Thiovanillinsaeurediethylamid | 24115-07-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: Thiovanillinsaeurediethylamid
• 英文别名: (4E)-4-[diethylamino(mercapto)methylidene]-2-methoxy-1-cyclohexa-2,5-dienone；N,N-diethyl-4-hydroxy-3-methoxybenzenecarbothioamide
• CAS: 24115-07-9
• 化学式: C₁₂H₁₇NO₂S
• 分子量: 239.338
• InChiKey: PHZWCFWNUOZRND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  64.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE
  申请人：Bezwada Rao S.

  公开号：US20090105352A1

  公开（公告）日：2009-04-23

  This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.

  这项发明涉及发现的功能化三氯生单体和寡聚体，当它们被纳入医疗设备的基质中，或作为涂层的一部分应用于医疗设备和/或消费品时，可以延长医疗设备和/或消费品的抗菌性能持续时间。
• CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS
  申请人：Bezwada Rao S.

  公开号：US20090076174A1

  公开（公告）日：2009-03-19

  The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically active molecules have a controllable degradation profile. The hydrolytic degradation of oligomers of the present invention releases the biologically active compound as such with no change in native chemical structure.

  本发明涉及可生物降解的多臂寡聚体的发现，其中这些寡聚体的末端基团已经被生物活性分子功能化。末端功能化生物活性分子的多臂寡聚体具有可控的降解特性。本发明的寡聚体的水解降解会释放出生物活性化合物，其原有的化学结构不会发生改变。
• CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS
  申请人：Bezwada Rao S.

  公开号：US20120010284A1

  公开（公告）日：2012-01-12

  The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically active molecules have a controllable degradation profile. The hydrolytic degradation of oligomers of the present invention releases the biologically active compound as such with no change in native chemical structure.
• US8053591B2
  申请人：——

  公开号：US8053591B2

  公开（公告）日：2011-11-08
• US8026285B2
  申请人：——

  公开号：US8026285B2

  公开（公告）日：2011-09-27