1-(N-phenylamino)-2-propanethiol | 90712-75-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-(N-phenylamino)-2-propanethiol
• 英文别名: 1-(N-phenylamino)propane-2-thiol；1-(phenylamino)propane-2-thiol；1-anilino-2-propanethiol；1-anilino-propane-2-thiol；1-Anilino-propan-2-thiol；2-Propanethiol, 1-(phenylamino)-；1-anilinopropane-2-thiol
• CAS: 90712-75-7
• 化学式: C₉H₁₃NS
• 分子量: 167.275
• InChiKey: JIJSMNXHYRRSAI-UHFFFAOYSA-N

物化性质

• 沸点：
  288.3±23.0 °C(Predicted)
• 密度：
  1.069±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  13
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(N-phenylamino)-2-propanethiol 、 sodium monochloroacetic acid 在 sodium hydroxide 作用下， 以 水 为溶剂， 反应 1.0h， 以55%的产率得到6-甲基-4-苯基硫代吗啉-3-酮
  参考文献：
  名称：

  New Synthesis of Tetrahydro-L,4-Thiazine-3-Ones from 1,2-Aminopropanethiols and α-Chlorocarboxylic Acids

  摘要：

  Tetrahydro-1,4-thiazine-3-ones 5 can be efficiently prepared by the condensation of 1,2-aminopropanethiols 1 and sodium chlorocarboxylates 4 under basic conditions.

  DOI：

  10.1080/00397919908085822
• 作为产物：
  描述：

  硫化丙烯 、 苯胺 反应 20.0h， 以53%的产率得到1-(N-phenylamino)-2-propanethiol
  参考文献：
  名称：

  Champseix, A.; Chanet, J.; Etienne, A., Bulletin de la Societe Chimique de France, 1985, # 3, p. 463 - 472

  摘要：

  DOI：

文献信息

• Monophyly, composition, and relationships within Saturniinae (Lepidoptera: Saturniidae): Evidence from two nuclear genes
  作者：Timothy P. Friedlander、Richard S. Peigler、Jerome C. Regier、Charles Mitter

  DOI：10.1163/187631202x00028

  日期：——

  The approximately 1500 species of Saturniidae or wild silk moths, which include some of the largest of all lepidopterans, have provided important model systems for studies of ecology, developmental genetics, and behavior. Such studies would benefit from a robust comparative framework, but there has been little phylogenetic analysis of this family. To address this, we use nuclear gene sequences to test hypotheses about the monophyly and internal relationships of the large and geographically widespread subfamily Saturniinae (63 genera, 644 spp.). Extending our previous examination of the genera of Attacini, we analyze coding sequence from elongation factor-1α (1240 nt) and dopa decarboxylase (typically 1051 nt) in 64 species representing four of five tribes in Saturniinae, 11 of 16 genera in Saturniini, and outgroups in Saturniidae and other bombycoids. The results support a recent postulate that Saturniinae, largely Oriental and Palearctic in distribution, should include the African Micragonini. The alternative that Micragonini or some subgroup thereof constitute its own subfamily (previously called Ludiinae) is shown to result in a paraphyletic Saturniinae. Micragonini group strongly with the tribe Bunaeini, also African. Monophyly for Saturniinae, including Micragonini, is strongly supported, as is a basal split between Attacini + Saturniini and Bunaeini + Micragonini. As a consequence, a postulated affinity to the African tribes of two Madagascan endemic Saturniini, thus rendering Saturniini paraphyletic, is rejected. However, there is no strong evidence either way on monophyly of Saturniini versus paraphyly with respect to the clearly monophyletic Attacini (atlas moths and relatives). This result reflects generally weak resolution of deeper divergences in Saturnini. Several lower-level groupings within Saturniini are strongly corroborated, including the tailed-hindwinged 'moon moths' (Argema, Actias, Graellsia) that specialize on resinous hostplants, and Saturnia sensu lato, a consolidation of eight small, former genera.

  摘要约有 1500 种鞘翅目或野生蚕蛾，其中包括一些体型最大的鳞翅目昆虫，为生态学、发育遗传学和行为学研究提供了重要的模式系统。这些研究将受益于一个强大的比较框架，但对该科的系统发育分析却很少。为了解决这个问题，我们利用核基因序列来检验大型且地理分布广泛的 Saturniinae 亚科（63 属，644 种）的单系和内部关系假设。我们扩展了之前对Attacini属的研究，分析了64个物种的伸长因子-1α（1240 nt）和多巴脱羧酶（通常为1051 nt）的编码序列，这些物种代表了Saturniinae亚科5个部落中的4个部落、Saturniini亚科16个属中的11个属，以及Saturniidae和其他bombbycoids的外群。这些结果支持了最近的一种推测，即主要分布于东方和古北区的 Saturniinae 应包括非洲的 Micragonini。另一种观点认为，Micragonini 或其某些亚群构成了自己的亚科（以前称为 Ludiinae），结果表明这将导致 Saturniinae 的旁系化。Micragonini与同属非洲的Bunaeini科有很强的同族关系。研究强烈支持 Saturniinae（包括 Micragonini）的单系性，以及 Attacini + Saturniini 和 Bunaeini + Micragonini 之间的基干分裂。因此，与马达加斯加特有的两个 Saturniini 非洲部落的亲缘关系，从而使 Saturniini 成为旁系的假设被否定。然而，对于 Saturniini 的单系性和与明显单系的 Attacini（地图册蛾及其近缘种）的旁系性，都没有强有力的证据。这一结果反映出对土星属中更深层次的分化的分辨率普遍较低。Saturniini 中几个较低层次的类群得到了强有力的证实，其中包括专食树脂寄主植物的有尾有翅 "月蛾"（Argema、Actias、Graellsia），以及由 8 个小型前属合并而成的广义 Saturnia。
• Farzaliev; Allakhverdiev; Rzaeva, Petroleum Chemistry, 1998, vol. 38, # 2, p. 126 - 131
  作者：Farzaliev、Allakhverdiev、Rzaeva

  DOI：——

  日期：——
• Reaction of amino thiols with chloroacetic acid and its esters
  作者：M. A. Allakhverdiev、V. M. Farzaliev、T. M. Khoiskaya、N. Yu. Ibragimov、E. M. Cherkasova

  DOI：10.1007/bf00515633

  日期：1984.3
• Tetrahydrothiazinones based on aminothiols and ?-chlorobutyric acid
  作者：M. A. Allakhverdiev、V. M. Farzaliev、T. M. Khoiskaya

  DOI：10.1007/bf00503594

  日期：1984.10
• ——
  作者：Kh. Kh. Nadim、A. T. Guseinova、A. M. Magerramov、M. A. Allakhverdiev

  DOI：10.1023/a:1020908910703

  日期：——

  Reactions of 1,2-aminopropanethiols with methyl trifluoropyruvate were studied, and the antibacterial and fungicidal activity of the resulting trifluoromethyl derivatives as additives to lubricants was examined.