4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 1,6,7,8,9,9a-hexahydro-4-oxo-, ethyl ester | 39080-62-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶并嘧啶类
• 英文名称: 4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 1,6,7,8,9,9a-hexahydro-4-oxo-, ethyl ester
• 英文别名: ethyl 4-oxo-1,6,7,8,9,9a-hexahydropyrido[1,2-a]pyrimidine-3-carboxylate
• CAS: 39080-62-1
• 化学式: C₁₁H₁₆N₂O₃
• 分子量: 224.26
• InChiKey: SVKDPZQTITZACV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  58.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Gilsonite derived pharmaceutical delivery compositions and methods: nail applications
  申请人：Scarampi Sebastiano

  公开号：US20060008432A1

  公开（公告）日：2006-01-12

  Pharmaceutical formulations comprising Gilsonite oil for topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil.

  本发明公开了由 Gilsonite 油组成的用于局部或透皮应用的药物制剂。此外，还提供了透皮施用具有增强渗透性的生物活性剂的方法，其中包括局部施用包含透皮有效量 Gilsonite 油的组合物。
• Gilsonite derived pharmaceutical delivery compositions and methods: cosmetic applications
  申请人：Scarampi Sebastiano

  公开号：US20060008516A1

  公开（公告）日：2006-01-12

  Pharmaceutical formulations comprising Gilsonite oil for topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil.

  本发明公开了由 Gilsonite 油组成的用于局部或透皮应用的药物制剂。此外，还提供了透皮施用具有增强渗透性的生物活性剂的方法，其中包括局部施用包含透皮有效量 Gilsonite 油的组合物。
• GILSONITE DERIVED PHARMACEUTICAL DELIVERY COMPOSITIONS AND METHODS : COSMETIC AND NAIL APPLICATIONS
  申请人：DPC Products, Inc.

  公开号：EP1778172A1

  公开（公告）日：2007-05-02
• [EN] GILSONITE DERIVED PHARMACEUTICAL DELIVERY COMPOSITIONS AND METHODS : COSMETIC AND NAIL APPLICATIONS<br/>[FR] COMPOSITIONS DÉRIVÉES DE GILSONITE DE RELARGAGE D'UN PRODUIT PHARMACEUTIQUE ET PROCÉDÉS D'UTILISATION DE CELLES-CI : APPLICATIONS COSMÉTIQUES ET AUX ONGLES
  申请人：DPC PRODUCTS INC

  公开号：WO2006014545A1

  公开（公告）日：2006-02-09

  Pharmaceutical formulations comprising Gilsonite oil topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil.