2-(methylamino)-2',2''-diaminotriethylamine | 81497-21-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(methylamino)-2',2''-diaminotriethylamine
• 英文别名: N'-(2-aminoethyl)-N'-[2-(methylamino)ethyl]ethane-1,2-diamine
• CAS: 81497-21-4
• 化学式: C₇H₂₀N₄
• 分子量: 160.263
• InChiKey: FYXXEWOGHVSOGS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  67.3
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(methylamino)-2',2''-diaminotriethylamine 、 alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 作用下， 反应 2.0h， 生成
  参考文献：
  名称：

  一种制备3,5,5-三甲基-3-环己烯-1-酮的方 法

  摘要：

  一种3,5,5‑三甲基‑3‑环己烯‑1‑酮的制备方法：以3,5,5‑三甲基‑2‑环己烯‑1‑酮(α‑IP)为原料，以前氮磷川碱为催化剂，采用反应精馏技术来进行异构反应，制备3,5,5‑三甲基‑3‑环己烯‑1‑酮(β‑IP)，产品β‑IP的纯度可达到99.5wt％‑99.8wt％，反应选择性可达到99.2％‑99.9％。该工艺具有催化剂用量少、选择性高、不发生碱析、高沸物少等优点，是一种高效的合成工艺。

  公开号：

  CN107216244B
• 作为产物：
  描述：

  聚合甲醛 、 三(2-氨基乙基)胺 在 甲醇 、 sodium tetrahydroborate 作用下， 以 甲苯 为溶剂， 反应 12.0h， 生成 2-(methylamino)-2',2''-diaminotriethylamine
  参考文献：
  名称：

  一种制备3,5,5-三甲基-3-环己烯-1-酮的方 法

  摘要：

  一种3,5,5‑三甲基‑3‑环己烯‑1‑酮的制备方法：以3,5,5‑三甲基‑2‑环己烯‑1‑酮(α‑IP)为原料，以前氮磷川碱为催化剂，采用反应精馏技术来进行异构反应，制备3,5,5‑三甲基‑3‑环己烯‑1‑酮(β‑IP)，产品β‑IP的纯度可达到99.5wt％‑99.8wt％，反应选择性可达到99.2％‑99.9％。该工艺具有催化剂用量少、选择性高、不发生碱析、高沸物少等优点，是一种高效的合成工艺。

  公开号：

  CN107216244B

文献信息

• [EN] MOLECULAR DESIGN OF NEW ANTIBIOTICS AND ANTIBIOTIC ADJUVANTS AGAINST MCR STRAINS<br/>[FR] CONCEPTION MOLÉCULAIRE DE NOUVEAUX ANTIBIOTIQUES ET ADJUVANTS D'ANTIBIOTIQUES CONTRE LES SOUCHES MCR
  申请人：SINGAPORE HEALTH SERV PTE LTD

  公开号：WO2020236084A1

  公开（公告）日：2020-11-26

  The present invention relates to a compound comprising a hydrophobic moiety, a linker and N-containing moiety. The present invention also relates to the method of synthesizing the compound and the use of the compound as an antibiotic or an adjuvant for an antibiotic.

  本发明涉及一种包含疏水基团、连接剂和含氮基团的化合物。本发明还涉及合成该化合物的方法以及将该化合物用作抗生素或抗生素辅助剂的用途。
• METAL NANOPARTICLE-BASED CATALYTIC COMPOSITION THAT CONTAINS A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID, PROCESS FOR PREPARATION, PROCESS FOR HYDROGENATION OF AN OLEFINIC FEEDSTOCK
  申请人：Leger Bastien-Thésards

  公开号：US20100191027A1

  公开（公告）日：2010-07-29

  The object of this invention is a suspension of metal nanoparticles with a mean size of between 1 and 20 nanometers, in at least one non-aqueous ionic liquid, whereby said suspension also contains at least one nitrogen-containing ligand, in which said metal nanoparticles comprise at least one transition metal in the zero valence state that is selected from among rhodium, ruthenium, iridium, nickel, and platinum by themselves or in a mixture and in which said nitrogen-containing ligand is selected from the group that is formed by the linear compounds that comprise at least one nitrogen atom, whereby the non-aromatic cyclic compounds comprise at least one nitrogen atom, the non-condensed aromatic compounds comprise at least one nitrogen atom, the condensed aromatic compounds comprise at least one group of two aromatic cycles that are condensed two by two, and at least one nitrogen atom, whereby the condensed aromatic compounds comprise at least 3 aromatic cycles and 1 nitrogen atom, and whereby the condensed aromatic compounds comprise at least 3 aromatic cycles and at least 2 nitrogen atoms that are located in the same aromatic cycle.

