1-ethyl-4-(dimethylamino)pyridinium | 151009-35-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-ethyl-4-(dimethylamino)pyridinium
• 英文别名: 4-dimethylamino-1-ethyl-pyridinium；4-dimethylamino-1-ethyl-pyridinium cation；1-ethyl-N,N-dimethylpyridin-1-ium-4-amine
• CAS: 151009-35-7
• 化学式: C₉H₁₅N₂
• 分子量: 151.231
• InChiKey: XVBOLEXVQPOXEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  氢碘酸 、 碘 、 1-ethyl-4-(dimethylamino)pyridinium 、 bismuth(III) oxide 以 乙腈 为溶剂， 反应 1.0h， 以67%的产率得到
  参考文献：
  名称：

  One-Dimensional Diiodine–Iodobismuthate(III) Hybrids Cat₃{[Bi₂I₉](I₂)₃}: Syntheses, Stability, and Optical Properties

  摘要：

  One-dimensional iodine-rich iodobismuthates(III), Cat₃{[Bi₂I₉](I₂)₃} [Cat = 1,4-MePy (1) and 1-EtBMAP (2)], feature the highest amount of "trapped" diiodine units in polyhalogen-halometalates of p-block elements. Both complexes have narrow optical band gaps (1.55 and 1.63 eV, respectively) and moderate thermal stability.

  DOI：

  10.1021/acs.inorgchem.0c02599

文献信息

• [EN] DIAGNOSING AND TREATING CANCER<br/>[FR] DIAGNOSTIC ET TRAITEMENT DU CANCER
  申请人：UNIV PENNSYLVANIA

  公开号：WO2014165216A1

  公开（公告）日：2014-10-09

  The invention relates to compositions and methods for diagnosing as well as treating cancer diseases associated with choline kinase (ChoK). Specifically, the invention relates to a composition comprising an intrinsically fluorescent choline kinase (ChoK) inhibitor or a ChoK inhibitor operably linked to a fluorescent dye. The composition is capable of diagnosing and/or treating cancer diseases associated with ChoK.

  本发明涉及与胆碱激酶（ChoK）相关的癌症疾病的诊断和治疗的组合物和方法。具体而言，本发明涉及一种组合物，包括本质上荧光的胆碱激酶（ChoK）抑制剂或与荧光染料操作性链接的ChoK抑制剂。该组合物能够诊断和/或治疗与ChoK相关的癌症疾病。
• Electric Double-Layer Capacitor
  申请人：Kikuchi Taketoshi

  公开号：US20090103241A1

  公开（公告）日：2009-04-23

  An activated carbon comprising a carbonized and activated compound represented by the formula (1): (wherein, R represents a hydrocarbon group having 1 to 12 carbon atoms, said hydrocarbon group may be optionally substituted with hydroxyl group, alkyl group, alkoxy group, aryl group, aryloxy group, sulfonyl group, halogen atoms, nitro group, thioalkyl group, cyano group, carboxyl group, amino group or amide group, R′ represents hydrogen atom or methyl group, and n represents an integer of 4, 6, or 8).

  一种活性炭，包括由式（1）所表示的碳化和活化化合物： 其中，R表示具有1至12个碳原子的碳氢基团，该碳氢基团可以选择地被羟基、烷基、烷氧基、芳基、芳氧基、磺酰基、卤素原子、硝基、硫代烷基、氰基、羧基、氨基或酰胺基取代；R′表示氢原子或甲基基团；n表示4、6或8的整数。
• DIAGNOSING AND TREATING CANCER
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US20160220703A1

  公开（公告）日：2016-08-04

  The invention relates to compositions and methods for diagnosing as well as treating cancer diseases associated with choline kinase (ChoK). Specifically, the invention relates to a composition comprising an intrinsically fluorescent choline kinase (ChoK) inhibitor or a ChoK inhibitor operably linked to a fluorescent dye. The composition is capable of diagnosing and/or treating cancer diseases associated with ChoK.

  本发明涉及与胆碱激酶（ChoK）相关的癌症疾病的诊断和治疗的组合物和方法。具体而言，本发明涉及一种组合物，其包括本质上荧光的胆碱激酶（ChoK）抑制剂或与荧光染料操作性地连接的ChoK抑制剂。该组合物能够诊断和/或治疗与ChoK相关的癌症疾病。
• ELECTRIC DOUBLE LAYER CAPACITOR
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1905740A1

  公开（公告）日：2008-04-02

  An activated carbon comprising a carbonized and activated compound represented by the formula (1): (wherein, R represents a hydrocarbon group having 1 to 12 carbon atoms, said hydrocarbon group may be optionally substituted with hydroxyl group, alkyl group, alkoxy group, aryl group, aryloxy group, sulfonyl group, halogen atoms, nitro group, thioalkyl group, cyano group, carboxyl group, amino group or amide group, R' represents hydrogen atom or methyl group, and n represents an integer of 4, 6, or 8).

  一种活性炭，包含由式（1）代表的碳化和活化化合物： (其中，R 代表具有 1 至 12 个碳原子的烃基，所述烃基可选择性地被羟基、烷基、烷氧基、芳基、芳氧基、磺酰基、卤素原子、硝基、硫代烷基、氰基、羧基、氨基或酰胺基取代，R'代表氢原子或甲基，n 代表 4、6 或 8 的整数）。
• ACTIVATED CARBON AND METHOD FOR PRODUCING THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2093191A1

  公开（公告）日：2009-08-26

  An activated carbon obtained by activating a carbide of a compound (1) with an alkali metal hydroxide, wherein the compound (1) is obtained, for example, by dehydration condensation of a resorcinol and an aldehyde using an acid catalyst.

  通过用碱金属氢氧化物活化化合物(1)的碳化物而获得的活性炭，其中化合物(1)例如是通过使用酸催化剂对间苯二酚和醛进行脱水缩合而获得的。