1,4-bis(3-pyridylmethyl) piperazine | 76851-55-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,4-bis(3-pyridylmethyl) piperazine
• 英文别名: N,N'-bis(3-pyridylmethyl)piperazine；1,4-bis(3-pyridylmethyl)piperazine；1,4-bis(3-pyridylmethy)piperazine；bis((3-pyridyl)methyl)piperazine；bis(3-pyridylmethyl)-piperazine；bis(3-pyridylmethyl)piperazine；1,4-Bis(pyridin-3-ylmethyl)piperazine
• CAS: 76851-55-3
• 化学式: C₁₆H₂₀N₄
• 分子量: 268.362
• InChiKey: XNBJJLRLOHVING-UHFFFAOYSA-N

物化性质

• 熔点：
  95 °C
• 沸点：
  198-201 °C(Press: 2 Torr)
• 密度：
  1.158±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  32.3
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4-bis(3-pyridylmethyl) piperazine 、 cobalt(II) thiocyanate 以 水 为溶剂， 以36%的产率得到[Co(NCS)2(N,N'-bis(3-pyridylmethyl)piperazine)2](n)
  参考文献：
  名称：

  Cobalt isothiocyanate coordination polymers constructed from isomeric bis(pyridylmethyl)piperazine ligands: Ribbon and chain motifs and a novel (3,4)-connected supramolecular layer

  摘要：

  Slow diffusion conditions have afforded a pair of cobalt isothiocyanate coordination polymers incorporating the. flexible and hydrogen-bonding capable organodiimines N,N'-bis(3-pyridylmethyl)piperazine (3-bpmp) and N,N'-bis(4-pyridylmethyl)piperazine (4-bpmp), which were characterized by single-crystal X-ray diffraction and spectral and elemental analysis. While both [Co(NCS)(2)(3-bpmp)(2)](n) (1) and {[Co(NCS)(2)(H2O)(2)(4-bpmp)] center dot 2H(2)O}(n) (2) possess one-dimensional (1-D) coordination polymer units, the donor disposition within the organodiimine promotes significant structural disparities. Compound 1 displays a 1-D double-chain motif, where each cobalt ion is bridged by two exobidentate 3-bpmp ligands. In contrast, compound 2 manifests a single chain pattern, with only one tethering 4-bpmp ligand joining adjacent cobalt ions. Extensive hydrogen-bonding patterns within the structure of 2 results in an intriguing supramolecular 2-D (3,4)-connected layer with (4.6(2))(2)(4(2).6(2).8(2)) topology. Thermal properties of these materials are also discussed. (C) 2008 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2008.07.032
• 作为产物：
  描述：

  3-氯甲基吡啶盐酸盐 、 1-[(3-吡啶)甲基]哌嗪 以71%的产率得到
  参考文献：
  名称：

  RONDAHL L., ACTA PHARM. SUEC., 1980, 17, NO 5, 292-294

  摘要：

  DOI：

文献信息

• Silver nitrate molecular species and coordination polymers with divergent supramolecular morphology constructed from hydrogen-bonding capable dipyridyl ligands
  作者：Gregory A. Farnum、Warren R. Knapp、Robert L. LaDuca

  DOI：10.1016/j.poly.2008.10.028

  日期：2009.2

  coordination polymers and one discrete cationic species with diverse silver coordination spheres. [Ag(NO3)(4,4′-dpk)]n (1, 4,4′-dpk = 4,4′-dipyridylketone), [Ag(4-bpmp)](NO3) · 6H2O} (2, 4-bpmp = bis(4-pyridylmethyl)piperazine) and [Ag2(NO3)(3-bpmp)(H2O)2]NO3}n (3, 3-bpmp = bis(3-pyridylmethyl)piperazine) all display 1-D coordination polymer chain or ribbon motifs. Long-range Ag⋯O interactions and/or hydrogen-bonding

