2-tridecanyl-1,4-naphthoquinone | 134650-32-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-tridecanyl-1,4-naphthoquinone
• 英文别名: 2-Tridecyl-1,4-naphthoquinone；2-tridecylnaphthalene-1,4-dione
• CAS: 134650-32-1
• 化学式: C₂₃H₃₂O₂
• 分子量: 340.506
• InChiKey: ICRHCIWNLXIPQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  25
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-tridecanyl-1,4-naphthoquinone 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 0.5h， 以92%的产率得到2-tridecanyl-1,4-naphthodiol
  参考文献：
  名称：

  Solid-phase organic synthesis of 2-tridecanyl-1,4-naphthoquinone and 2-tridecanyl-1,4-naphthodiol that form redox-active micelles and vesicles

  摘要：

  The solid-phase synthesis of new amphiphilic compounds is reported. It is based on a newly designed 1,4-naphthoquinone derivative that contains polar and nonpolar groups and self-assembles into micelles or vesicles in water depending on the concentration. They also display redox-active properties. (C) 2014 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.bioorg.2014.06.005
• 作为产物：
  描述：

  2-tridecanyl-1,4-naphthodiol 在 氧气 作用下， 反应 1.0h， 以99%的产率得到2-tridecanyl-1,4-naphthoquinone
  参考文献：
  名称：

  Solid-phase organic synthesis of 2-tridecanyl-1,4-naphthoquinone and 2-tridecanyl-1,4-naphthodiol that form redox-active micelles and vesicles

  摘要：

  The solid-phase synthesis of new amphiphilic compounds is reported. It is based on a newly designed 1,4-naphthoquinone derivative that contains polar and nonpolar groups and self-assembles into micelles or vesicles in water depending on the concentration. They also display redox-active properties. (C) 2014 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.bioorg.2014.06.005

文献信息

• Liu, Benli; Gu, Lianquan; Zhang, Jingling, Recueil des Travaux Chimiques des Pays-Bas, 1991, vol. 110, # 4, p. 99 - 103
  作者：Liu, Benli、Gu, Lianquan、Zhang, Jingling

  DOI：——

  日期：——
• LIU, BENLI;GU, LIANQUAN, XUACHZHUN SHIFAN DASYUEH SYUEHBAO, 24,(1990) N, S. 43-46
  作者：LIU, BENLI、GU, LIANQUAN

  DOI：——

  日期：——
• METHODS OF SCREENING AGENTS FOR CYTOTOXIC AND ANTIMICROBIAL ACTIVITY
  申请人：Aguilera J. Renato

  公开号：US20080020421A1

  公开（公告）日：2008-01-24

  The present invention provides for methods of screening agents for cytotoxic and/or anti-microbial activity. In particular embodiments, the loss of a fluorescent signal from the treated cells, due to cell death or inhibition of growth, is measured for several different cell types in parallel.
• Solid-phase organic synthesis of 2-tridecanyl-1,4-naphthoquinone and 2-tridecanyl-1,4-naphthodiol that form redox-active micelles and vesicles
  作者：Alejandro Bugarin、Luis E. Martinez、Peter Cooke、Tadiqul Islam、Juan C. Noveron

  DOI：10.1016/j.bioorg.2014.06.005

  日期：2014.10

  The solid-phase synthesis of new amphiphilic compounds is reported. It is based on a newly designed 1,4-naphthoquinone derivative that contains polar and nonpolar groups and self-assembles into micelles or vesicles in water depending on the concentration. They also display redox-active properties. (C) 2014 Elsevier Inc. All rights reserved.