naphth<1,2-d>-1,3-oxathiol-2-one | 22791-05-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: naphth<1,2-d>-1,3-oxathiol-2-one
• 英文别名: naphtho[1,2-d][1,3]oxathiol-2-one；Naphtho<1,2-d>thioxol-2-on；Naphth[1,2-d][1,3]oxathiol-2-on；Benzo[e][1,3]benzoxathiol-2-one
• CAS: 22791-05-5
• 化学式: C₁₁H₆O₂S
• 分子量: 202.233
• InChiKey: LDDQHGDZWDSPMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  naphth<1,2-d>-1,3-oxathiol-2-one 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 以70%的产率得到1-sulfanyl-2-naphthalenol
  参考文献：
  名称：

  Regiocontrolled Carbonylsulfanylations at ortho-Position of Phenols and at α-Position of Ketones Using Chlorocarbonylsulfenyl Chloride

  摘要：

  DOI：

  10.3987/com-98-s(h)23
• 作为产物：
  描述：

  S-(2-hydroxy-1-naphthyl)isothiouronium bromide 在 盐酸 作用下， 以 溶剂黄146 为溶剂， 反应 5.0h， 以25%的产率得到naphth<1,2-d>-1,3-oxathiol-2-one
  参考文献：
  名称：

  Sharma; Saxena; Gupta, Journal of the Indian Chemical Society, 1990, vol. 67, # 10, p. 812 - 814

  摘要：

  DOI：

文献信息

• Neuroprotective benzo 1 3 oxathiol 2 ones
  申请人：Jaquith B. James

  公开号：US20060234987A1

  公开（公告）日：2006-10-19

  This invention relates to benzo[1,3]oxathiol-2-ones, derivatives, and precursors thereof, and their use as neuroprotective agents in the treatment and prevention of neuronal disorders of the central and peripheral nervous systems.

  本发明涉及苯并[1,3]噁硫-2-酮、其衍生物和前体物，以及它们作为神经保护剂在治疗和预防中枢和外周神经系统的神经元疾病中的应用。
• Career management practices: An empirical survey and implications
  作者：Yehuda Baruch、Maury Peiperl

  DOI：10.1002/1099-050x(200024)39:4<347::aid-hrm6>3.0.co;2-c

  日期：——

  A key ingredient in the knowledge economy is the development of people's careers. Companies approach career development in a variety of ways. To better understand how these approaches fit together and how they are used to address different situations, the authors surveyed 194 United Kingdom companies and identified five groups of practices. These groups were associated with certain organizational characteristics. Drawing on concepts from the careers literature, the authors suggest a two-dimensional model to explore how these groups of practices can be systematically understood and applied. (C) 2000 John Wiley & Sons, Inc.
• Tsukamoto et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1953, vol. 73, p. 1083
  作者：Tsukamoto et al.

  DOI：——

  日期：——
• Palladium-Catalyzed Intramolecular Oxidative CH Sulfuration of Aryl Thiocarbamates
  作者：Yingwei Zhao、Yinjun Xie、Chungu Xia、Hanmin Huang

  DOI：10.1002/adsc.201400306

  日期：2014.8.11

  AbstractA palladium‐catalyzed intramolecular CH bond sulfuration reaction of aryl thiocarbamates has been developed. This strategy provides a new route to benzo[d][1,3]oxathiol‐2‐ones with tolerance of a wide range of substituents. Mechanistic studies suggested that the CH activation–sulfuration to afford 2‐imino‐1,3‐benzoxathiole intermediate might involve an electrophilic palladation process.magnified image
• QUALITY ASSURANCE PROCEDURES FOR THE MODAL TESTING OF BUILDING FLOOR STRUCTURES
  作者：P. Reynolds、A. Pavic

  DOI：10.1111/j.1747-1567.2000.tb00924.x

  日期：2000.7