1,6-bisdiethylaminohexane | 7136-51-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,6-bisdiethylaminohexane
• 英文别名: tetra-N-ethyl-hexanediyldiamine；Tetra-N-aethyl-hexandiyldiamin；N,N,N',N'-tetraethyl-1,6-hexanediamine；N,N,N',N'-Tetraethylhexamethylendiamin；1,6-Bis-diethylamino-hexan；1,6-Hexanediamine, N,N,N',N'-tetraethyl-；N,N,N',N'-tetraethylhexane-1,6-diamine
• CAS: 7136-51-8
• 化学式: C₁₄H₃₂N₂
• 分子量: 228.421
• InChiKey: SRTOAFZPEOCBGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,6-bisdiethylaminohexane 在 xylene 作用下， 生成 hexa-N-ethyl-N,N'-(7,7-diethyl-7-azonia-tridecanediyl)-di-ammonium; tris iodide
  参考文献：
  名称：

  Neuromuscular Blocking Agents

  摘要：

  摘要：本文描述了两种新的NSN-三乙醇铵化合物的制备方法，分别为9-乙基-9-硫氮庚二烯双(三乙醇铵)三碘化物（二辛磺酸三乙硫碘酸盐；DOSE）和11-乙基-11-硫氮十二烯双(三乙醇铵)三碘化物（二十二磺酸三乙硫碘酸盐；DDSE）。还合成了双季铵化合物7-二氧代硫氮十三烯双(三乙醇铵碘化物)，以及NNN-三季铵化合物7:7-二乙基-7-氮杂硫氮十三烯双(三乙醇铵)三碘化物（二己杂铵三乙硫碘酸盐；DHAE）、9:9-二乙基-9-氮杂硫氮庚二烯双(三乙醇铵)三碘化物（二辛杂铵三乙硫碘酸盐；DOAE）和11:11-二乙基-11-氮杂硫氮十二烯双(三乙醇铵)三碘化物（二十二杂铵三乙硫碘酸盐；DDAE）。所有化合物在猫的腓肠肌-坐骨神经制备、大鼠和小猫的膈神经-膈肌制备，以及通过兔头下降和小鼠麻痹方法测量时均具有神经肌肉阻滞活性。二己杂铵三乙硫碘酸盐和7-二氧代硫氮十三烯双(三乙醇铵碘化物)（二己酮）表现出肌松药物样的活性；二辛磺酸三乙硫碘酸盐和二辛杂铵三乙硫碘酸盐主要表现出肌松药物样的特性，但也具有一些过渡性质，而二十二磺酸三乙硫碘酸盐和二十二杂铵三乙硫碘酸盐类似于十甲铵。在猫中，二己杂铵三乙硫碘酸盐的效力与肉豆蔻碱大致相同。观察到显著的物种差异。讨论了理论意义。

  DOI：

  10.1111/j.2042-7158.1958.tb10389.x
• 作为产物：
  描述：

  2,5-Bis-diethylaminomethyl-thiophen 在 镍 氢气 作用下， 以 乙醚 为溶剂， 生成 1,6-bisdiethylaminohexane
  参考文献：
  名称：

  Syntheses based on thiophene aldehydes Communication 3. Some diamines of the thiophene series and their reductive desulfurization

  摘要：

  DOI：

  10.1007/bf00845948

文献信息

• LITHIUM BORON FLUOROPHOSPHATE COMPLEX COMPOUND, LITHIUM BORON FLUOROPHOSPHATE-CONTAINING COMPOSITION, LITHIUM BORON FLUOROPHOSPHATE, ADDITIVE FOR LITHIUM SECONDARY BATTERY, NON-AQUEOUS ELECTROLYTIC SOLUTION FOR BATTERY, AND LITHIUM SECONDARY BATTERY
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20200148710A1

  公开（公告）日：2020-05-14

  A lithium boron fluorophosphate complex compound including a compound A that is one selected from a group of lithium boron fluorophosphates represented by Formula (I), and a compound B that is one selected from a group of compounds represented by Formulae (II) to (IX). R 0 represents a hydrocarbon group, R 1 to R 7 each independently represent a hydrogen atom or a substituent, R 8 , R 9 , R 10 , R 11 , and R 13 to R 21 each independently represent a substituent, and R 12 , R 22 , and R 23 each independently represent a divalent linking group.

