N.N-Dimethyl-3-cyclohexyl-propylamin | 67810-12-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N.N-Dimethyl-3-cyclohexyl-propylamin
• 英文别名: (3-cyclohexyl-propyl)-dimethyl-amine；3-Dimethylamino-1-cyclohexyl-propan；3-cyclohexyl-N,N-dimethylpropylamine；3-cyclohexyl-N,N-dimethylpropan-1-amine
• CAS: 67810-12-2
• 化学式: C₁₁H₂₃N
• 分子量: 169.31
• InChiKey: BOICYHUUQXCIME-UHFFFAOYSA-N

物化性质

• 沸点：
  212-214 °C(Press: 708 Torr)
• 密度：
  0.843±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N,N-二甲基-3-苯基丙烷-1-胺 在 高氯酸 、 钯 、 溶剂黄146 作用下， 生成 N.N-Dimethyl-3-cyclohexyl-propylamin
  参考文献：
  名称：

  Kindler; Hedemann; Schaerfe, Justus Liebigs Annalen der Chemie, 1948, vol. 560, p. 215,219

  摘要：

  DOI：

文献信息

• Methylformate as replacement of syngas in one-pot catalytic synthesis of amines from olefins
  作者：Eduard Karakhanov、Anton Maksimov、Yulia Kardasheva、Elena Runova、Roman Zakharov、Maria Terenina、Corey Kenneally、Victor Arredondo

  DOI：10.1039/c3cy00862b

  日期：——

  general approach for the one-pot hydroaminomethylation of olefins using methylformate as formylating agent instead of synthesis gas (syngas) has been proposed. Herein we report that a Ru–Rh catalytic system demonstrates high activity in a tandem conversion of a series of n-alkenes into amines using methylformate with yields 58–92% (6 h). The selectivity for the normal amine reached 96% with catalysis by

  已经提出了一种新的通用方法，该方法使用甲酸酯甲酯作为甲酰化剂代替合成气（合成气）进行一锅法烯烃的氢氨基甲基化。本文中，我们报道Ru-Rh催化体系在使用甲酸甲酯的一系列正构烯烃串联转化为胺中表现出高活性，产率为58-92％（6小时）。在Ru羰基络合物Ru 3（CO）12的催化下，对正胺的选择性达到96％，在这种情况下，相对于胺，总产率为55％。在Ru催化体系中添加Rh络合物，可显着提高末端和内部烯烃的氢氨甲基化率，并将胺的收率提高至82-93％（6-12小时）。
• Compounds
  申请人：SMITH KLINE & FRENCH LABORATORIES LIMITED

  公开号：EP0385686A2

  公开（公告）日：1990-09-05

  Polystyrene polymers of structure : in which, R' and R2 are the same or different and are each C1-4 alkyl; R3 is (CH2)nR4 in which R4 is C3-6 cycloalkyl or a bicyclic carbocyclic ring of up to 10 carbon atoms and n is 1 to 12, or R3 is (CH2)nCH = RSR6 in which n is 1 to 12 and R5 and R6 together form a C3-6 cycloalkyl ring or a bicyclic carbocyclic ring of up to 10 carbon atoms; R7 is hydrogen or a group CH2NR1R2R3X-; X- is a counter ion; a, b and c are numbers which indicate the relative molar percentages of the units present in said polymer, (b) being from about 1 to about 10 molar percent, and (c) being from about 30 to about 98 molar percent; m is a number indicating the degree of polymerisation of said polymer, processes for their preparation, compositions containing them and their use in therapy as bile acid sequestering agents.

  结构如下的聚苯乙烯聚合物 其中，R'和 R2 相同或不同，均为 C1-4 烷基；R3为(CH2)nR4，其中R4为C3-6环烷基或碳原子数不超过10的双环碳环，n为1至12，或R3为(CH2)nCH＝RSR6，其中n为1至12，R5和R6共同形成C3-6环烷基环或碳原子数不超过10的双环碳环；R7为氢或基团CH2NR1R2R3X-；X-为反离子；a、b 和 c 是数字，表示存在于所述聚合物中的单元的相对摩尔百分比，(b) 约为 1 至约 10 摩尔百分比，(c) 约为 30 至约 98 摩尔百分比；m 是数字，表示所述聚合物的聚合度、其制备工艺、含有它们的组合物以及它们在治疗中作为胆汁酸螯合剂的用途。
• COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS
  申请人：Infinity Discovery, Inc.

  公开号：EP1768966B1

  公开（公告）日：2012-03-07
• PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF
  申请人：W. R. Grace & Co.-Conn

  公开号：EP2663400A1

  公开（公告）日：2013-11-20
• [EN] PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN CATALYSEUR MÉTALLOCÈNE MODIFIÉ, CATALYSEUR AINSI PRODUIT ET SON UTILISATION
  申请人：GRACE W R & CO

  公开号：WO2012097146A1

  公开（公告）日：2012-07-19

  Olefin polymerization catalysts or catalyst systems comprising a mixture, contact product, reaction product or complex comprising as elements or components: (A) at least one metallocene pre-catalyst compound or polymerization active metallocene compound; (B) at least one titanium containing metallocene compound; and when (A) is a metallocene pre- catalyst compound, (C) at least one activator; provided however: (I) the titanium-containing metallocene compound is inactive or substantially inactive for the polymerization of olefins prior to or concurrently with the use of the catalyst system for olefin polymerization. Also disclosed are processes for producing the catalyst system and polyolefins having desirable combinations of properties, including melt index and molecular weight distribution, which properties are particularly desirable for the manufacture of polyolefin film products, especially LLDPE film. A preferred catalyst comprises a zirconium or hafnium metal containing metallocene, an inactivated titanocene and a SiO2 support carrier.