N,N-diisopropyl-N',N',N'',N''-tetramethylphosphorous triamide | 502922-89-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-diisopropyl-N',N',N'',N''-tetramethylphosphorous triamide
• 英文别名: bis(dimethylamino)(diisopropylamino)phosphine；N-[bis(dimethylamino)phosphanyl]-N-propan-2-ylpropan-2-amine
• CAS: 502922-89-6
• 化学式: C₁₀H₂₆N₃P
• 分子量: 219.31
• InChiKey: ZRZVDNTUZSZQPL-UHFFFAOYSA-N

物化性质

• 沸点：
  235.4±9.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N,N-diisopropyl-N',N',N'',N''-tetramethylphosphorous triamide 、 间苯二酚 生成 3-N,3-N,11-N,11-N-tetramethyl-2,4,10,12-tetraoxa-3,11-diphosphatricyclo[11.3.1.15,9]octadeca-1(17),5(18),6,8,13,15-hexaene-3,11-diamine
  参考文献：
  名称：

  摘要：

  Reaction of resorcinol with phosphorous triamides containing various aliphatic radicals was studied. The preferential cleavage from phosphorus of the diisopropylamino group compared with the less bulky dimethylamino group was observed for the first time. It was shown that resorcinol is easily phosphorylated under mild conditions independent of the nature of substituent on nitrogen, but sterically hindered bulky radicals on nitrogen slow down phenolysis not only of the first, but also of the second amido group.

  DOI：

  10.1023/a:1020807208325
• 作为产物：
  描述：

  二异丙胺 在 三乙胺 、 三氯化磷 作用下， 以 正己烷 为溶剂， 反应 24.0h， 生成 N,N-diisopropyl-N',N',N'',N''-tetramethylphosphorous triamide
  参考文献：
  名称：

  摘要：

  Reaction of resorcinol with phosphorous triamides containing various aliphatic radicals was studied. The preferential cleavage from phosphorus of the diisopropylamino group compared with the less bulky dimethylamino group was observed for the first time. It was shown that resorcinol is easily phosphorylated under mild conditions independent of the nature of substituent on nitrogen, but sterically hindered bulky radicals on nitrogen slow down phenolysis not only of the first, but also of the second amido group.

  DOI：

  10.1023/a:1020807208325

文献信息

• ——
  作者：E. E. Nifant'ev、S. V. Suvorkin、E. N. Rasadkina、O. V. Selyutina、A. V. Shishin

  DOI：10.1023/a:1020807208325

  日期：——

  Reaction of resorcinol with phosphorous triamides containing various aliphatic radicals was studied. The preferential cleavage from phosphorus of the diisopropylamino group compared with the less bulky dimethylamino group was observed for the first time. It was shown that resorcinol is easily phosphorylated under mild conditions independent of the nature of substituent on nitrogen, but sterically hindered bulky radicals on nitrogen slow down phenolysis not only of the first, but also of the second amido group.