5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-[(E)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-sulfonatophenyl]ethenyl]benzenesulfonate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-[(E)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-sulfonatophenyl]ethenyl]benzenesulfonate
• 化学式: C40H44N12O10S2
• 分子量: 917.0
• InChiKey: CNGYZEMWVAWWOB-VAWYXSNFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  64
• 可旋转键数：
  22
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  338
• 氢给体数：
  10
• 氢受体数：
  22

反应信息

• 作为产物：
  描述：

  、 ammonium hydroxide 、 、 、 、 钠 、 硫酸 、 、 disodium;2-N-[4-[(E)-2-[4-[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-2-sulfonatophenyl]ethenyl]-3-sulfonatophenyl]-6-morpholin-4-yl-4-N-phenyl-1,3,5-triazine-2,4-diamine 、 、 甲烷 、 水 反应 4.75h， 以a solution of Calcofluor M2R (3.30 g) in water, and water to obtain a slurry的产率得到5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-[(E)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-1-ium-2-yl]amino]-2-sulfonatophenyl]ethenyl]benzenesulfonate
  参考文献：
  名称：

  COATED PESTICIDAL MATRICES, A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

  摘要：

  本发明提供了改进的涂层杀虫剂基质及其制备方法。本发明还提供了一种含有改进的涂层杀虫剂基质的可湿性粉剂杀虫剂组合物。

  公开号：

  US20030194419A1

文献信息

• STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE
  申请人：SurModics, Inc.

  公开号：US20140162083A1

  公开（公告）日：2014-06-12

  The invention is directed to latent reactive and polymerizable derivatives of fluorescent stilbene-based compounds. The compounds can be used to provide articles with a fluorescence property, such as medical devices (e.g., catheters). The fluorescent compounds can be used in association with polymers, or can be incorporated into polymers, and the polymers used in a coating composition on the article surface. The compounds allow for visual or machine inspection of coating properties such as uniformity of coverage.

  这项发明涉及荧光基苯乙烯化合物的潜在反应性和聚合物化衍生物。这些化合物可用于赋予物品荧光特性，例如医疗器械（如导管）。荧光化合物可与聚合物结合使用，或者可以被纳入聚合物中，并且聚合物可用作涂层组合物涂覆在物品表面。这些化合物允许对涂层性能进行目视或机器检查，比如涂层覆盖的均匀性。
• Composition comprising at least one conductive polymer and at least one fluorescent dye and/or at least one optical brightener, and process for use thereof
  申请人：Rollat-Corvol Isabelle

  公开号：US20050048023A1

  公开（公告）日：2005-03-03

  The present disclosure relates to a composition comprising, in a cosmetically acceptable medium, at least one fluorescent dye and/or an optical brightener, and at least one conductive polymer. The present disclosure also relates to a process for treating keratin fibers, for instance human keratin fibers, such as the hair using such a composition to give keratin fibers an optical effect.

  本公开涉及一种组合物，包括至少一种荧光染料和/或一种光学增白剂，并且至少一种导电聚合物，均存在于化妆品可接受的介质中。本公开还涉及一种处理角蛋白纤维（例如人类角蛋白纤维，如头发）的方法，使用这种组合物为角蛋白纤维提供光学效果。
• [EN] HAIR CONDITIONING COMPOSITION COMPRISING CARBOXYLIC ACID/CARBOXYLATE COPOLYMER, SILICONE COMPOUND, AND HIGH MELTING POINT COMPOUND<br/>[FR] COMPOSITION POUR LE CONDITIONNEMENT DES CHEVEUX COMPRENANT UN COPOLYMERE ACIDE CARBOXYLIQUE/CARBOXYLATE, UN COMPOSE DE SILICONE ET UN COMPOSE AYANT UN POINT DE FUSION ELEVE
  申请人：PROCTER & GAMBLE

  公开号：WO2000006098A1

  公开（公告）日：2000-02-10

  Disclosed is a hair conditioning composition comprising: (1) a carboxylic acid/carboxylate copolymer; (2) a silicone compound; (3) a high melting point compound; and (4) an aqueous carrier.

  公开的一种头发护理组合物包括：（1）羧酸/羧酸盐共聚物；（2）硅氧烷化合物；（3）高熔点化合物；和（4）水性载体。
• COATED PESTICIDAL MATRICES, A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
  申请人：——

  公开号：US20030194419A1

  公开（公告）日：2003-10-16

  The present invention provides improved coated pesticidal matrices and a process for their preparation. The present invention also provides a wettable powder pesticidal composition containing the improved coated pesticidal matrices.

  本发明提供了改进的涂层杀虫剂基质及其制备方法。本发明还提供了一种含有改进的涂层杀虫剂基质的可湿性粉剂杀虫剂组合物。
• Phosphate transport inhibitors
  申请人：Jozefiak H. Thomas

  公开号：US20070021509A1

  公开（公告）日：2007-01-25

  Disclosed are compounds which have been identified as inhibitors of phosphate transport. Many of the compounds are represented by Structural Formula (I): Ar 1 —W—X—Y—Ar 2 ; or a pharmaceutically acceptable salt thereof. Ar 1 and Ar 2 are independently a substituted or unsubstituted aryl group or an optionally substituted five membered or six membered non-aromatic heterocylic group fused to an optionally substituted monocylic aryl group. W and Y are independently a covalent bond or a C1-C3 substituted or unsubstituted alkylene group. X is a heteroatom-containing functional group, an aromatic heterocyclic group, substituted aromatic heterocyclic group, non-aromatic heterocyclic group, substituted non-aromatic heterocyclic group, an olefin group or a substituted olefin group. Also disclosed are methods of treating a subject with a disease associated with hyperphosphatemia, as well as a disease mediated by phosphate-transport function. The methods comprise the step of administering an effective amount of the one of the compounds described above.

  本发明涉及已被鉴定为磷酸盐转运抑制剂的化合物。其中许多化合物由结构式（I）表示：Ar1-W-X-Y-Ar2；或其药学上可接受的盐。其中，Ar1和Ar2独立地为取代或未取代的芳基团或可选取代的五元或六元非芳基杂环团与可选取代的单环芳基团融合。W和Y独立地为共价键或C1-C3取代或未取代的烷基链。X为含杂原子的官能团、芳基杂环团、取代的芳基杂环团、非芳基杂环团、取代的非芳基杂环团、烯烃基或取代的烯烃基。本发明还涉及治疗与高磷血症相关的疾病以及由磷酸盐转运功能介导的疾病的方法。该方法包括给予上述化合物之一的有效量。