2,4,6-trimethyl-2-oxo-1,3,2-dioxaphosphorinane | 127380-58-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: 2,4,6-trimethyl-2-oxo-1,3,2-dioxaphosphorinane
• 英文别名: 2,4,6-trimethyl-[1,3,2]dioxaphosphorinane-2-oxide；Methylphosphonsaeure-(1,3-dimethyl-propandiylester)；2,4,6-Trimethyl-[1,3,2]dioxaphosphorinan-2-oxid；2α-methyl-2β-oxo-4α,6α-dimethyl-1,3,2-dioxaphosphorinane；2,4,6-Trimethyl-1,3,2lambda5-dioxaphosphinane 2-oxide；2,4,6-trimethyl-1,3,2λ5-dioxaphosphinane 2-oxide
• CAS: 127380-58-9；61558-34-7；148152-83-4
• 化学式: C₆H₁₃O₃P
• 分子量: 164.141
• InChiKey: VQBCNGTUNIHBPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,4,6-trimethyl-2-oxo-1,3,2-dioxaphosphorinane 、 2,2-二甲基-1,3-环己烷二酮 在 正丁基锂 作用下， 生成 3-丙-2-基环己-2-烯-1-酮
  参考文献：
  名称：

  A multistep rearrangement from 2,2-disubstituted-1,3-cyclohexanediones to 3-substituted 2-cyclohexenones via phosphonate anions and its application to a formal synthesis of (.+-.)-.alpha.-acoradiene

  摘要：

  DOI：

  10.1021/jo00300a003
• 作为产物：
  描述：

  甲基膦酞二氯 、 2,4-戊二醇 以75%的产率得到2,4,6-trimethyl-2-oxo-1,3,2-dioxaphosphorinane
  参考文献：
  名称：

  固体载体合成：一种在温和条件下简便合成环状烷基膦酸盐的新方法

  摘要：

  DOI：

  10.1515/hc.2008.14.4.269

文献信息

• PROCESS FOR PRODUCING 1,2-TRANS-GLYCOSIDE COMPOUND
  申请人：Otsuka Chemical Co., Ltd.

  公开号：EP1849794A1

  公开（公告）日：2007-10-31

  In preparing a glycoside compound from (a) a furanose compound or pyranose compound, and (b) an alcohol compound, a process for preparing a glycoside compound in which glycosidic bond locates selectively trans form relative to C-2 hydroxyl group, the process comprising using a furanose compound wherein the hydroxyl at the 2-position may have a substituent protected with a group A, or a pyranose compound which may have a substituent wherein R2 and R3 are the same or different and are each alkyl having 1 to 4 carbon atoms or aryl having or not having a substituent, or R2 and R3 are combined to form alkylene having 2 to 4 carbon atoms (the alkylene may be substituted with alkyl having 1 to 4 carbon atoms, or may have intervening phenylene), and m and n are each an integer of 0 or 1.

  在从(a)呋喃糖化合物或吡喃糖化合物和(b)醇化合物制备苷化合物时，制备苷键相对于 C-2 羟基选择性地反式定位的苷化合物的工艺，该工艺包括使用呋喃糖化合物，其中 2 位的羟基可能具有被 A 基团保护的取代基，或使用吡喃糖化合物，其中可能具有取代基 其中R2和R3相同或不同，各自为具有1至4个碳原子的烷基或具有或不具有取代基的芳基，或R2和R3结合形成具有2至4个碳原子的亚烷基(该亚烷基可被具有1至4个碳原子的烷基取代，或可有中间的亚苯基)，m和n各自为0或1的整数。
• Organic Phosphorus Compounds. III. Reactions of Methanephosphonyl Dichloride with Diols¹
  作者：A. F. McKay、R. A. B. Bannard、R. O. Braun、R. L. Benness

  DOI：10.1021/ja01642a058

  日期：1954.7
• Process for Producing 1,2-Trans-Glycoside Compound
  申请人：Yamago Shigeru

  公开号：US20080177049A1

  公开（公告）日：2008-07-24

  In preparing a glycoside compound from (a) a furanose compound or pyranose compound, and (b) an alcohol compound, a process for preparing a glycoside compound in which glycosidic bond locates selectively trans form relative to C-2 hydroxyl group, the process comprising using a furanose compound wherein the hydroxyl at the 2-position may have a substituent protected with a group A, or a pyranose compound which may have a substituent wherein R 2 and R 3 are the same or different and are each alkyl having 1 to 4 carbon atoms or aryl having or not having a substituent, or R 2 and R 3 are combined to form alkylene having 2 to 4 carbon atoms (the alkylene may be substituted with alkyl having 1 to 4 carbon atoms, or may have intervening phenylene), and m and n are each an integer of 0 or 1.
• US8212013B2
  申请人：——

  公开号：US8212013B2

  公开（公告）日：2012-07-03
• US8664372B2
  申请人：——

  公开号：US8664372B2

  公开（公告）日：2014-03-04