3-epi-2-deoxyecdysone | 77732-73-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3-epi-2-deoxyecdysone
• 英文别名: (3R,5R,9R,10R,13R,14S,17R)-17-[(2S,3R)-3,6-dihydroxy-6-methylheptan-2-yl]-3,14-dihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
• CAS: 77732-73-1
• 化学式: C₂₇H₄₄O₅
• 分子量: 448.643
• InChiKey: CRAPXAGGASWTPU-DUIYOXMUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-epi-2-deoxyecdysone 、 β-环糊精 以 乙醇 、 水 为溶剂， 反应 8.0h， 生成
  参考文献：
  名称：

  Supramolecular Complexes of 3-Epi-2-deoxyecdysone with Cyclodextrins and Their Anti-Inflammatory Activity

  摘要：

  The ecdysteroid 3-epi-2-deoxyecdysone has been isolated from the aerial part of Acanthophyllum gypsophiloides Regel. The complexes formation of the ecdysteroid with -, -, -, and 2-hydroxypropyl--cyclodextrins has been studied by means of NMR spectroscopy. Anti-inflammatory activity of the obtained 3-epi-2-deoxyecdysone complexes with cyclodextrins has been investigated.

  DOI：

  10.1134/s1070363219030095

文献信息

• Natural product derivatives as food supplements and pharmaceuticals
  申请人：Amato K. Daniel

  公开号：US20050191385A1

  公开（公告）日：2005-09-01

  Then present invention provides new and useful derivatives of phyto-derived tetracyclic compounds possessing steroidal-like activity, and in some instances both amino acid/oligo-peptide and steroidal-like activity, uses thereof and methods of production.

  本发明提供了新的、有用的植物来源四环素化合物衍生物，具有类固醇样活性，在某些情况下同时具有氨基酸/寡肽和类固醇样活性，以及其使用和生产方法。
• BLOOD FLOW IMPROVER AND COSMETIC
  申请人：POLA CHEMICAL INDUSTRIES, INC.

  公开号：EP0740930A1

  公开（公告）日：1996-11-06

  A steroid derivative is used as a blood flow amount-improving agent, which is blended with a cosmetic preferably in a ratio of 0.000001 to 10 % by weight with respect to a total amount of the cosmetic.

  一种类固醇衍生物可用作血流量促进剂，它与化妆品的混合比例最好为化妆品总量的 0.000001 至 10%（重量比）。
• Ecdysterone Compounds
  申请人：Kramer Ronald

  公开号：US20110021474A1

  公开（公告）日：2011-01-27

  An ecdysterone compound is described. An ecdysterone compound may include ecdysterone and decanoic acid. An ecdysterone compound may further include ecdysterone and isobutyric acid. An ecdysterone compound may comprise a physiologically active salt or ester of ecdysterone. An ecdysterone compound may further comprise a physiologically active salt or ester of decanoic acid. Alternatively, an ecdysterone compound may include a physiologically active salt or ester of isobutyric acid.
• METHODS AND COMPOSITIONS COMPRISING STEROID HONEY BEE FEEDING INHIBITORS
  申请人：Iowa State University Research Foundation, Inc.

  公开号：US20160309720A1

  公开（公告）日：2016-10-27

  Applicants have discovered novel steroid feeding inhibitors for Apis sp. that can be used in connection with traditional insecticide, pesticide, fungicide or other pest management protocols. The rapid decline of Apis sp. is devastating to the many crops which rely upon the bees, particularly honey bees ( Apis melliofera ) for pollination. Further it has been postulated that colony collapse disorder, may be the result of unintended ingestion by honey bees of insecticide, pesticide, fungicide compositions applied to nearby feeding sources for the bees. Thus, honey bee feeding inhibitors can be used in a pest management system to prevent unintended consequences to honey bees.
• US5976515A
  申请人：——

  公开号：US5976515A

  公开（公告）日：1999-11-02