3-chloronaphthalene-1,2-diol | 61978-18-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-chloronaphthalene-1,2-diol
• 英文别名: 3-chloro-naphthalene-1,2-diol；3-Chlor-1.2-dioxy-naphthalin；3-Chlor-naphthalin-1,2-diol
• CAS: 61978-18-5
• 化学式: C₁₀H₇ClO₂
• 分子量: 194.617
• InChiKey: XLYUUPZRQATRQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-萘醌 在 二氧化硫 、 氯 、 溶剂黄146 作用下， 生成 3-chloronaphthalene-1,2-diol
  参考文献：
  名称：

  Zincke, Chemische Berichte, 1886, vol. 19, p. 2499

  摘要：

  DOI：

文献信息

• (Meth)acryloyl compound and method for producing same
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US10723690B2

  公开（公告）日：2020-07-28

  A (meth)acryloyl compound represented by the following formula (A): wherein X is a 2m-valent group having 1 to 60 carbon atoms or a single bond; each Z is independently an oxygen atom, a sulfur atom, or not a crosslink; each R1 is independently a linear, branched, or cyclic alkyl group having 1 to 30 carbon atoms, an aryl group having 6 to 30 carbon atoms and optionally having a substituent, an alkenyl group having 2 to 30 carbon atoms and optionally having a substituent, an alkoxy group having 1 to 30 carbon atoms and optionally having a substituent, a halogen atom, a nitro group, an amino group, a carboxylic acid group, a thiol group, a hydroxy group, or a group in which a hydrogen atom of a hydroxy group is replaced with a vinylphenylmethyl group, wherein the alkyl group, the aryl group, the alkenyl group, or the alkoxy group optionally contains an ether bond, a ketone bond, or an ester bond; each R1A is independently a methyl group or a hydrogen atom; each k is independently an integer of 0 to 2, provided that all of the k moieties are not 0 at the same time; m is an integer of 1 to 3; each n is independently an integer of 0 to 5; and each p is independently 0 or 1.

  一种由以下公式（A）表示的（甲）基丙烯酰化合物：其中X是具有1至60个碳原子或单键的2m价基团；每个Z独立地是氧原子、硫原子或非交联；每个R1独立地是具有1至30个碳原子的线性、支链或环烷基基团，具有6至30个碳原子并且可选地具有取代基的芳基，具有2至30个碳原子并且可选地具有取代基的烯基基团，具有1至30个碳原子并且可选地具有取代基的烷氧基团，卤素原子，硝基基团，氨基，羧基，硫醇基，羟基，或氢氧基的氢原子被乙烯基苄基团取代的基团，其中烷基基团，芳基，烯基基团或烷氧基团可选地含有醚键，酮键或酯键；每个R1A独立地是甲基基团或氢原子；每个k独立地是0至2的整数，前提是所有k基团不同时为0；m是1至3的整数；每个n独立地是0至5的整数；每个p独立地是0或1。
• NOVEL ARYL COMPOUND AND METHOD FOR PRODUCING SAME
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP2955169A1

  公开（公告）日：2015-12-16

  The allyl compound of the present invention is represented by general formula (α): wherein ring Z1 is a naphthalene ring, ring Z2 is a benzene ring or a naphthalene ring, X is a hydrogen atom or a monovalent substituent having 1 to 18 carbon atoms, R is each independently an alkyl group having 1 to 4 carbon atoms or a halogen atom, m is 1 or 2, n is each independently an integer of 0 to 5, and when m is 1, the ring Z1 and the ring Z2 are bonded to each other via an oxygen atom.

  本发明的烯丙基化合物由通式 (α)表示： 其中，环 Z1 是萘环；环 Z2 是苯环或萘环；X 是氢原子或具有 1 至 18 个碳原子的一价取代基；R 独立地分别是具有 1 至 4 个碳原子的烷基或卤素原子；m 是 1 或 2；n 独立地分别是 0 至 5 的整数；当 m 为 1 时，环 Z1 和环 Z2 通过氧原子相互键合。
• NEW (METH)ACRYLOYL COMPOUND AND PRODUCTION METHOD FOR SAME
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP3326997A1