  摘要硝酸银与各种具有氢键结合能力的二吡啶基配体发生固溶反应，生成了三种一维配位聚合物和一种具有多种银配位球的离散阳离子。[Ag（NO3）（4,4'-dpk）] n（1，4,4'-dpk = 4,4'-dipyridylketone），[Ag（4-bpmp）]（NO3）·6H2O}（2 ，4-bpmp =双（4-吡啶基甲基）哌嗪）和[Ag2（NO3）（3-bpmp）（H2O）2] NO3} n（3，3-bpmp =双（3-吡啶基甲基）哌嗪）全部显示一维配位聚合物链或丝带图案。远距离的Ag⋯O相互作用和/或氢键促进形成不同的超分子聚集体，例如1中的2-D双层平板，2中的三重互穿的3-D Diamondoid网络和2-D单层图3中的化合物2在其初始空隙中显示出“无限”的1-DT（5）2水分子带。[Ag（2，4'-pmpp）2]（NO3）·H2O}（4，2,4'-pmpp = 2-吡啶基（4
• Control of topology in luminescent nitrobenzene-detecting cadmium camphorate polymers via hydrogen-bonding capable dipyridyl ligands
  作者：Jack J. Przybyla、Robert L. LaDuca

  DOI：10.1016/j.ica.2018.03.041

  日期：2018.7

  Hydrothermal reaction of cadmium nitrate, d -camphoric acid (D-camH2), and a hydrogen-bonding capable dipyridyl ligand resulted in coordination polymers whose dimensionalities and topologies depend critically on the pyridyl nitrogen donor disposition and tether length. The four new phases were characterized by single crystal X-ray diffraction; racemization of the camphorate ligands was observed in three

  摘要硝酸镉，d-樟脑酸（D-camH2）和能与氢键结合的二吡啶基配体发生水热反应，形成了配位聚合物，其尺寸和拓扑结构主要取决于吡啶基氮供体的位置和系链长度。这四个新相的特征在于单晶X射线衍射。在三例中观察到了樟脑配体的消旋化。[Cd（dl-cam）（hdin）] n（1，hdin = N，N'-（己烷-1,6-二基）二异烟酰胺）显示2D锯齿（4,4）网格结构。[Cd2（d-cam）2（3-bpmp）（H2O）2] n（2，3-bpmp =双（3-吡啶基甲基）哌嗪）显示具有[Cd（d-cam）（ H2O）] n以3 bpmp梯级为支柱的立柱。次要乘积[Cd2（dl -cam）2（3-bpmp）] n（3）表现出基于Cd2O2}二聚体的6连接3D 41263 pcu拓扑。[Cd2（dl -cam）2（4-bpmp）] n（4，4-bpmp =双（4-吡啶甲基）哌嗪）也显示基于二聚体的6连接3D网络，但带有446108
• Luminescent cadmium 5-sulfoisophthalate dipyridylpiperazine coordination polymers with ladder, interpenetrated binodal net, or nanotube-embedded layer topologies
  作者：Brian L. Pickwick、Amy L. Pochodylo、Robert L. LaDuca

  DOI：10.1016/j.ica.2017.07.009

  日期：2017.9

  flexible dipyridyl ligands bis(3-pyridylmethyl)piperazine (3-bpmp), bis(4-pyridylmethyl)piperazine (4-bpmp) and bis(4-pyridylmethyl)homopiperazine (4-bpmh) have been utilized to prepare the cadmium 5-sulfoisophthalate (sip) coordination polymers [Cd2(sip)2(3-bpmpH2)(H2O)4]·19H2O}n (1), [Cd2(sip)2(4-bpmpH2)(4-bpmp)]·4H2O}n (2), and [Cd(sip)(4-bpmhH)]·11H2O}n (3). Compound 1 possesses 1D ladder motifs

  摘要利用构象柔性的二吡啶基配体双（3-吡啶基甲基）哌嗪（3-bpmp），双（4-吡啶基甲基）哌嗪（4-bpmp）和双（4-吡啶基甲基）高哌嗪（4-bpmh）制备了5-磺基间苯二甲酸镉（sip）配位聚合物[Cd2（sip）2（3-bpmpH2）（H2O）4]·19H2O} n（1），[Cd2（sip）2（4-bpmpH2）（4-bpmp ）]·4H2O} n（2）和[Cd（sip）（4-bpmhH）]·11H2O} n（3）。化合物1具有1D梯形基序，并带有由双质子化的3-bpmpH22 +梯级支撑的平行[Cd（sip）] nn-链。[Cd（sip）] nn-带束缚的sip磺酸盐基团的碳带同时存在于2和3中，但束缚配体的吡啶基臂的不同几何结构影响尺寸的变化。2条中的“线性” 4-bpmpH配体将[Cd（sip）] nn-条连接成3倍互穿的3条，具有（426）（426583）拓扑的5连接
• Control of dimensionality and topology in nickel and cobalt coordination polymers containing adamantane-based dicarboxylate and long-spanning dipyridyl ligands
  作者：Jamelah Z. Travis、Cassi J. LaRose、Robert L. LaDuca

