4-methoxy-N-methyl-1-naphthamide | 99934-65-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-methoxy-N-methyl-1-naphthamide
• 英文别名: 4-methoxy-N-methylnaphthalene-1-carboxamide
• CAS: 99934-65-3
• 化学式: C₁₃H₁₃NO₂
• mdl: MFCD24389106
• 分子量: 215.252
• InChiKey: CPIZGAGIZIZVDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.153
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2,2-trifluoroethyl(mesityl)iodonium trifluoromethanesulfonate 、 4-methoxy-N-methyl-1-naphthamide 在 palladium diacetate 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以60 %的产率得到4-methoxy-N-methyl-8-(2,2,2-trifluoroethyl)-1-naphthamide
  参考文献：
  名称：

  钯催化 C−H 活化的萘 C8-氟烷基化和 C8-氟烯基化

  摘要：

  采用碘鎓盐作为偶联伙伴，成功实现了萘衍生物的直接钯催化C8-氟烷基化和C8-氟烯基化。该反应表现出完全的 C8 区域选择性，并且多种羰基被确定为有效的导向基团。

  DOI：

  10.1002/ejoc.202400194
• 作为产物：
  描述：

  环己-1,3-二烯-5-炔 、 N-methyl-6-methoxy-2-(1H)-pyridone 以 氯仿 、 丙酮 为溶剂， 反应 4.0h， 以37%的产率得到4-methoxy-N-methyl-1-naphthamide
  参考文献：
  名称：

  Reactions of 1-unsubstituted tautomeric 2-pyridones with benzyne.

  摘要：

  1-未取代的2-吡啶酮与苯炔的反应生成了Diels-Alder加成产物5, 6-苯并-2-氮杂巴雷ланы-3 (2H)-酮，同时生成了大量的迈克尔型加成产物2-苯氧基吡啶。

  DOI：

  10.1248/cpb.33.2313

文献信息

• INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS
  申请人：Sekisui Chemical Co., Ltd.

  公开号：EP3202737A1

  公开（公告）日：2017-08-09

  The present invention aims to provide an interlayer film for laminated glass which prevents a double image phenomenon in a specific area of laminated glass and enables display of high contrast images at a luminance within a certain range. The present invention also aims to provide a laminated glass including the interlayer film for laminated glass. The present invention relates to an interlayer film for laminated glass, having a multilayer structure including a luminescent layer and a resin layer on at least one surface of the luminescent layer. The luminescent layer contains a thermoplastic resin, a plasticizer, and a luminescent material. The resin layer contains a thermoplastic resin and a plasticizer. The interlayer film for laminated glass has a wedge-shaped cross-sectional shape. The luminescent layer has a difference between the maximum thickness and the minimum thickness of 100 µm or less.

  本发明旨在提供一种夹层玻璃用中间膜，它能防止夹层玻璃特定区域出现重影现象，并能在一定亮度范围内显示高对比度图像。本发明还旨在提供一种夹层玻璃，其中包括用于夹层玻璃的中间膜。本发明涉及一种夹层玻璃用中间膜，它具有多层结构，包括发光层和发光层至少一个表面上的树脂层。发光层包含热塑性树脂、增塑剂和发光材料。树脂层包含热塑性树脂和增塑剂。夹层玻璃用中间膜的横截面形状为楔形。发光层的最大厚度与最小厚度之差不超过 100 微米。
• THERMOPLASTIC FILM AND LAMINATED GLASS
  申请人：SEKISUI CHEMICAL CO., LTD.

  公开号：EP3943295A1

  公开（公告）日：2022-01-26

  A thermoplastic film 10 is a thermoplastic film comprising a light-emitting layer 11, wherein the light-emitting layer 11 comprises a thermoplastic resin and a light-emitting material that emits light by being irradiated with excitation light, and a change in yellowness of laminated glass obtained by bonding two sheets of clear glass in accordance with JIS R 3211(1998) having a thickness of 2.5 mm with the thermoplastic film interposed therebetween after conducting a light resistance test for 2000 hours based on JIS R3205 2005 is 4 or less. The present invention provides a thermoplastic film comprising a light-emitting material, in which the emission intensity is unlikely to lower even when the thermoplastic film is exposed to ultraviolet rays for a long period of time.

  一种热塑性薄膜10是一种包含发光层11的热塑性薄膜，其中发光层11由热塑性树脂和发光材料组成，该发光材料通过被激发光照射而发光，并且在根据JIS R3205 2005进行2000小时耐光性测试后，将两片厚度为2.5毫米、中间夹有热塑性薄膜的符合JIS R 3211(1998)的透明玻璃粘合而得到的夹层玻璃的黄度变化为4或以下。本发明提供了一种包含发光材料的热塑性薄膜，即使该热塑性薄膜长期暴露在紫外线下，其发光强度也不会降低。
• Interlayer film for laminated glass, and laminated glass
  申请人：SEKISUI CHEMICAL CO., LTD.

  公开号：US10562276B2

  公开（公告）日：2020-02-18

  The present invention aims to provide an interlayer film for laminated glass which prevents a double image phenomenon in a specific area of laminated glass and enables display of high contrast images at a luminance within a certain range. The present invention also aims to provide a laminated glass including the interlayer film for laminated glass. The present invention relates to an interlayer film for laminated glass, having a multilayer structure including a luminescent layer and a resin layer on at least one surface of the luminescent layer. The luminescent layer contains a thermoplastic resin, a plasticizer, and a luminescent material. The resin layer contains a thermoplastic resin and a plasticizer. The interlayer film for laminated glass has a wedge-shaped cross-sectional shape. The luminescent layer has a difference between the maximum thickness and the minimum thickness of 100 μm or less.

  本发明旨在提供一种夹层玻璃用中间膜，它能防止夹层玻璃特定区域出现重影现象，并能在一定亮度范围内显示高对比度图像。本发明还旨在提供一种夹层玻璃，其中包括用于夹层玻璃的中间膜。本发明涉及一种夹层玻璃用中间膜，它具有多层结构，包括发光层和发光层至少一个表面上的树脂层。发光层包含热塑性树脂、增塑剂和发光材料。树脂层包含热塑性树脂和增塑剂。夹层玻璃用中间膜的横截面形状为楔形。发光层的最大厚度与最小厚度之差不超过 100 微米。
• KUZUYA, MASAYUKI;NOGUCHI, AKIHIRO;KAMIYA, SHOJI;OKUDA, TAKACHIYO, CHEM. AND PHARM. BULL., 1985, 33, N 6, 2313-2322
  作者：KUZUYA, MASAYUKI、NOGUCHI, AKIHIRO、KAMIYA, SHOJI、OKUDA, TAKACHIYO

  DOI：——

  日期：——
• Fragment Ligated Inhibitors Selective for the Polo Box Domain of PLK1
  申请人：McInnes Campbell

  公开号：US20120202970A1

  公开（公告）日：2012-08-09

  Methods for developing non-peptidic inhibitors that target the polo-box domain of PLK1 proteins are described. Methods include developing structure activity relationships for peptidic inhibitors followed by development of non-peptide fragment alternatives for portions of the peptide inhibitors. The non-peptide fragment can provide similar structure activity relationship as the replaced peptide. Fragment alternatives to key binding determinants are identified in an iterative computational and synthetic process facilitated through understanding of the peptide structure-activity relationships. The approach is informed by peptide structure-activity data obtained through synthesis and testing of truncated and mutated analogs of known PBD binding motifs.