1-(Dimethylamino)-N-methylcyclopentanemethanamine | 363626-94-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-(Dimethylamino)-N-methylcyclopentanemethanamine
• 英文别名: N,N-dimethyl-1-(methylaminomethyl)cyclopentan-1-amine
• CAS: 363626-94-2
• 化学式: C₉H₂₀N₂
• mdl: MFCD09041471
• 分子量: 156.27
• InChiKey: JFMXHJHSMDCMCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
  申请人：Gilead Sciences, Inc.

  公开号：EP3294732B1

  公开（公告）日：2019-09-25
• [EN] BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE<br/>[FR] COMPOSÉS DE CARBOXYMIDAMIDE DE BENZIMIDAZOLE ET D'IMADAZOPYRIDINE PRÉSENTANT UNE ACTIVITÉ EN TANT QU'INHIBITEURS DE L'INDOLÉAMINE 2,3-DIOXYGÉNASE
  申请人：GILEAD SCIENCES INC

  公开号：WO2016186967A1

  公开（公告）日：2016-11-24

  The present disclosure provides indoleamine 2,3 -dioxygenase 1 (IDO1) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and R1 are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.