exo-5-aminomethyl-endo-5-methylbicyclo<2.2.1>hept-2-ene | 173309-01-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: exo-5-aminomethyl-endo-5-methylbicyclo<2.2.1>hept-2-ene
• 英文别名: exo-5-aminomethyl-endo-5-methylbicyclo[2.2.1]hept-2-ene；(2-methylbicyclo[2.2.1]hept-5-en-2-yl)methylamine；Bicyclo[2.2.1]hept-2-ene-2-methanamine, 2-methyl-, (1R,2S,4R)-rel-；[(1S,2R,4S)-2-methyl-2-bicyclo[2.2.1]hept-5-enyl]methanamine
• CAS: 173309-01-8
• 化学式: C₉H₁₅N
• 分子量: 137.225
• InChiKey: SAFZYLFJZOUNMP-YIZRAAEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-萘异硫氰酸酯 、 exo-5-aminomethyl-endo-5-methylbicyclo<2.2.1>hept-2-ene 以 苯 为溶剂， 以76%的产率得到1-[[(1S,2R,4S)-2-methyl-2-bicyclo[2.2.1]hept-5-enyl]methyl]-3-naphthalen-1-ylthiourea
  参考文献：
  名称：

  Kas'yan, A. O.; Krasnovskaya, O. Yu.; Okovityi, S. I., Russian Journal of Organic Chemistry, 1995, vol. 31, # 3, p. 311 - 319

  摘要：

  DOI：
• 作为产物：
  描述：

  endo-5-methylbicyclo<2.2.1>hept-2-ene-exo-5-carbonitrile 在 lithium aluminium tetrahydride 作用下， 以73%的产率得到exo-5-aminomethyl-endo-5-methylbicyclo<2.2.1>hept-2-ene
  参考文献：
  名称：

  Kas'yan, A. O.; Krasnovskaya, O. Yu.; Okovityi, S. I., Russian Journal of Organic Chemistry, 1995, vol. 31, # 3, p. 311 - 319

  摘要：

  DOI：

文献信息

• An efficient recyclable peroxometalate-based polymer-immobilised ionic liquid phase (PIILP) catalyst for hydrogen peroxide-mediated oxidation
  作者：Simon Doherty、Julian G. Knight、Jack R. Ellison、David Weekes、Ross W. Harrington、Christopher Hardacre、Haresh Manyar

  DOI：10.1039/c2gc16679h

  日期：——

  metathesis polymerisation (ROMP) of a pyrrolidinium-functionalised norbornene-based monomer with cyclooctene. The derived peroxophosphotungstate-based polymer-immobilised ionic liquid phase (PIILP) catalyst is an efficient and recyclable system for the epoxidation of allylic alcohols and alkenes, with only a minor reduction in performance on successive cycles.

  线性 阳离子具有可调节的表面性能和微观结构的装饰聚合物载体已通过 开环易位聚合 （欢蹦乱跳）的吡咯烷鎓官能化的降冰片烯基单体与 环辛烯。派生的过氧磷钨酸盐聚合物-固定 离子液体 阶段（PIILP） 催化剂 是烯丙基环氧化反应的有效和可回收系统 酒类 和 烯烃，而连续周期的性能只会略有下降。
• ——
  作者：A. O. Kas'yan、E. T. Zlenko、S. I. Okovityi、E. A. Golodaeva、L. I. Kas'yan

  DOI：10.1023/a:1013852002440

  日期：——

  exo-5-Aminomethyl-endo-5-methylbicyclo[2.2.1]hept-2-ene and its 2,3-epoxy derivative were synthesized, and their geometric parameters and conformational properties, in particular the barriers to rotation of the aminomethyl fragment about the exocyclic CS-C bond, were studied by the molecular-mechanics method (MMX) and compared with those found for structurally related exo-5-aminomethylbicyclo[2.2.1]hept-2-ene. The title compounds were brought into reactions with electrophilic reagents: arenesulfonyl chlorides, isocyanates, and isothiocyanates.