  本发明的目的是提供一种金属纳米颗粒的悬浮液，其平均尺寸在1到20纳米之间，在至少一种非水离子液体中，该悬浮液还包含至少一种含氮配体，其中所述金属纳米颗粒至少包括一种零价态的过渡金属，所述过渡金属选自铑、钌、铱、镍和铂，可以单独使用或混合使用，并且所述含氮配体选自由至少一种氮原子组成的线性化合物组成的组，其中非芳香环化合物包括至少一个氮原子，非缩合芳香化合物包括至少一个氮原子，缩合芳香化合物包括至少两个芳香环两两缩合的一个氮原子组，至少三个芳香环和一个氮原子，缩合芳香化合物包括至少三个芳香环和至少两个位于同一芳香环中的氮原子。
• PROCESS FOR HYDROGENATION OF AN AROMATIC FEEDSTOCK THAT AS CATALYST USES A SUSPENSION OF METAL NANOPARTICLES CONTAINING A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID
  申请人：Leger Bastien Thesards

  公开号：US20100228064A1

  公开（公告）日：2010-09-09

  This invention describes a process for hydrogenation of an aromatic feedstock that as a catalytic composition uses a suspension of metal nanoparticles of a mean size of between 1 and 20 nanometers in at least one non-aqueous ionic liquid, whereby said suspension also contains at least one nitrogen-containing ligand, in which said metal nanoparticles comprise a transition metal in the zero-valence state, whereby the transition metal is selected from the groups 8, 9, 10 and 11 of the periodic table and in which said nitrogen-containing ligand comprises 1 to n nitrogen atoms, whereby n is an integer of between 1 and 20.

  这项发明描述了一种对芳香原料进行氢化的过程，其催化组合物使用至少一种非水离子液体中平均尺寸在1至20纳米之间的金属纳米颗粒的悬浮液，该悬浮液还包含至少一种含氮配体，其中所述金属纳米颗粒包括零价态的过渡金属，所述过渡金属选自周期表的8、9、10和11族，并且所述含氮配体包括1到n个氮原子，其中n是介于1和20之间的整数。
• BORAZINE-BASED RESIN, PROCESS FOR ITS PRODUCTION, BORAZINE-BASED RESIN COMPOSITION, INSULATING FILM AND METHOD FOR ITS FORMATION
  申请人：MATSUTANI Hiroshi

  公开号：US20110313122A1

  公开（公告）日：2011-12-22

  Interlayer insulating films 5,7 (insulating films) provided in a memory capacitor cell 8 are formed between a gate electrode 3 and a counter electrode 8 C formed on a silicon wafer 1. The interlayer insulating films 5,7 comprise a borazine-based resin, having a specific dielectric constant of no greater than 2.6, a Young's modulus of 5 GPa or greater and a leak current of no greater than 1×10 −8 A/cm 2 .

  存储器电容单元中提供的绝缘膜（绝缘膜）是在硅片1上形成的栅极3和对电极8C之间形成的。绝缘膜5,7包括一种基于硼氮烷的树脂，其介电常数不大于2.6，杨氏模量为5 GPa或更大，泄漏电流不大于1×10^-8A/cm2。
• AMIDE DERIVATIVES OF SQUALAMINE FOR THE TREATMENT OF INFECTIONS
  申请人：VIRBAC

  公开号：US20190262362A1

  公开（公告）日：2019-08-29

  A compound of formula (I) in which R′ represents a group —(CR a R b ) n —X—(CR c R d ) m —[Y—(CR e R f ) o ] t —NR 9 R 10 and X and Y independently represent a group —NR11-, a group —O— or a divalent 5-membered or 6-membered heterocyclic group comprising at least one nitrogen atom, and also the stereoisomers, mixtures of stereoisomers, and/or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical or veterinary compositions containing the compound of formula (I) and also to the use thereof as medicament, more particularly in the treatment of bacterial, fungal, viral or parasitic infections. Also further disclosed are pharmaceutical or veterinary compositions including the compound of formula (I) in combination with an antibiotic other than such a compound of formula (I).

  化合物的公式(I)，其中R′代表一个基团- (CRaRb)n-X-(CRcRd)m-[Y-(CReRf)o]t-NR9R10，X和Y分别代表一个基团-NR11-，一个基团-O-或者至少包含一个氮原子的二价五元或六元杂环基团，以及其立体异构体、立体异构体混合物和/或药学上可接受的盐。还公开了包含公式(I)化合物的制药或兽医组合物，以及在治疗细菌、真菌、病毒或寄生虫感染方面作为药物的用途。还公开了包含公式(I)化合物和除公式(I)化合物以外的抗生素的制药或兽医组合物。