choline octanoate | 15403-60-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: choline octanoate
• 英文别名: Capryloylcholine；trimethyl(2-octanoyloxyethyl)azanium
• CAS: 15403-60-8
• 化学式: C₁₃H₂₈NO₂
• 分子量: 230.371
• InChiKey: AKYPZHWYYXDGEW-UHFFFAOYSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  辛酸 、 氯化胆碱 在 Candida antarctica lipase B 作用下， 以 甘油 为溶剂， 生成 choline octanoate
  参考文献：
  名称：

  Development of a lipase-mediated epoxidation process for monoterpenes in choline chloride-based deep eutectic solvents

  摘要：

  当代工业过程中的化学合成主要使用有机溶剂进行，这些溶剂对人类和环境都具有潜在危险。

  DOI：

  10.1039/c7gc01127j

文献信息

• Curable silicone resin composition and reactive silicon compounds
  申请人：——

  公开号：US20030130389A1

  公开（公告）日：2003-07-10

  A curable silicone resin composition comprises (A) an uncured silicone resin having units of the formula (R*) a (R) b SiO (4−a−b)/2 , where each R* is a functional group capable of reacting with Si—OH and/or Si-alkoxy groups and each R is a nonfunctional monovalent hydrocarbon group, a+b is from 1.0 to 3.0 and each molecule of uncured silicone resin contains an average of at least two groups R*, and (B) a silanol or hydrolysable compound of the formula (I) where R′ represents a hydroxyl group or a hydrolysable group; each R″ represents hydrogen, a monovalent hydrocarbon which optionally is substituted, or a group within the above definition of R′; and Ar is a substantially nonflexible linkage including at least one para-arylene moiety, so that the groups (R′) 2 R″Si— are spatially separated.

  一种可治愈的硅树脂组合物包括(A)未固化的硅树脂，其具有式(R*)a(R)bSiO(4−a−b)/2的单元，其中每个R*是能够与Si—OH和/或Si-烷氧基反应的功能性基团，每个R是非功能性单价碳氢基团，a+b为1.0至3.0，每个未固化的硅树脂分子含有平均至少两个R*基团；以及(B)式(I)的硅醇或可水解化合物，其中R'代表羟基或可水解基团；每个R"代表氢、一价碳氢基团（可选地被取代）或上述R'定义内的基团；Ar是包括至少一个对位芳基单元的实质上非柔性连接，以使得(R')2R"Si—基团在空间上分离。
• Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
  申请人：Merck & Co., Inc.

  公开号：EP0214898A2

  公开（公告）日：1987-03-18

  Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.

  胆碱酯可作为药物吸收促进剂，用于促进鼻腔、口腔和阴道吸收不良的药物。
• Pharmaceutical composition containing choline ester salts for enhancing gastrointestinal tract absorption
  申请人：Merck & Co., Inc.

  公开号：EP0206947A2

  公开（公告）日：1986-12-30

  Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.

  胆碱酯盐可作为口服和直肠给药的药物吸收促进剂。
• Method for making rubber-modified rigid silicone resins and composites produced therefrom
  申请人：DOW CORNING CORPORATION

  公开号：EP0850998A2

  公开（公告）日：1998-07-01

  Rubber-modified rigid silicone resins and method of producing are disclosed and claimed herein. These resins are the copolymerized reaction product of (A) an organosilicon composition selected from the group consisting (I) an organosilicone resin, (II) hydrolyzable precursors of (I), and hydrolyzate(s) of (II) and (B) a silicone rubber. The resulting rubber-modified rigid silicone resins of our invention show remarkably high fracture toughness, KIc and critical strain energy release rate GIc.

  本文公开了橡胶改性硬硅树脂及其生产方法。这些树脂是(A)选自(I)有机硅树脂、(II)(I)的可水解前体和(II)的水解物组的有机硅组合物与(B)硅橡胶的共聚反应产物。本发明的橡胶改性硬硅树脂具有极高的断裂韧性 KIc 和临界应变能释放率 GIc。
• Condensation reaction curable silesquioxane resin composition and methods for the synthesis and cure thereof
  申请人：DOW CORNING CORPORATION

  公开号：EP1074574A1

  公开（公告）日：2001-02-07

  A condensation reaction curable silsesquioxane resin composition and methods for its preparation and cure are disclosed. By modifying the silsesquioxane resin with a silyl-terminated hydrocarbon, such as a silphenylene, the resulting silsesquioxane resin has improved strength and toughness without significant loss of modulus.

  本发明公开了一种可缩合反应固化的硅倍半氧烷树脂组合物及其制备和固化方法。通过用硅基封端碳氢化合物（如硅亚苯基）改性硅倍半氧烷树脂，所得到的硅倍半氧烷树脂的强度和韧性得到了提高，而模量却没有明显下降。