Peg(2000)-dspe

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: Peg(2000)-dspe
• 英文别名: [(2R)-3-[hydroxy-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxycarbonylamino]ethoxy]phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
• 化学式: C₁₃₃H₂₆₄NO₅₅P
• 分子量: 2788.5
• InChiKey: ZTKRPKUFADROTE-PQXSQUMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  190
• 可旋转键数：
  180
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  562
• 氢给体数：
  2
• 氢受体数：
  55

文献信息

• Biocompatible Nanoparticles with Aggregation Induced Emission Characteristics as Fluorescent Bioprobes and Methods of Using the Same for In Vitro and In Vivo Imaging
  申请人：Tang Benzhong

  公开号：US20140328764A1

  公开（公告）日：2014-11-06

  The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.

  有机荧光化合物构成的发光生物探针的发展，其具有聚集诱导发射（AIE）特性，生产方法以及它们在体外和体内生物成像方面的实际应用。
• Liposome Compositions and Methods of Use Thereof
  申请人：Reshetnyak Yana K.

  公开号：US20120039990A1

  公开（公告）日：2012-02-16

  The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.
• USE OF VEGFR1 AS A BIOMARKER
  申请人：SILENCE THERAPEUTICS AG

  公开号：US20140179755A1

  公开（公告）日：2014-06-26

  The present invention is related to the use of VEGFR1 or of a nucleic acid coding for VEGFR1 as a biomarker in a method for the treatment of a subject, wherein the method for the treatment comprises administering to the subject a PKN3 inhibitor.
• Liposome Structures And Methods of Use Thereof
  申请人：Rhode Island Board of Governors for Higher Educati

  公开号：US20150086617A1

  公开（公告）日：2015-03-26

  The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.
• BIS-POLYMER LIPID-PEPTIDE CONJUGATES AND NANOPARTICLES THEREOF
  申请人：The Regents of the University of California

  公开号：US20170049901A1

  公开（公告）日：2017-02-23

  The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed.