triallylmethylamine | 50456-50-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: triallylmethylamine
• 英文别名: 1,1-diallyl-but-3-enylamine；4-Amino-4-allyl-heptadien-(1.6)；1,1-Diallyl-but-3-enylamin；Triallylmethyl-amin；1,1-di-(2-propen-1-yl)-3-buten-1-ylamine；4-allyl-4-amino-1,6-heptadiene；4-prop-2-enylhepta-1,6-dien-4-amine
• CAS: 50456-50-3
• 化学式: C₁₀H₁₇N
• 分子量: 151.252
• InChiKey: SLSPAFKWEBMSDT-UHFFFAOYSA-N

物化性质

• 沸点：
  80 °C(Press: 20 Torr)
• 密度：
  0.828±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  triallylmethylamine 在 乙醇 、 铂 作用下， 生成 二丙丁胺
  参考文献：
  名称：

  Henze; Allen; Leslie, Journal of the American Chemical Society, 1943, vol. 65, p. 88

  摘要：

  DOI：
• 作为产物：
  描述：

  4-methyl-N-(4-prop-2-enylhepta-1,6-dien-4-yl)benzenesulfonamide 在 sodium 作用下， 以 氨 为溶剂， 生成 triallylmethylamine
  参考文献：
  名称：

  N-tosyl iminoethers et iminocarbonates d'alkyle : Synthons d'amines primaires a structure ramifiee

  摘要：

  DOI：

  10.1016/s0040-4039(00)95154-2

文献信息

• Secondary amines
  申请人：Labaz

  公开号：US04201725A1

  公开（公告）日：1980-05-06

  Methylamine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.3 each represent a hydrogen atom or a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 6 carbon atoms, R.sub.2 represents a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 2 to 7 carbon atoms with the proviso that when R.sub.2 represents an alkenyl radical of the formula CH.dbd.CH--R.sub.6 or an alkynyl radical of the formula C.tbd.C--R.sub.6, in which R.sub.6 represents a hydrogen atom or a straight- or branched-chain alkyl radical of 1 to 5 carbon atoms, R.sub.1 and R.sub.3 each represent an atom of hydrogen or an alkyl radical, R.sub.4 and R.sub.5, which are the same or different, each respresent a hydrogen atom, a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 5 carbon atoms or an .omega.-hydroxyalkyl radical containing from 2 to 5 carbon atoms or R.sub.4 and R.sub.5, when they are taken together represent an alkylene radical containing from 2 to 6 carbon atoms, an alkylidene radical containing from 1 to 5 carbon atoms or the radical --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --CH.sub.2 --, R.sub.1, R.sub.2 and R.sub.3 being such that the trisubstituted methylamine radical possesses no more than 13 carbon atoms. They are useful for treating Parkinson's disease and for correcting extra-pyramidal disturbances provoked by neuroleptics.

  甲基胺衍生物的公式为：##STR1##以及药学上可接受的酸加成盐，其中R.sub.1和R.sub.3各自代表一个氢原子或一个含有1至6个碳原子的直链或支链烷基、烯基或炔基自由基，R.sub.2代表一个含有2至7个碳原子的直链或支链烷基、烯基或炔基自由基，条件是当R.sub.2代表一个公式为CH.dbd.CH--R.sub.6的烯基自由基或一个公式为C.tbd.C--R.sub.6的炔基自由基时，其中R.sub.6代表一个氢原子或一个含有1至5个碳原子的直链或支链烷基自由基，R.sub.1和R.sub.3各自代表一个氢原子或一个烷基自由基，R.sub.4和R.sub.5相同或不同，各自代表一个氢原子，一个含有1至5个碳原子的直链或支链烷基、烯基或炔基自由基，或一个含有2至5个碳原子的ω-羟基烷基自由基，或者R.sub.4和R.sub.5共同代表一个含有2至6个碳原子的亚烷基自由基，一个含有1至5个碳原子的亚烷基自由基或自由基--CH.sub.2 --CH.sub.2 --O--CH.sub.2 --CH.sub.2 --，R.sub.1、R.sub.2和R.sub.3使得三取代甲基胺自由基最多含有13个碳原子。它们可用于治疗帕金森病，并用于纠正由神经阻滞剂引起的锥体外系扰动。
• Active derivatives of methylamine in therapeutic compositions and
  申请人：Labaz

