2,3-Diphenyl-glutarsaeure-1-nitril | 97433-44-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2,3-Diphenyl-glutarsaeure-1-nitril
• 英文别名: 5-Cyan-3,5-diphenyl-buttersaeure；optically inactive 3,4-diphenyl-4-cyano-butyric acid；Opt.-inakt. 3,4-Diphenyl-4-cyan-buttersaeure；4-Cyan-3,4-diphenyl-buttersaeure；erythro-threo-4-Cyano-3,4-diphenylbutyric acid；4-Cyano-3,4-diphenylbutyric acid；4-cyano-3,4-diphenylbutanoic acid
• CAS: 97433-44-8
• 化学式: C₁₇H₁₅NO₂
• 分子量: 265.312
• InChiKey: FZNDGCLOBXTABS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  61.1
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,3-Diphenyl-glutarsaeure-1-nitril 在 potassium permanganate 作用下， 生成 3,4-diphenyl-4-oxobutanoic acid
  参考文献：
  名称：

  Avery; Mc Dole, Journal of the American Chemical Society, 1908, vol. 30, p. 1424

  摘要：

  DOI：
• 作为产物：
  描述：

  cyano-4 diphenyl-3,4 butanoate d'ethyle 在 氢氧化钾 作用下， 以 乙醇 、 水 为溶剂， 以38.1 g (84.2%)的产率得到2,3-Diphenyl-glutarsaeure-1-nitril
  参考文献：
  名称：

  Polysubstituted butanoic acids, esters and derivatives thereof utilizing

  摘要：

  提供了多取代丁酸、酯及其衍生物，以及制备这些化合物的方法和利用这些多取代丁酸、酯及其衍生物的除草剂组合物。

  公开号：

  US04224052A1

文献信息

• 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS
  申请人：Mosrin Marc

  公开号：US20140235446A1

  公开（公告）日：2014-08-21

  The compounds of the formula (I) in which L represents a radical of the formula and A 1 , B 1 and A 2 and B 2 are as defined in Claim 1, are suitable as herbicides for the control of harmful plants or as plant growth regulators. The compounds can be prepared by the process of Claim 12.

  式(I)中L代表式的基团，A1、B1、A2和B2如权利要求1所定义，适用于作为除草剂用于控制有害植物或作为植物生长调节剂。这些化合物可以通过权利要求12所述的方法制备。
• SUBSTITUTED (3R,4R)-4-CYAN-3,4-DIPHENYLBUTANOATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS
  申请人：Jakobi Harald

  公开号：US20140194291A1

  公开（公告）日：2014-07-10

  Substituted (3R,4R)-4-cyano-3,4-diphenylbutanoates, processes for their preparation and their use as herbicides and plant growth regulators Compounds of the formula (I) or salts thereof and salts thereof, in each case in the optically active (3R,4R)-threo form, R 1 is hydrogen or a hydrolyzable radical, and (R 2 ) n , (R 3 ) m , n and m are as defined in formula (I) according to claim 1, where the stereochemical configuration at the carbon atom in position 3 of the butanoic acid derivative has a stereochemical purity of 60 to 100% (R), preferably 70 to 100% (R), more preferably 80 to 100% (R), in particular 90 to 100% (R), based on the mixture of threo enantiomers present, and the stereochemical configuration at the carbon atom in position 4 of the butanoic acid derivative has a stereochemical purity of 60 to 100% (R), preferably 70 to 100% (R), more preferably 80 to 100% (R), in particular 90 to 100% (R), based on the mixture of threo enantiomers present, are suitable for use as herbicides and growth regulators, in particular for the selective use in plant crops, and can be prepared by the process of claim 9.

  (3R,4R)-4-氰基-3,4-二苯基丁酸酯的替代物，其制备方法以及其作为除草剂和植物生长调节剂的用途化合物的公式（I）或其盐及其盐，每种情况下均为光学活性的（3R,4R）-threo形式，R1为氢或可水解基，而（R2）n，（R3）m，n和m如公式（I）根据权利要求1所定义，其中在丁酸衍生物中第3位碳原子的立体化学配置具有60至100%（R）的立体化学纯度，优选70至100%（R），更优选80至100%（R），特别是90至100%（R），基于目前存在的threo对映体混合物，而在丁酸衍生物中第4位碳原子的立体化学配置具有60至100%（R）的立体化学纯度，优选70至100%（R），更优选80至100%（R），特别是90至100%（R），基于目前存在的threo对映体混合物，适用于作为除草剂和生长调节剂使用，特别是用于植物作物的选择性使用，并且可以通过权利要求9的方法制备。
• SUBSTITUTED 4-CYANO-3-PHENYL-4-(PYRIDIN-3-YL)BUTANOATES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS
  申请人：BAYER INTELLECTUAL PROPERTY GMBH

  公开号：US20140296073A1

  公开（公告）日：2014-10-02

  Compounds of the formula (I) or salts thereof, in which (R 1 ) m , (R 2 ) n , R 3 and R 4 as defined in Claim 1 are suitable as herbicides for the control of harmful plants or as plant growth regulators. The compounds can be prepared by the processes of Claim 7.

