dibutyl-tetradecyl-amine | 198066-94-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: dibutyl-tetradecyl-amine
• 英文别名: 1-Dibutylamino-tetradecan；Dibutyl-tetradecyl-amin；N,N-Dibutyl-1-tetradecanamine；N,N-dibutyltetradecan-1-amine
• CAS: 198066-94-3
• 化学式: C₂₂H₄₇N
• 分子量: 325.622
• InChiKey: LLZGUAIXZXPTAR-UHFFFAOYSA-N

物化性质

• 沸点：
  178-180 °C(Press: 3 Torr)
• 密度：
  0.8046 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  9.4
• 重原子数：
  23
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  dibutyl-tetradecyl-amine 、 溴乙酸乙酯 生成 dibutyl-carboxymethyl-tetradecyl-ammonium betaine
  参考文献：
  名称：

  Capillary active compounds and process of preparing them

  摘要：

  公开号：

  US02313573A1
• 作为产物：
  描述：

  溴代十四烷 、 二正丁胺 生成 dibutyl-tetradecyl-amine
  参考文献：
  名称：

  Massie, Iowa State College Journal of Science, 1946, vol. 21, p. 44

  摘要：

  DOI：

文献信息

• CONTACT-KILLING, QAC FUNCTIONALIZED THERMOPLASTIC POLYURETHANE FOR CATHETER APPLICATIONS
  申请人：THE UNIVERSITY OF AKRON

  公开号：US20190106525A1

  公开（公告）日：2019-04-11

  In various embodiments, the present invention provides a functionalized thermoplastic polyurethane (TPU) containing bulk incorporated or surface-grafted quaternary ammonium compounds (QAC)s for contact-killing of a variety of microbes, where the QACs are on the surface of TPU to provide a sterile surface material that prevents bacteria commonly involved in device-associated infections (DAIs) from proliferating. The functionalized TPUs of the present invention can be formed into a wide variety of 3-dimensional shapes, such as catheters, medical tubing, laryngeal or tracheal stents, sutures, prosthetics, wound dressings, and/or a coating for medical devices and contains the residue of either a QAC containing diol monomer or an alkene functional diol monomer, which then allows the TPU to be functionalized with a QAC containing disulfide or free thiol compound, to form a quaternary ammonium functionalized thermoplastic polyurethane compound having antimicrobial properties for use in medical devices.

  在各种实施方式中，本发明提供了一种功能化的热塑性聚氨酯（TPU），其中包含大量引入或表面接枝的季铵化合物（QAC），用于接触杀灭多种微生物，其中QAC位于TPU表面，以提供一种无菌表面材料，防止通常涉及设备相关感染（DAIs）的细菌繁殖。本发明的功能化TPU可以形成多种三维形状，例如导管、医疗管、喉部或气管支架、缝合线、假体、伤口敷料和/或医疗设备的涂层，并包含含有二醇单体或烯功能二醇单体的QAC残留物，这使得TPU可以用含有二硫键或自由巯基化合物的QAC进行功能化，以形成具有用于医疗设备的抗菌性能的季铵功能化热塑性聚氨酯化合物。
• Polyester polyol-containing polyurethane systems having improved hydrolytic stability
  申请人：EVONIK DEGUSSA GMBH

  公开号：US10023680B2

  公开（公告）日：2018-07-17

  An isocyanate reactive composition for making a polyurethane foam includes a tertiary amine urethane catalyst comprising a di(C1-C4)alkyl fatty alkyl amine and a polyester polyol. The use of one or more of fatty alkyl tertiary amine serves to reduce hydrolysis of the polyester polyol in the isocyanate reactive composition.