  一种锂硼氟磷酸盐复合物，包括化合物A和化合物B，其中化合物A是从由式(I)表示的锂硼氟磷酸盐组中选择的一种，化合物B是从由式(II)至(IX)表示的化合物组中选择的一种。其中，R0表示一个碳氢基团，R1到R7各自独立地表示氢原子或取代基，R8、R9、R10、R11和R13到R21各自独立地表示取代基，R12、R22和R23各自独立地表示二价连接基团。
• METHOD TO MAKE A SOLID POLYMERIC PHOSPHATE AND RESINOUS COMPOSITIONS CONTAINING IT
  申请人：General Electric Company

  公开号：US20040044134A1

  公开（公告）日：2004-03-04

  Disclosed is a method for the preparation of polymeric phosphate flame retardants with a molecular weight of at least about 1500 and a softening temperature of at least about 10° C. comprising the steps of (a) reacting a phosphorus oxyhalide with a monohydroxyaromatic compound, (b) removing substantially all of any remaining phosphorus oxyhalide; (c) reacting the monoaryldichlorophosphate product with a dihydroxyaromatic compound and (d) reacting the product of step (c) with a monohydroxyaromatic compound. The solid polymeric flame retardant has a linear structure and less than 10 ppm halogen bound to phosphorus. Also disclosed are resinous compositions comprising the solid polymeric phosphate made by the method of the invention and at least one other polymeric resin.

  本发明揭示了一种制备分子量至少为约1500且软化温度至少为约10℃的聚酸酯磷系阻燃剂的方法，包括以下步骤：(a)将氧卤化磷与单羟基芳香化合物反应，(b)去除几乎所有剩余的氧卤化磷；(c)将单芳基二氯磷酸酯产物与双羟基芳香化合物反应，(d)将步骤(c)的产物与单羟基芳香化合物反应。固体聚酸酯磷系阻燃剂具有线性结构，并且磷上结合的卤素少于10ppm。本发明还揭示了由本发明方法制备的固体聚酸酯磷系阻燃剂和至少一种其他聚合物树脂组成的树脂组合物。
• 2,4-DIAMINOPYRIMIDINE DERIVATES AS PTK2- INHIBITORS FOR THE TREATMENT OF ABNORMAL CELL GROWTH
  申请人：Sapountzis Ioannis

  公开号：US20110275633A1

  公开（公告）日：2011-11-10

  The present invention encompasses compounds of general formula (1) wherein R 1 -R 3 and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.

  本发明涵盖了通式（1）中R1-R3和n的定义如权利要求1所述的化合物，适用于治疗由过度或异常细胞增殖所特征的疾病，并且它们用于制备具有上述特性的药物。
• BUFFER COMPOUNDS
  申请人：Haymore Barry L.

  公开号：US20120129240A1

  公开（公告）日：2012-05-24

  A method of buffering a chemical or biological composition, comprising adding to the composition an effective buffering amount of at least one protonated or un-protonated amine-quaternary ammonium compound having a general formula: wherein the variables R, G, n and k are as defined herein.

  一种化学或生物组成物的缓冲方法，包括向该组成物中添加至少一种质子化或非质子化的胺-季铵化合物，该化合物具有以下通式： 其中变量R、G、n和k的定义如本文所述，并且添加的量足以产生缓冲效应。
• Diaminoalkylene quaternary ammonium salts, method for their preparation and use
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0877014A2

  公开（公告）日：1998-11-11

  Diaminoalkyl quaternary ammonium salts are prepared by the reaction of alkyl halides with tertiary diamines having C2-20 primary alkyl radicals attached to nitrogen and an alkyl radical between the two nitrogen atoms in which at least three carbon atoms separate said nitrogen atoms. Said salts are preferably substantially free from corresponding diamines. They are useful as catalysts for interfacial polycarbonate preparation by the reaction of phosgene with at least one dihydroxyaromatic compound. Polycarbonate preparation using such catalysts is economical in phosgene consumption, is accompanied by a rapid conversion of chloroformate groups to desirable species and affords a product with a very low proportion of unreacted dihydroxyaromatic compound.

  二氨基烷基季铵盐是通过烷基卤化物与具有 C2-20 伯烷基的叔二胺反应制备的，叔二胺的氮上连接有 C2-20 伯烷基，两个氮原子之间有一个烷基，其中至少有三个碳原子将所述氮原子分开。所述盐类最好基本上不含相应的二胺。它们可用作催化剂，通过光气与至少一种二羟基芳香族化合物的反应制备界面聚碳酸酯。使用这种催化剂制备聚碳酸酯，光气消耗量低，氯甲酸酯基团能迅速转化为所需的物质，而且产品中未反应的二羟基芳香族化合物比例极低。