2-Methoxytetrahydropyran | 931-60-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2-Methoxytetrahydropyran
• 英文别名: (2R)-2-methoxyoxane
• CAS: 931-60-2
• 化学式: C₆H₁₂O₂
• 分子量: 116.16
• InChiKey: XTDKZSUYCXHXJM-ZCFIWIBFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Perivascular wraps
  申请人：Gravett M David

  公开号：US20080085855A1

  公开（公告）日：2008-04-10

  The present invention provides compositions, devices, and methods for maintaining or improving the integrity of body passageways following surgery, such as at a graft site, or injury. Delivery devices including one or more therapeutic agents and a mesh are described. Representative examples of therapeutic agents include microtubule stabilizing agents, anti-angiogenic factors, inhibitors of smooth muscle cell growth or proliferation, non-steroidal anti-inflammatory drugs, and other factors useful preventing and/or reducing a proliferative biological response that may obstruct or hinder the optimal functioning of the passageway or cavity.

  本发明提供了维持或改善手术后身体通道完整性的组合物、装置和方法，例如在移植部位或受伤处。描述了包括一个或多个治疗剂和网状物的输送装置。治疗剂的代表性例子包括微管稳定剂、抗血管生成因子、平滑肌细胞生长或增殖抑制剂、非甾体抗炎药和其他有用的因子，用于预防和/或减少可能阻碍或妨碍通道或腔体的最佳功能的增殖生物反应。
• Compositions and methods for coating medical implants
  申请人：ANGIOTECH INTERNATIONAL AG

  公开号：EP2075014A2

  公开（公告）日：2009-07-01

  Medical implants are provided which release an anthracycline, flouropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.

  医用植入物可释放蒽环类、氟嘧啶类、叶酸拮抗剂、荚膜毒素、喜树碱、羟基脲和/或铂复合物，从而抑制或降低与植入物相关的感染发生率。
• Soft tissue implants and drug combination compositions, and use thereof
  申请人：Hunter L. William

  公开号：US20070196421A1

  公开（公告）日：2007-08-23

  Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring drug combination in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
• Anti-scarring drug combinations and use thereof
  申请人：Hunter L. William

  公开号：US20070208134A1

  公开（公告）日：2007-09-06

  The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
• Implantable sensors, implantable pumps and anti-scarring drug combinations
  申请人：Hunter L. William

  公开号：US20070197957A1

  公开（公告）日：2007-08-23

  Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent or a composition that comprises an anti-scarring agent to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.