dimethyl-10Z-2-oxo-10-nonadecenyl phosphonate | 146094-28-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: dimethyl-10Z-2-oxo-10-nonadecenyl phosphonate
• 英文别名: (Z)-1-dimethoxyphosphorylnonadec-10-en-2-one
• CAS: 146094-28-2
• 化学式: C₂₁H₄₁O₄P
• 分子量: 388.528
• InChiKey: RLKGNYIHROPSGJ-QXMHVHEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  26
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dimethyl-10Z-2-oxo-10-nonadecenyl phosphonate 、 Acetic acid (2R,3R,4S,5R,6R)-3,5-diacetoxy-2-acetoxymethyl-6-((E)-(2R,3S)-2,3-diacetoxy-6-oxo-hex-4-enyloxy)-tetrahydro-pyran-4-yl ester 在 氢氧化钾 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以66%的产率得到2R,3S,4E,6E,16Z-1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranylhydroxy)-2,3-di-O-acetyl-4,6,16-pentacosatrien-8-one
  参考文献：
  名称：

  Stereocontrolled synthesis of low-molecular-weight ?-O-glycosides from products of decyclization of acylated oligosaccharide glycals

  摘要：

  Low-molecular-weight beta-O-glycosides with aliphatic polyfunctional aglycones were synthesized by Horner-Emmons olefination of O-glycosylated alpha,beta-unsaturated aldehydes prepared by acid opening of the dihydropyran ring in totally acylated lactal, cellobial, and gentiobial.

  DOI：

  10.1007/bf00864541
• 作为产物：
  描述：

  油酸甲酯 、 甲基膦酸二甲酯 在 正丁基锂 作用下， 生成 dimethyl-10Z-2-oxo-10-nonadecenyl phosphonate
  参考文献：
  名称：

  Stereocontrolled synthesis of low-molecular-weight ?-O-glycosides from products of decyclization of acylated oligosaccharide glycals

  摘要：

  Low-molecular-weight beta-O-glycosides with aliphatic polyfunctional aglycones were synthesized by Horner-Emmons olefination of O-glycosylated alpha,beta-unsaturated aldehydes prepared by acid opening of the dihydropyran ring in totally acylated lactal, cellobial, and gentiobial.

  DOI：

  10.1007/bf00864541

文献信息

• Stereocontrolled synthesis of low-molecular-weight ?-O-glycosides from products of decyclization of acylated oligosaccharide glycals
  作者：A. G. Tolstikov、O. F. Prokopenko、L. V. Spirikhin、G. A. Tolstikov

  DOI：10.1007/bf00864541

  日期：1992.5

  Low-molecular-weight beta-O-glycosides with aliphatic polyfunctional aglycones were synthesized by Horner-Emmons olefination of O-glycosylated alpha,beta-unsaturated aldehydes prepared by acid opening of the dihydropyran ring in totally acylated lactal, cellobial, and gentiobial.