2,8-Dioctyl phenothiazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 2,8-Dioctyl phenothiazine
• 英文别名: 2,8-dioctyl-10H-phenothiazine
• 化学式: C₂₈H₄₁NS
• 分子量: 423.7
• InChiKey: QYZRFLASALOUKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.7
• 重原子数：
  30
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PRODUCTION OF TERT-BUTYL ESTERS OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS
  申请人：BASF SE

  公开号：US20190002389A1

  公开（公告）日：2019-01-03

  A process for continuously preparing the tert-butyl ester of an ethylenically unsaturated carboxylic acid, by a) reacting an ethylenically unsaturated carboxylic acid with isobutene in the presence of an acidic catalyst to give an esterification mixture; b) removing the acidic catalyst; c) removing low-boiling components; and d) supplying a tert-butyl ester-comprising liquid to a distillation apparatus and subjecting it to purifying distillation in the distillation apparatus, where d 1 ) in the distillation apparatus the tert-butyl ester-comprising liquid is separated into a tert-butyl ester-comprising gaseous top product and a carboxylic acid-comprising liquid bottom product; d 2 ) the tert-butyl ester-comprising gaseous top product is at least partly condensed and the condensate is recycled partly as reflux to the distillation apparatus; d 3 ) the carboxylic acid-comprising liquid bottom product is recycled at least partly to step a); d 4 ) carboxylic acid-comprising liquid bottom product is drawn off and passed to a heater; a superheated, liquid recycle stream is taken from the heater; and the superheated recycle stream is let down into the distillatiuon apparatus; and d 5 ) at least in the top region of the distillation apparatus, the distillation apparatus walls in contact with the vapor, at least in sub-regions, are heated and/or thermally insulated. In the course of the process, the separation of the tert-butyl ester from unreacted carboxylic acid is carried on with a particularly low level of accompanying polymerization both of the tert-butyl ester and of the carboxylic acid.

  一种连续制备乙烯基不饱和羧酸叔丁酯的方法，包括以下步骤：a）在酸性催化剂存在下，将乙烯基不饱和羧酸与异丁烯反应，得到酯化混合物；b）去除酸性催化剂；c）去除低沸点成分；d）将含有叔丁酯的液体供给蒸馏设备，在蒸馏设备中进行纯化蒸馏，其中d1）在蒸馏设备中，将含有叔丁酯的液体分离成含有叔丁酯的气态顶部产品和含有羧酸的液态底部产品；d2）将含有叔丁酯的气态顶部产品至少部分冷凝，所得冷凝物部分作为回流物回收至蒸馏设备；d3）将含有羧酸的液态底部产品至少部分回收至步骤a）；d4）将含有羧酸的液态底部产品抽出并通过加热器，从加热器中取出过热的液态回收流，将过热的回收流放入蒸馏设备中；d5）至少在蒸馏设备的顶部区域，与蒸汽接触的蒸馏设备壁面至少在子区域中加热和/或热绝缘。在该过程中，从未反应的羧酸中分离出叔丁酯，伴随的叔丁酯和羧酸的聚合水平特别低。
• Polymerization inhibitor composition for vinyl aromatic compounds
  申请人：UNIROYAL CHEMICAL COMPANY, Inc.

  公开号：EP0325059A2

  公开（公告）日：1989-07-26

  Vinyl aromatic compounds are stabilized against polymerization by the addition of an effective amount of a polymerization inhibition composition comprising (a) a phenothiazine compound; and (b) an aryl-substituted phenylenediamine compound. In other aspects, this invention is directed to a vinyl aromatic composition stabilized against polymerization by such polymerication inhibitor composition, as well as to a method of stabilizing a vinyl aromatic composition against polymerization which method comprises adding an effective amount of such polymerization inhibitor composition.

  通过添加有效量的聚合抑制剂组合物来稳定乙烯基芳香族化合物以防止聚合，该组合物包括(a)吩噻嗪化合物；和(b)芳基取代的苯二胺化合物。在其他方面，本发明涉及一种通过这种聚合抑制剂组合物来稳定乙烯基芳香族组合物以防止聚合的乙烯基芳香族组合物，以及一种稳定乙烯基芳香族组合物以防止聚合的方法，该方法包括加入有效量的这种聚合抑制剂组合物。
• Vinyl aromatic compositons stabilized against polymerization
  申请人：UNIROYAL CHEMICAL COMPANY, Inc.

