9-Methyl-9H-purine-8-carboxylic acid | 1234298-94-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: 9-Methyl-9H-purine-8-carboxylic acid
• 英文别名: 9-methylpurine-8-carboxylic acid
• CAS: 1234298-94-2
• 化学式: C₇H₆N₄O₂
• 分子量: 178.15
• InChiKey: VHJIIZISDQLNKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  80.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• CARBOXYLATION CATALYSTS
  申请人：Nolan Steven P.

  公开号：US20130085276A1

  公开（公告）日：2013-04-04

  The use of a complex of the form Z—M—OR in the carboxylation of a substrate is described. The group Z is a two-electron donor ligand, M is a metal and OR is selected from the group consisting of OH, alkoxy and aryloxy. The substrate may be carboxylated at a C—H or N—H bond. The metal M may be copper, silver or gold. The two-electron donor ligand may be a phosphine, a carbene or a phosphite ligand. Also described are methods of manufacture of the complexes and methods for preparing isotopically labelled caboxylic acids and carboxylic acid derivatives.

  描述了在底物羧化反应中使用形式为Z—M—OR的复合物。其中，Z是一个双电子供体配体，M是金属，OR从包括OH、烷氧基和芳基氧基的基团中选择。底物可以在C—H或N—H键上进行羧化。金属M可以是铜、银或金。双电子供体配体可以是膦、卡宾或膦酸酯配体。还描述了复合物的制备方法以及制备同位素标记的羧酸和羧酸衍生物的方法。
• US9120711B2
  申请人：——

  公开号：US9120711B2

  公开（公告）日：2015-09-01
• [EN] CARBOXYLATION CATALYSTS<br/>[FR] CATALYSEURS DE CARBOXYLATION
  申请人：UNIV ST ANDREWS

  公开号：WO2011154700A1

  公开（公告）日：2011-12-15

  The use of a complex of the form Z-M-OR in the carboxylation of a substrate is described. The group Z is a two-electron donor ligand, M is a metal and OR is selected from the group consisting of OH, alkoxy and aryloxy. The substrate may be carboxylated at a C-H or N-H bond. The metal M may be copper, silver or gold. The two-electron donor ligand may be a phosphine, a carbene or a phosphite ligand. Also described are methods of manufacture of the complexes and methods for preparing isotopically labelled caboxylic acids and carboxylic acid derivatives.