Bis[1-(3-formyl-2-hydroxynaphthalen-1-yl)naphthalen-2-yl] hexanedioate | 1002101-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Bis[1-(3-formyl-2-hydroxynaphthalen-1-yl)naphthalen-2-yl] hexanedioate
• 英文别名: bis[1-(3-formyl-2-hydroxynaphthalen-1-yl)naphthalen-2-yl] hexanedioate
• CAS: 1002101-65-6
• 化学式: C₄₈H₃₄O₈
• 分子量: 738.793
• InChiKey: CCTDFCCHZMEXPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.3
• 重原子数：
  56
• 可旋转键数：
  13
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  127
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  Bis[1-(3-formyl-2-hydroxynaphthalen-1-yl)naphthalen-2-yl] hexanedioate 、 (1R,2R)-(+)-1,2-环己二胺 L-酒石酸盐 在 potassium carbonate 作用下， 以 乙醇 、 水 为溶剂， 反应 0.08h， 以96%的产率得到(41R,46R)-57,58-dihydroxy-12,19-dioxa-40,47-diazadecacyclo[47.7.1.130,38.02,11.03,8.020,29.023,28.031,36.041,46.051,56]octapentaconta-1(57),2(11),3,5,7,9,20(29),21,23,25,27,30(58),31,33,35,37,39,47,49,51,53,55-docosaene-13,18-dione
  参考文献：
  名称：

  Synthesis of new binol based [1+1] macrocyclic chiral manganese(III) Schiff bases as catalysts for asymmetric epoxidation

  摘要：

  A series of new chiral binol based [1+1] macrocyclic Schiff bases have been synthesized in high yields in short reaction times via cyclo-condensation of dialdehydes with long tethers and chiral diamines. Macrocyclic Mn(salen) complexes containing N2O2 salen units incorporated with spacers of increased tether lengths were synthesized and characterized. The newly synthesized catalyst system was successfully employed for the enantioselective epoxidation of unfunctionalized olefins with high yields and good enantioselectivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2013.04.017
• 作为产物：
  描述：

  (R(a))-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl-3-carbaldehyde 在 盐酸 、 4-二甲氨基吡啶 作用下， 以 甲醇 、 二氯甲烷 、 水 为溶剂， 反应 5.25h， 生成 Bis[1-(3-formyl-2-hydroxynaphthalen-1-yl)naphthalen-2-yl] hexanedioate
  参考文献：
  名称：

  Synthesis of new binol based [1+1] macrocyclic chiral manganese(III) Schiff bases as catalysts for asymmetric epoxidation

  摘要：

  A series of new chiral binol based [1+1] macrocyclic Schiff bases have been synthesized in high yields in short reaction times via cyclo-condensation of dialdehydes with long tethers and chiral diamines. Macrocyclic Mn(salen) complexes containing N2O2 salen units incorporated with spacers of increased tether lengths were synthesized and characterized. The newly synthesized catalyst system was successfully employed for the enantioselective epoxidation of unfunctionalized olefins with high yields and good enantioselectivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2013.04.017

文献信息

• A Facile Synthesis of New Chiral [1+1] Macrocyclic Schiff Bases
  作者：Paulsamy Suresh、Sankareswaran Srimurugan、Hari N. Pati

  DOI：10.1246/cl.2007.1332

  日期：2007.11.5

  A series of new chiral [1+1] macrocyclic Schiff bases have been synthesized in high yields and short reaction times from cyclocondensation of dialdehydes with long tethers and chiral diamines. The ...

  通过二醛与长链和手性二胺的环缩合反应，以高产率和短反应时间合成了一系列新的手性 [1+1] 大环席夫碱。这 ...
• Synthesis of new binol based [1+1] macrocyclic chiral manganese(III) Schiff bases as catalysts for asymmetric epoxidation
  作者：Paulsamy Suresh、Sankareswaran Srimurugan、Ravindra T. Dere、R. Venkat Ragavan、Vadiraj Suphala Gopinath

  DOI：10.1016/j.tetasy.2013.04.017

  日期：2013.6

  A series of new chiral binol based [1+1] macrocyclic Schiff bases have been synthesized in high yields in short reaction times via cyclo-condensation of dialdehydes with long tethers and chiral diamines. Macrocyclic Mn(salen) complexes containing N2O2 salen units incorporated with spacers of increased tether lengths were synthesized and characterized. The newly synthesized catalyst system was successfully employed for the enantioselective epoxidation of unfunctionalized olefins with high yields and good enantioselectivity. (C) 2013 Elsevier Ltd. All rights reserved.