2,3-diethylbenzo[b]thiophene | 54789-20-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 2,3-diethylbenzo[b]thiophene
• 英文别名: 2,3-diethyl-benzo[b]thiophene；2,3-Diaethyl-benzothiophen；2,3-Diaethyl-thionaphthen；Benzo[b]thiophene, 2,3-diethyl-；2,3-diethyl-1-benzothiophene
• CAS: 54789-20-7
• 化学式: C₁₂H₁₄S
• 分子量: 190.309
• InChiKey: HJLFFOFIJTWBAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  28.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-ethyl-2-(phenylthio)butanal 在 triethyloxonium fluoroborate 作用下， 以 二氯甲烷 为溶剂， 以88%的产率得到2,3-diethylbenzo[b]thiophene
  参考文献：
  名称：

  Groot, Aede de; Jansen, Ben J. M., Synthesis, 1985, # 4, p. 434 - 436

  摘要：

  DOI：

文献信息

• Cu-Catalyzed Synthesis of Diaryl Thioethers and <i>S</i>-Cycles by Reaction of Aryl Iodides with Carbon Disulfide in the Presence of DBU
  作者：Peng Zhao、Hang Yin、Hongxin Gao、Chanjuan Xi

  DOI：10.1021/jo400709s

  日期：2013.5.17

  Diaryl thioethers and S-cycles were obtained on the basis of the copper-catalyzed reaction of carbon disulfide and aryl iodides in the presence of DBU. This reaction enables the one-pot synthesis of diaryl thioethers by employing cheap, available, and easy-to-handle carbon disulfide with aryl iodides. The reaction was successfully employed in the construction of sulfur-containing cyclic molecules.

  在DBU存在下，基于二硫化碳和芳基碘化物的铜催化反应，获得了二芳基硫醚和S-环。通过使用廉价，易得且易于处理的二硫化碳与芳基碘化物，该反应能够一锅合成二芳基硫醚。该反应成功地用于构建含硫的环状分子。
• Benati, Luisa; Montevecchi, Pier Carlo; Spagnolo, Piero, Journal of the Chemical Society. Perkin transactions I, 1992, # 13, p. 1659 - 1664
  作者：Benati, Luisa、Montevecchi, Pier Carlo、Spagnolo, Piero

  DOI：——

  日期：——
• Benati, Luisa; Montevecchi, Pier Carlo; Spagnolo, Piero, Journal of the Chemical Society. Perkin transactions I, 1991, # 9, p. 2103 - 2109
  作者：Benati, Luisa、Montevecchi, Pier Carlo、Spagnolo, Piero

  DOI：——

  日期：——
• Cu-Catalyzed Double S-Alkenylation of Potassium Sulfide: A Highly Efficient Method for the Synthesis of Various Thiophenes
  作者：Wei You、Xiaoyu Yan、Qian Liao、Chanjuan Xi

  DOI：10.1021/ol101619s

  日期：2010.9.3

  An efficient synthetic approach to variously substituted thiophenes has been developed through copper-catalyzed tandem S-alkenylation of potassium sulfide with 1,4-dilodo-1,3-dienes.
• An efficient one-pot method for the preparation of polysubstituted benzothiophenes
  作者：Stephen L. Buchwald、Qun Fang

  DOI：10.1021/jo00273a006

  日期：1989.6