  公开号：EP0334500A1

  公开（公告）日：1989-09-27

  Vinyl aromatic compounds are stabilized against polymerization by the addition of an effective amount of a polymerization inhibition composition comprising (a) a phenothiazine compound; and (b) an aryl-substituted phenylenediamine compound. In other aspects, this invention is directed to a vinyl aromatic composition stabilized against polymerization by such polymerication inhibitor composition, as well as to a method of stabilizing a vinyl aromatic composition against polymerization which method comprises adding an effective amount of such polymerization inhibitor composition.

  通过添加有效量的聚合抑制剂组合物来稳定乙烯基芳香族化合物以防止聚合，该组合物包括(a)吩噻嗪化合物；和(b)芳基取代的苯二胺化合物。在其他方面，本发明涉及一种通过这种聚合抑制剂组合物来稳定乙烯基芳香族组合物以防止聚合的乙烯基芳香族组合物，以及一种稳定乙烯基芳香族组合物以防止聚合的方法，该方法包括加入有效量的这种聚合抑制剂组合物。
• Polymerization inhibitors for acrylic acids and esters
  申请人：UNIROYAL CHEMICAL COMPANY, Inc.

  公开号：EP0522709A2

  公开（公告）日：1993-01-13

  This invention is directed to certain N,N'-dinitroso phenylenediamines useful as polymerization inhibitors for acrylic acids and esters thereof. Also disclosed are compositions containing such compounds, and methods for inhibiting polymerization using such compounds and compositions.

  本发明涉及某些用作丙烯酸及其酯类聚合抑制剂的 N,N'-二亚硝基苯二胺。本发明还公开了含有此类化合物的组合物，以及使用此类化合物和组合物抑制聚合的方法。
• Preparation of tert-butyl esters of aliphatic carboxylic acids
  申请人：BASF SE

  公开号：US10023520B2

  公开（公告）日：2018-07-17

  A process for continuously preparing the tert-butyl ester of an aliphatic C1-C4 carboxylic acid comprises: a) the reaction of an aliphatic C1-C4 carboxylic acid with isobutene in the presence of an acidic catalyst to give an esterification mixture (G1); b) the partial evaporation of the esterification mixture (G1), giving a liquid first high boiler phase (SPh1) comprising the acidic catalyst, and a first vapor (B1) comprising tert-butyl ester; c) the fractional condensation of the first vapor (B1) by partially condensing the first vapor (B1) at a first pressure and a first temperature and obtaining a first condensate (K1), partially condensing the uncondensed second vapor (B2) at a second pressure and a second temperature and obtaining a second condensate (K2), the first temperature being 0 to 45° C. below the condensation temperature of the tert-butyl ester at the first pressure and the second temperature being 45 to 80° C. below the condensation temperature of the tert-butyl ester at the second pressure, with the proviso that the second temperature is at least 5° C. below the first temperature; and d) the combination of the first condensate (K1) and the second condensate (K2) and the feeding to a combined workup, and recycling of the third vapor (B3) not condensed at the second temperature into step a). The process allows the preparation of the tert-butyl ester of an aliphatic C1-C4 carboxylic acid by reaction of the carboxylic acid with isobutene, with isolation of unconverted isobutene from the esterification mixture in an energetically favorable manner and with an improved degree of removal.

  一种连续制备脂肪族 C1-C4 羧酸叔丁酯的工艺包括a) 在酸性催化剂存在下，脂肪族 C1-C4 羧酸与异丁烯反应，生成酯化混合物 (G1)； b) 部分蒸发酯化混合物 (G1)，生成包含酸性催化剂的液态第一高锅炉相 (SPh1) 和包含叔丁酯的第一蒸汽 (B1)；c) 通过在第一压力和第一温度下部分冷凝第一蒸气 (B1) 并得到第一冷凝物 (K1)，在第二压力和第二温度下部分冷凝未冷凝的第二蒸气 (B2)并得到第二冷凝物 (K2)，第一温度为 0 至 45° C.第一温度低于叔丁酯在第一压力下的冷凝温度 0 至 45°C，第二温度低于叔丁酯在第二压力下的冷凝温度 45 至 80°C，但第二温度至少低于第一温度 5°C；以及 d) 将第一冷凝物（K1）和第二冷凝物（K2）合并，并送入合并工序，将未在第二温度下冷凝的第三蒸汽（B3）回收至步骤 a）。该工艺可以通过羧酸与异丁烯的反应制备脂肪族 C1-C4 羧酸的叔丁酯，并以能量有利的方式从酯化混合物中分离出未转化的异丁烯，同时提高了异丁烯的去除率。

表征谱图