  公开（公告）日：2018-05-30

  A (meth)acryloyl compound represented by the following formula (A): wherein X is a 2m-valent group having 1 to 60 carbon atoms or a single bond; each Z is independently an oxygen atom, a sulfur atom, or not a crosslink; each R1 is independently a linear, branched, or cyclic alkyl group having 1 to 30 carbon atoms, an aryl group having 6 to 30 carbon atoms and optionally having a substituent, an alkenyl group having 2 to 30 carbon atoms and optionally having a substituent, an alkoxy group having 1 to 30 carbon atoms and optionally having a substituent, a halogen atom, a nitro group, an amino group, a carboxylic acid group, a thiol group, a hydroxy group, or a group in which a hydrogen atom of a hydroxy group is replaced with a vinylphenylmethyl group, wherein the alkyl group, the aryl group, the alkenyl group, or the alkoxy group optionally contains an ether bond, a ketone bond, or an ester bond; each R1A is independently a methyl group or a hydrogen atom; each k is independently an integer of 0 to 2, provided that all of the k moieties are not 0 at the same time; m is an integer of 1 to 3; each n is independently an integer of 0 to 5; and each p is independently 0 or 1.

  下式(A)代表的(甲基)丙烯酰化合物： 其中 X 是具有 1 至 60 个碳原子的 2m 价基团或单键；每个 Z 独立地是氧原子、硫原子或不是交联剂；每个 R1 独立地是具有 1 至 30 个碳原子的直链、支链或环状烷基、具有 6 至 30 个碳原子并可选择具有取代基的芳基、具有 2 至 30 个碳原子并可选择具有取代基的烯基、具有 1 至 30 个碳原子并可选择具有取代基的烷氧基、卤素原子、硝基、氨基、羧酸基、硫醇基、羟基或羟基的氢原子被乙烯基苯甲基取代的基团，其中烷基、芳基、烯基或烷氧基可选择含有醚键、酮键或酯键；每个 R1A 独立地为甲基或氢原子；每个 k 独立地为 0 至 2 的整数，条件是所有 k 分子不同时为 0；m 为 1 至 3 的整数；每个 n 独立地为 0 至 5 的整数；每个 p 独立地为 0 或 1。
• Zincke; Schmidt, Chemische Berichte, 1894, vol. 27, p. 2758
  作者：Zincke、Schmidt

  DOI：——

  日期：——
• Selective 1,4-Addition of Arenes to 3-Chloro-3-cyclobutene-1,2-dione under Friedel−Crafts Conditions. Synthesis and Reactivity of 4-Aryl-3-chloro-2-hydroxy-2-cyclobuten-1-ones¹
  作者：Arthur H. Schmidt、Gunnar Kircher、Stephan Maus、Heinz Bach

  DOI：10.1021/jo952062r

  日期：1996.1.1

  The reaction of semisquaric chloride (7) with arenes 2 has been investigated. In the presence of 1.1 equiv of AlCl3 and in the temperature range of -15 degrees C to rt the arenes 2a-q afford the 4-aryl-3-chloro-2-hydroxy-2-cyclobuten-1-ones (chloroenols) 8a-q in good yield. By contrast, 7 reacts with 1,4-dimethoxybenzene (21) in boiling CH2Cl2 to give a mixture of (2,5-dimethoxyphenyl)cyclobutenedione (9a) (27% yield) and bis(2,5-dimethoxyphenyl)cyclobutenedione (10a) (8% yield). With 1,2,4-trimethoxybenzene (2r) in the presence of trifluoroacetic acid is generated (2,4,5-trimethoxyphenyl)cyclobutenedione (9b) in 21% yield. The chloroenols 8 allow a series of valuable transformation reactions: with diazomethane the chloroenol methyl ethers 11 are generated, with chlorine the 3-aryl-4-chlorocyclobutenediones 12, and with bromine in MeOH the 3-aryl-4-methoxycyclobutenediones 13. In DMSO or in acetone/H2O the chloroenols 8 eliminate HCl, furnishing the arylcyclobutenediones 14. In a mixture of acetone -d(6)/D2O/DCl are obtained 4-aryl-cyclobutenediones-3-d 15. For the latter two processes the corresponding 3-aryl-4-chlorocyclobutane-1,2-diones 16 are postulated as intermediates. Thermolysis of the chloroenols 8 and the chloroenol methyl ethers 11 in refluxing m-xylene afforded the 3-chloro-1,2-dihydroxynaphthalenes 17 and the 3-chlorol-hydroxy-2-methoxynaphthalenes 18, respectively.