  DOI：10.1016/j.ica.2016.10.043

  日期：2017.2

  4-bpfp = bis(4-pyridylformyl)piperazine) shows a simple stacked (4,4) layer structure. [Ni2(adc)2(3-bpmp)2(H2O)2]·15H2O}n (3, 3-bpmp = bis(3-pyridylmethyl)piperazine) also possesses stacked (4,4) grids, but with two different types of infinite water tapes in the interlamellar regions. [Ni2(adc)2(4-bpmp)2(H2O)2]·3H2O}n (4, 4-bpmp = bis(4-pyridylmethyl)piperazine) again exhibits (4,4) layers, but with two-fold

  摘要金属硝酸盐，金刚烷基二元羧酸和长跨度的二吡啶基配体的水热反应生成了六种配位聚合物，其结构通过单晶X射线衍射表征。[Ni2（adc）2（μ-H2O）（4-bpfh）2] n（1，adc = 1,3-金刚烷二羧酸酯，4-bpfh =双（4-吡啶基甲酰基）高哌嗪）显示基于[ Ni 2（OCO）2（μ-H2 O）]二聚体单元。[Ni（adc）（4-bpfp）2（H2O）2]·H2O} n（2，4-bpfp =双（4-吡啶基甲酰基）哌嗪）显示简单的堆叠（4,4）层结构。[Ni2（adc）2（3-bpmp）2（H2O）2]·15H2O} n（3，3-bpmp =双（3-吡啶基甲基）哌嗪）也具有堆叠的（4,4）网格，但具有两个层间区域中不同类型的无限水带。[Ni2（adc）2（4-bpmp）2（H2O）2]·3H2O} n（4，4-bpmp =双（4-吡啶基甲基）哌嗪）再次显示（4，4）层，但具有2D
• Ligand isomerism-controlled structural diversity of three new Cd(II) coordination polymers constructed by mixed dipyridyl-containing and benzenedicarboxylate ligands: syntheses, crystal structures, and photoluminescent properties
  作者：Xiuling Zhang、Yujing Wang

  DOI：10.1080/15533174.2016.1228669

  日期：2017.7.3

  Three new cadmium coordination polymers, [Cd(1,2-BDC)(L1)0.5(H2O)2]n(1), [Cd(1,2-BDC)(L2) (H2O)]n (2) and [Cd(1,3-BDC) (L2)0.5 (H2O)]·H2O}n (3), have been successfully synthesized by the assembly of Cd2+ ion, isomeric dipyridyl [L1 = 1,4-bis(4-pyridylmethyl) piperazine and L2 = 1,4-bis(3-pyridylmethyl) piperazine], and isomeric dicarboxylate ligands [1,2-H2BDC = 1.2-benzene dicarboxylic acid and 1

  三种新型镉配位聚合物，[Cd（1,2-BDC）（L 1）0.5（H 2 O）2 ] n（1），[Cd（1,2-BDC）（L 2）（H 2 O）通过组装Cd 2+离子已成功合成了] n（2）和[Cd（1,3-BDC）（L 2）0.5（H 2 O）]·H 2 O} n（3），异构二吡啶基[L 1 = 1,4-双（4-吡啶基甲基）哌嗪和L 2 = 1,4-双（3-吡啶基甲基）哌嗪]和异构二羧酸酯配体[1,2-H 2 BDC = 1.2-苯二羧酸和1,3-H2 BDC ＝ 1.3-苯-二羧酸]。配合物1和2均显示2D层结构。复合体3显示一维梯形结构。此外，在室温下以固态研究了配合物1-3的发光性质。