  一种用于制造聚氨酯泡沫的异氰酸酯反应组合物包括由二（C1-C4）烷基脂肪烷基胺和聚酯多元醇组成的叔胺聚氨酯催化剂。使用一种或多种脂肪烷基叔胺可减少异氰酸酯反应组合物中聚酯多元醇的水解。
• Contact-killing, QAC functionalized thermoplastic polyurethane for catheter applications
  申请人：THE UNIVERSITY OF AKRON

  公开号：US11155668B2

  公开（公告）日：2021-10-26

  In various embodiments, the present invention provides a functionalized thermoplastic polyurethane (TPU) containing bulk incorporated or surface-grafted quaternary ammonium compounds (QAC)s for contact-killing of a variety of microbes, where the QACs are on the surface of TPU to provide a sterile surface material that prevents bacteria commonly involved in device-associated infections (DAIs) from proliferating. The functionalized TPUs of the present invention can be formed into a wide variety of 3-dimensional shapes, such as catheters, medical tubing, laryngeal or tracheal stents, sutures, prosthetics, wound dressings, and/or a coating for medical devices and contains the residue of either a QAC containing diol monomer or an alkene functional diol monomer, which then allows the TPU to be functionalized with a QAC containing disulfide or free thiol compound, to form a quaternary ammonium functionalized thermoplastic polyurethane compound having antimicrobial properties for use in medical devices.

  在各种实施例中，本发明提供了一种功能化热塑性聚氨酯（TPU），其中含有用于接触杀灭各种微生物的批量掺入或表面接枝的季铵化合物（QAC），其中 QAC 位于 TPU 表面，以提供一种无菌表面材料，防止常见于设备相关感染（DAI）的细菌增殖。本发明的功能化热塑性聚氨酯可制成各种三维形状，如导管、医用管道、喉或气管支架、缝合线、假肢、伤口敷料和/或医疗器械涂层，并含有含 QAC 的二元醇单体或烯功能二元醇单体的残留物、这样，热塑性聚氨酯就可以与含有二硫化物或游离硫醇化合物的 QAC 进行官能化，形成具有抗菌特性的季铵官能化热塑性聚氨酯化合物，用于医疗器械。
• Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds
  申请人：Panchalingam Vaithilingam

  公开号：US20050081714A1

  公开（公告）日：2005-04-21

  A method and a quaternary ammonium or phosphonium composition used therein for inhibiting retarding, mitigating, reducing, controlling and/or delaying formation of hydrocarbon hydrates or agglomerates of hydrates. The method may be applied to prevent or reduce or mitigate plugging of conduits, pipes, transfer lines, valves, and other places or equipment where hydrocarbon hydrate solids may form under the conditions. At least one quaternary ammonium or phosphonium compound is added into the process stream, where the compound may be mixed with another compound selected from other amino alcohols, esters, quaternary ammonium, phosphonium or sulphonium salts, betaines, amine oxides, amides, simple amine salts, and combinations thereof.

  一种抑制、延缓、减轻、减少、控制和/或延迟碳氢化合物水合物或水合物团聚体形成的方法及其中使用的季铵或鏻组合物。该方法可用于防止或减少或减轻导管、管道、传输线、阀门和其他在条件下可能形成烃水合物固体的地方或设备的堵塞。将至少一种季铵或鏻化合物加入工艺流中，该化合物可与选自其他氨基醇、酯、季铵盐、鏻盐或锍盐、甜菜碱、胺氧化物、酰胺、单胺盐及其组合的另一种化合物混合。
• Methods for inhibiting hydrate blockage in oil and gas pipelines using amino alcohols and ester compounds
  申请人：Panchalingam Vaithilingam

  公开号：US20050085396A1

  公开（公告）日：2005-04-21

  A method and an ester composition used therein for inhibiting, retarding, mitigating, reducing, controlling and/or delaying formation of hydrocarbon hydrates or agglomerates of hydrates. The method may be applied to prevent or reduce or mitigate plugging of conduits, pipes, transfer lines, valves, and other places or equipment where hydrocarbon hydrate solids may form under the conditions. At least one ester compound is added into the process stream, where the compound may be mixed with another compound selected from other amino alcohols, esters, quaternary ammonium, phosphonium or sulphonium salts, betaines, amine oxides, amides, simple amine salts, and combinations thereof.

  一种用于抑制、延缓、减轻、减少、控制和/或延迟碳氢化合物水合物或水合物团聚体形成的方法及其所用的酯组合物。该方法可用于防止或减少或减轻导管、管道、输送线、阀门和其他在条件下可能形成碳氢化合物水合物固体的地方或设备的堵塞。将至少一种酯类化合物加入工艺流中，该化合物可与选自其他氨基醇、酯、季铵盐、鏻盐或锍盐、甜菜碱、胺氧化物、酰胺、单胺盐及其组合的另一种化合物混合。