  公开号：US04057644A1

  公开（公告）日：1977-11-08

  Methylamine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.3 each represent a hydrogen atom or a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 6 carbon atoms, R.sub.2 represents a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 2 to 7 carbon atoms with the proviso that when R.sub.2 represents an alkenyl radical of the formula CH.dbd.CH--R.sub.6 or an alkynyl radical of the formula C.tbd.C--R.sub.6, in which R.sub.6 represents a hydrogen atom or a straight- or branched-chain alkyl radical of 1 to 5 carbon atoms, R.sub.1 and R.sub.3 each represent an atom of hydrogen or an alkyl radical, R.sub.4 and R.sub.5, which are the same or different, each represent a hydrogen atom, a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 5 carbon atoms or an .omega.-hydroxyalkyl radical containing from 2 to 5 carbon atoms or R.sub.4 and R.sub.5, when they are taken together represent an alkylene radical containing from 2 to 6 carbon atoms, an alkylidene radical containing from 1 to 5 carbon atoms or the radical --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --CH.sub.2 --, R.sub.1, R.sub.2 and R.sub.3 being such that the trisubstituted methylamine radical possesses no more than 13 carbon atoms. They are useful for treating Parkinson's disease and for correcting extra-pyramidal disturbances provoked by neuroleptics.

  Methylamine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.3 each represent a hydrogen atom or a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 6 carbon atoms, R.sub.2 represents a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 2 to 7 carbon atoms with the proviso that when R.sub.2 represents an alkenyl radical of the formula CH.dbd.CH--R.sub.6 or an alkynyl radical of the formula C.tbd.C--R.sub.6, in which R.sub.6 represents a hydrogen atom or a straight- or branched-chain alkyl radical of 1 to 5 carbon atoms, R.sub.1 and R.sub.3 each represent an atom of hydrogen or an alkyl radical, R.sub.4 and R.sub.5, which are the same or different, each represent a hydrogen atom, a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 5 carbon atoms or an .omega.-hydroxyalkyl radical containing from 2 to 5 carbon atoms or R.sub.4 and R.sub.5, when they are taken together represent an alkylene radical containing from 2 to 6 carbon atoms, an alkylidene radical containing from 1 to 5 carbon atoms or the radical --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --CH.sub.2 --, R.sub.1, R.sub.2 and R.sub.3 being such that the trisubstituted methylamine radical possesses no more than 13 carbon atoms. They are useful for treating Parkinson's disease and for correcting extra-pyramidal disturbances provoked by neuroleptics.
• Hair treatment compositions and hair after-treatment compositions for protection against damage by chemical treatment and for the repair of already damaged hair comprising as active substances alkylguanidine compounds
  申请人：GOLDSCHMIDT AG

  公开号：US20040258652A1

  公开（公告）日：2004-12-23

  Hair treatment compositions and hair after-treatment compositions are provided for the prevention of damage by chemical treatment compositions and for the repair of already damaged hair, wherein, as active substances, at least one of the compounds of the general formulae (I) and/or (II) are additionally used. 1

  提供了用于预防化学处理造成的损害以及修复已经受损头发的头发处理组合物和后处理组合物，其中作为活性物质，至少使用了一种通式（I）和/或（II）的化合物。
• Use of alkylguanidine compounds for the treatment and after-treatment of hair
  申请人：GOLDSCHMIDT AG

  公开号：US20040258651A1

  公开（公告）日：2004-12-23

  Hair treatment compositions and hair treatment compositions are provided for improving the combability, handle, disentanglability, volume and luster, which comprises additionally using, as active substances, at least one of the compounds of the general formulae (I) and/or (II). 1

  提供用于改善梳理性能、手感、易梳性、蓬松度和光泽度的头发护理组合物和头发护理组合物，其中还包括使用至少一种通式（I）和/或（II）化合物作为活性物质。
• [EN] CARBONYLATION CATALYST AND PROCESS<br/>[FR] CATALYSEUR DE CARBONYLATION ET PROCÉDÉ ASSOCIÉ
  申请人：BP CHEM INT LTD

  公开号：WO2014135661A1

  公开（公告）日：2014-09-12

  A catalyst and process for the production of methyl acetate by contacting dimethyl ether and carbon monoxide in the presence of a catalyst which is a zeolite of micropore volume of 0.01 ml/g or less.

  一种催化剂和生产甲酸甲酯的方法，通过在存在孔体积为0.01毫升/克或更少的沸石催化剂的情况下，使二甲醚和一氧化碳接触。