Bis(3,8-dimethoxynaphthalen-2-yl)-phenylmethanol | 915706-53-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Bis(3,8-dimethoxynaphthalen-2-yl)-phenylmethanol
• 英文别名: bis(3,8-dimethoxynaphthalen-2-yl)-phenylmethanol
• CAS: 915706-53-5
• 化学式: C₃₁H₂₈O₅
• 分子量: 480.56
• InChiKey: HYZQPPQFHYOKOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  36
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Bis(3,8-dimethoxynaphthalen-2-yl)-phenylmethanol 在 三溴化硼 、 水 作用下， 以 二氯甲烷 为溶剂， 反应 0.33h， 以61%的产率得到C₂₈H₂₀O₄
  参考文献：
  名称：

  An Organic White Light-Emitting Fluorophore

  摘要：

  The synthesis of new benzo[a]- and [b] xanthene dye frameworks is described. A unique benzo[a] xanthene, seminaphtho[a] fluorone (SNAFR-1), is studied in a variety of media. The optimization of solution parameters and excitation wavelengths allows SNAFR-1 to display red, green, and blue emission bands of approximately equal intensities and also to produce white light. Ratiometric red (anion) and green (neutral) emissions are observed upon varying solution pH. A pH-independent violet-blue emission band is due to the addition of nucleophiles to the benzylic carbon of SNAFR-1.

  DOI：

  10.1021/ja0632207
• 作为产物：
  描述：

  苯甲酸甲酯 、 2,5-二甲氧基萘 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 以71%的产率得到Bis(3,8-dimethoxynaphthalen-2-yl)-phenylmethanol
  参考文献：
  名称：

  An Organic White Light-Emitting Fluorophore

  摘要：

  The synthesis of new benzo[a]- and [b] xanthene dye frameworks is described. A unique benzo[a] xanthene, seminaphtho[a] fluorone (SNAFR-1), is studied in a variety of media. The optimization of solution parameters and excitation wavelengths allows SNAFR-1 to display red, green, and blue emission bands of approximately equal intensities and also to produce white light. Ratiometric red (anion) and green (neutral) emissions are observed upon varying solution pH. A pH-independent violet-blue emission band is due to the addition of nucleophiles to the benzylic carbon of SNAFR-1.

  DOI：

  10.1021/ja0632207

文献信息

• WO2008/11508
  申请人：——

  公开号：——

  公开（公告）日：——
• Fluorescent Xanthenes and White Light Fluorophores
  申请人：Strongin Robert M.

  公开号：US20100051826A1

  公开（公告）日：2010-03-04

  Xanthene compounds are disclosed having fluorescence at multiple wavelengths. Also disclosed are methods for their synthesis and use. Some of the compounds fluoresce at three wavelengths, emitting white light. Uses include the imaging of biological tissues, illumination, and display technologies. Many of the compounds have large Stokes shifts, and are resistant to photobleaching. The fluorescence may be readily distinguished from that of endogenous fluorophores, and from that of most existing, commercially-available fluorescent probes. The compounds are well suited for use in “multiplexing” techniques. They exhibit clear isosbestic and isoemissive points, and have broad absorption and emission ranges.
• US8350064B2
  申请人：——

  公开号：US8350064B2

  公开（公告）日：2013-01-08
• An Organic White Light-Emitting Fluorophore
  作者：Youjun Yang、Mark Lowry、Corin M. Schowalter、Sayo O. Fakayode、Jorge O. Escobedo、Xiangyang Xu、Huating Zhang、Timothy J. Jensen、Frank R. Fronczek、Isiah M. Warner、Robert M. Strongin

  DOI：10.1021/ja0632207

  日期：2006.11.1

  The synthesis of new benzo[a]- and [b] xanthene dye frameworks is described. A unique benzo[a] xanthene, seminaphtho[a] fluorone (SNAFR-1), is studied in a variety of media. The optimization of solution parameters and excitation wavelengths allows SNAFR-1 to display red, green, and blue emission bands of approximately equal intensities and also to produce white light. Ratiometric red (anion) and green (neutral) emissions are observed upon varying solution pH. A pH-independent violet-blue emission band is due to the addition of nucleophiles to the benzylic carbon of SNAFR-1.