(1R,2S,4S,6R,7R,8R,10S,11R)-6-acetyl-8-hydroxy-7,11-dimethyl-5-oxapentacyclo[8.8.0.02,7.04,6.011,16]octadeca-15,17-dien-14-one | 924910-84-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (1R,2S,4S,6R,7R,8R,10S,11R)-6-acetyl-8-hydroxy-7,11-dimethyl-5-oxapentacyclo[8.8.0.02,7.04,6.011,16]octadeca-15,17-dien-14-one
• CAS: 924910-84-9
• 化学式: C₂₁H₂₆O₄
• 分子量: 342.4
• InChiKey: UEKBPJOUDFFTMZ-BFOQGOHBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  66.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Method and compostitions for treating coronavirus infection
  申请人：PHOENIX BIOTECHNOLOGY, INC.

  公开号：US10729735B1

  公开（公告）日：2020-08-04

  A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin is used to treat viral infection.

  提供了一种治疗病毒感染的方法，例如由冠状病毒科病毒引起的病毒感染。一种至少含有齐墩果素的组合物用于治疗病毒感染。
• METHOD AND COMPOSITIONS FOR TREATING CORONAVIRUS INFECTION
  申请人：Phoenix Biotechnology, Inc.

  公开号：EP4009981A1

  公开（公告）日：2022-06-15
• Method and Compositions for Treating Coronavirus Infection
  申请人：PHOENIX BIOTECHNOLOGY, INC.

  公开号：US20220054521A1

  公开（公告）日：2022-02-24

  A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin is used to treat viral infection.
• [EN] METHOD AND COMPOSITIONS FOR TREATING GLIOBLASTOMA<br/>[FR] MÉTHODE ET COMPOSITIONS DE TRAITEMENT D'UN GLIOBLASTOME
  申请人：PHOENIX BIOTECHNOLOGY INC

  公开号：WO2021113027A1

  公开（公告）日：2021-06-10

  A method of treaing glioma is provided. A combination protocol as described herein includes radiotherapy, chemotherapy, and pharmacotherapy. Resection of the glioma is optionally included in the combination protocol. Pharmacotherapy is conducted with an oleandrin-containing composition. Treatment of glioblastoma is particularly contemplated.
• [EN] METHOD AND COMPOSITIONS FOR TREATING CORONAVIRUS INFECTION<br/>[FR] MÉTHODE ET COMPOSITIONS POUR LE TRAITEMENT D'UNE INFECTION À CORONAVIRUS
  申请人：PHOENIX BIOTECHNOLOGY INC

  公开号：WO2021201903A1

  公开（公告）日：2021-10-07

  A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin is used to treat viral infection.