  化合物的分子式（I）或其盐，其中（R1）m，（R2）n，R3和R4如权利要求1中定义的，适用于作为除草剂控制有害植物或作为植物生长调节剂。这些化合物可以通过权利要求7中的方法制备。
• SUBSTITUTED 4-CYAN-3-(2,6-DIFLUOROPHENYL)-4-PHENYLBUTANOATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS
  申请人：Jakobi Harald

  公开号：US20140087945A1

  公开（公告）日：2014-03-27

  Compounds of the formula (I) or salts thereof, in which R 1 is H or a hydrolyzable radical, (R 2 ) n is n substituents R 2 , where R 2 independently of the others is Hal, CN, NO 2 , (C 1 -C 8 )-alkyl, (C 1 -C 8 )-alkoxy, (C 1 -C 8 )-alkylthio, (C 1 -C 8 )-alkylsulfinyl, (C 1 -C 8 )-alkylsulfonyl, (C 1 -C 6 )-haloalkyl, (C 1 -C 6 )-haloalkoxy, (C 1 -C 6 )-haloalkylthio, (C 1 -C 6 )-haloalkylsulfinyl, (C 1 -C 6 )-haloalkylsulfonyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, tri-[(C 1 -C 4 )-alkyl]-silyl or tri-[(C 1 -C 4 )-alkyl]-silyl-(C 1 -C 4 )-alkyl or where in each case two groups R 2 located ortho at the ring together are —Z 1 -A*-Z 2 , in which A* is (C 1 -C 4 )-alkylene, which is optionally substituted by radicals from the group consisting of halogen, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-haloalkyl, (C 1 -C 4 )-alkoxy and (C 1 -C 4 )-haloalkoxy, Z 1 , Z 2 are each a direct bond, O or S and where the group —Z 1 -A*-Z 2 together with the carbon atoms, attached to the group, of the phenyl ring form a fused-on 5- or 6-membered ring, and n is 0, 1, 2, 3, 4 or 5, excluding the compound in which R 1 is methyl and (R 2 ) n is 3-fluoro (n=1), are suitable for use as herbicides and plant growth regulators and can be prepared by the process of claim 8.

  化合物的化学式（I）或其盐，其中R1为H或可水解的基团，（R2）n为n个取代基R2，其中R2独立于其他基团，为Hal、CN、NO2、（C1-C8）-烷基、（C1-C8）-烷氧基、（C1-C8）-烷基硫基、（C1-C8）-烷基亚砜基、（C1-C8）-烷基砜基、（C1-C6）-卤代烷基、（C1-C6）-卤代烷氧基、（C1-C6）-卤代烷基硫基、（C1-C6）-卤代烷基亚砜基、（C1-C6）-卤代烷基砜基、（C2-C6）-烯基、（C2-C6）-炔基、三-[(C1-C4）-烷基]-硅基或三-[(C1-C4）-烷基]-硅基（C1-C4）-烷基，或其中每种情况下两个位于环上的R2基团一起为—Z1-A*-Z2，其中A*为（C1-C4）-烷基，可选择地被来自卤素、（C1-C4）-烷基、（C1-C4）-卤代烷基、（C1-C4）-烷氧基和（C1-C4）-卤代烷氧基的基团取代，Z1、Z2分别为直接键、O或S，并且—Z1-A*-Z2基团与连接到苯环的碳原子一起形成一个螺联的5-或6-成员环，n为0、1、2、3、4或5，不包括R1为甲基且（R2）n为3-氟（n=1）的化合物，适用于用作除草剂和植物生长调节剂，并可通过第8项权利要求的方法制备。
• SUBSTITUTED 5-HYDROXY-2-PHENYL-3-HETEROARYL PENTANENITRILE DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND/OR PLANT GROWH REGULATORS
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：US20170290330A1

  公开（公告）日：2017-10-12

  Primarily, the present invention relates to compounds of the formula (I) defined below and to their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention also relates to herbicidal or plant growth-regulating compositions comprising one or more compounds of the formula (I). Moreover, the present invention relates to processes for preparing the compounds of the formula (I).

  主要地，本发明涉及以下定义的式(I)化合物以及它们作为除草剂的用途，特别是用于控制有用植物作物中的阔叶杂草和/或杂草，或作为植物生长调节剂以影响有用植物作物的生长。本发明还涉及包含一个或多个式(I)化合物的除草剂或植物生长调节剂组合物。此外，本发明涉及制备式(I)化合物的方法。