Pavan、Clarice Q.F. Leite

  DOI：10.1016/j.bmc.2009.04.042

  日期：2009.6

  New phthalimide derivatives were easily prepared through condensation of phthalic anhydride and selected amines with variable yields (70–90%). All compounds (3a–l) were evaluated against Mycobacterium tuberculosis H37Rv using Alamar Blue susceptibility. The compounds 3c, 3i, and 3l have the minimum inhibitory concentrations (MICs) of 3.9, 7.8, and 5.0 μg/mL, respectively, and could be considered new

  新的邻苯二甲酰亚胺衍生物很容易通过邻苯二甲酸酐和选定的胺的缩合反应以可变的收率（70-90％）来制备。使用Alamar Blue药敏性评估了所有化合物（3a – l）对结核分枝杆菌H 37 Rv的抵抗力。化合物3c，3i和3l的最低抑菌浓度（MIC）分别为3.9、7.8和5.0μg/ mL，可被视为治疗结核病和耐多药结核病的新的先导化合物。
• Process for producing a film-like and fibrous article of a wholly aromatic polyester
  申请人：TEIJIN LIMITED

  公开号：EP0070539A1

  公开（公告）日：1983-01-26

  A wholly aromatic polyester composition comprising (a) 100 parts by weight of a wholly aromatic polyester containing as a main component at least one compound selected from the group consisting of aromatic dicarboxylic acids, aromatic dihydroxy compounds and aromatic hydroxycarboxylic acids, and (b) from 5 to 300 parts by weight of a low-molecular-weight compound being substantially non-reactive with the wholly aromatic polyester and having a boiling point of at least about 200°C under atmospheric pressure and a molecular weight of not more than 1.000. The wholly aromatic polyester composition is produced advantageously by polycondensing in the molten state the polyester-forming starting mixture in the presence of the low-molecular-weight compound. A film-like or fibrous article of a wholly aromatic polyester may be produced by extracting the low-molecular-weight compound from a film-like or fibrous article of the wholly aromatic polyester composition.

  全芳香族聚酯组合物，包括 (a) 100 份（按重量计）全芳香族聚酯，其主要成分含有至少一种选自芳香族二 羧酸、芳香族二羟基化合物和芳香族羟基羧酸的化合物，以及 (b) 5 至 300 重量份的低分子量化合物，该化合物与全芳香族聚酯基本不发生 反应，在常压下沸点至少约为 200℃，分子量不超过 1.000。 全芳香族聚酯组合物的有利生产方法是在低分子量化合物存在下，在熔融状态下对聚酯形成起始混合物进行缩聚。 全芳香族聚酯的薄膜状或纤维状制品可通过从全芳香族聚酯组合物的薄膜状或纤维状制品中提取低分子量化合物而制成。
• Production of a film-like or fibrous structure of an aromatic polyester
  申请人：TEIJIN LIMITED

  公开号：EP0057387A2

  公开（公告）日：1982-08-11

  A process for producing a film-like or fibrous structure of an aromatic polyester, which comprises (1) forming an unstretched film-like or fibrous structure by melt-shaping a blend comprising 100 parts by weight of (A) an aromatic polyester having a high degree of polymerization derived from an aromatic dicarboxylic acid as a main acid component and an aliphatic diol and/or an alicyclic diol as a main glycol component and (B) 3 to 300 parts by weight of a low-molecular-weight compound being substantially non-reactive with the aromatic polyester (A) and having a boiling point of at least about 200°C under atmospheric pressure and a molecular weight of not more than 1,000, (2) stretching the resulting film-like or fibrous structure, (3) extracting at least a major portion of the low-molecular-weight compound from the stretched film-like or fibrous structure by using an organic solvent which does not substantially dissolve the aromatic polyester under the extracting conditions, and (4) if desired, heat-setting the film-like or fibrous structure after the stretching step (2) and/or the extracting step (3). The film-like or fibrous structure of an aromatic polyester prepared by the process substantially contains no low-molecular-weight compound or contains the low-molecular-weight compound in an amount of up to about 1 part by weight at most per 100 parts by weight of the aromatic polyester.

  一种生产芳香族聚酯膜状或纤维状结构的工艺，包括 (1) 通过熔融定型混合料形成一种未拉伸的膜状或纤维状结构，该混合料包括：(A) 以芳香族二羧酸为主要酸组分，以脂肪族二元醇和/或脂环族二元醇为主要二元醇组分的具有高聚合度的芳香族聚酯；(B) 3 至 300 份（重量）与芳香族聚酯(A)基本不反应且沸点至少约为 200℃的低分子量化合物；(C) 100 份（重量）与芳香族聚酯(A)具有高聚合度的芳香族聚酯。(B) 3 至 300 重量份的低分子量化合物，该化合物基本上不与芳香族聚酯 (A) 反应，在常压下的沸点至少约为 200°C，分子量不超过 1、000, (2) 拉伸得到的薄膜状或纤维状结构、 (3) 使用在萃取条件下基本上不溶解芳香族聚酯的有机溶剂，从拉伸的膜状或纤维状结构中萃取至少大部分低分子量化合物，以及 (4) 如果需要，在拉伸步骤 (2) 和/或萃取步骤 (3) 之后对薄膜状或纤维状结构进行热固。 通过该工艺制备的芳香族聚酯的膜状或纤维状结构基本上不含低分子量化合物，或含低分子量化合物的量最多为每 100 份芳香族聚酯中约 1 份（重量）。
• 4,4'-Bis(phthalimid)diphenyl sulfone compounds, processes for their production and flame retardant polymer compositions containing them
  申请人：Tosoh Corporation

  公开号：EP0319916A2

  公开（公告）日：1989-06-14

  A 4,4′-bis(phthalimido)diphenyl sulfone compound having the formula: wherein X is a halogen atom, k = 0 to 4, ℓ = 0 to 4, m = 0 to 4 and n = 0 to 4, provided k+ℓ+m+n>1.

  一种 4,4′-双(邻苯二甲酰亚胺基)二苯砜化合物，其式如下 其中 X 是卤素原子，k = 0 至 4，ℓ = 0 至 4，m = 0 至 4 和 n = 0 至 4，条件是 k+ℓ+m+n>1.
• Electron-acceptor properties of N, N?-arylenebisphthalimides
  作者：D. V. Pebalk、B. V. Kotov、A. N. Pravednikov

  DOI：10.1007/bf00957932

  日期：1983.2