3,9-bis-(4-dimethylamino-phenyl)-2,4,8,10-tetraoxa-spiro[5.5]undecane | 101325-43-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3,9-bis-(4-dimethylamino-phenyl)-2,4,8,10-tetraoxa-spiro[5.5]undecane
• 英文别名: 3,9-Bis-(4-dimethylamino-phenyl)-2,4,8,10-tetraoxa-spiro[5.5]undecan；4,4'-(2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diyl)bis(N,N-dimethylaniline)；4-[3-[4-(dimethylamino)phenyl]-2,4,8,10-tetraoxaspiro[5.5]undecan-9-yl]-N,N-dimethylaniline
• CAS: 101325-43-3
• 化学式: C₂₃H₃₀N₂O₄
• 分子量: 398.502
• InChiKey: SWYONIKMNPDIHD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  季戊四醇 、 对二甲氨基苯甲醛 在 montmorillonite K-10 作用下， 以 甲苯 为溶剂， 反应 8.0h， 以94%的产率得到3,9-bis-(4-dimethylamino-phenyl)-2,4,8,10-tetraoxa-spiro[5.5]undecane
  参考文献：
  名称：

  Montmorillonite Clays Catalysis. Part 12.1 An Efficient and Practical Procedure for Synthesis of Diacetals from 2,2-Bis(hydroxymethyl)propane-1,3-diol with Carbonyl Compounds

  摘要：

  用 aldehydes 和 ketones 制备 2,2-bis(hydroxymethyl)propane-1,3-diol 的二缩醛，在回流的苯或甲苯中以蒙脱石粘土作为催化剂，产率良好至优秀。

  DOI：

  10.1039/a803046d

文献信息

• Synthesis of Diacetals from Aldehydes and Ketones with Pentaerythritol Catalyzed by Silica Sulfate Under Microwave Irradiation
  作者：Tong‐Shou Jin、Huan‐Xin Wang、Kai‐Fang Wang、Tong‐Shuang Li

  DOI：10.1081/scc-200026658

  日期：2004.1.1

  Abstract The synthesis of diacetals from pentaerythritol with aldehydes and ketones is carried out under microwave irradiation in 80–98% yields with silica sulfate as catalyst.

  摘要 季戊四醇与醛和酮合成二缩醛是在微波辐射下以硫酸硅为催化剂以 80-98% 的产率进行的。
• A Green Recyclable Poly(4-Vinylpyridine)-Supported Copper Iodide Nanoparticle Catalyst for the Chemoselective Synthesis of Pentaerythritol Diacetals from Aromatic Aldehydes
  作者：Jalal Albadi、Nasir Iravani、Farhad Shirini、Farzaneh Dehghan

  DOI：10.3184/174751912x13460806564901

  日期：2012.10

  Poly(4-vinylpyridine)-supported copper(I) iodide nanoparticles have been used as an efficient, green recyclable catalyst for the chemoselective synthesis of pentaerythritol diacetals from aromatic aldehydes and pentaerythritol under solvent-free conditions. This catalyst was reused six times without any loss of its activity.

  聚（4-乙烯基吡啶）负载的碘化铜（I）纳米粒子已被用作一种高效的绿色可回收催化剂，用于在无溶剂条件下从芳香醛和季戊四醇化学选择性合成季戊四醇二缩醛。该催化剂可重复使用六次，其活性没有任何损失。
• A Practical and Efficient Procedure for Preparation of Diacetals from 2,2-Bis(hydroxymethyl)propane-1,3-diol with Aldehydes and Ketones Catalysed by Anhydrous Ferrous Sulfate
  作者：Tong-Shou Jin、Yan-Ran Ma、Tong-Shuang Li、Jian-Xin Wang

  DOI：10.1039/a900025i

  日期：——

  Synthesis of diacetals in excellent yields from aldehydes and ketones with 2,2-bis(hydroxymethyl)propane-1,3-diol is carried out in refluxing benzene or toluene with anhydrous ferrous sulfate as catalyst.

  在回流的苯或甲苯中，以无水硫酸亚铁为催化剂，由醛和酮与 2,2-双（羟甲基）丙烷-1,3-二醇以优异的收率合成二缩醛。
• Synthesis Of Diacetals By Condensation Of Carbonyl Compounds With Bis(Hydrox Ymethyl)-1,3-Propanediol Catalysed By Expansive Graphite
  作者：Tong-Shou Jin、Tong-Shuang Li、Zhan-Hui Zhang、Yan-Jun Yuan

  DOI：10.1080/00397919908086141

  日期：1999.5

  Synthesis of diacetals from 2,2-bis(hydroxymethyl)-1,3-propanediol with aldehydes and ketones under catalysis of expansive graphite in refluxing benzene or toluene in good to excellent yield has been described.
• xxx, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000, vol. 39, # 11, p. 858 - 859
  作者：xxx

  DOI：——

  日期：——