5-(phenylamino)oct-7-en-1-ol | 1270174-21-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 5-(phenylamino)oct-7-en-1-ol
• 英文别名: 5-Anilinooct-7-en-1-ol；5-anilinooct-7-en-1-ol
• CAS: 1270174-21-4
• 化学式: C₁₄H₂₁NO
• 分子量: 219.327
• InChiKey: MNRNJFOZZYKKQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯胺 在 三乙基硼 、 三丁基膦 、 palladium diacetate 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 24.5h， 生成 5-(phenylamino)oct-7-en-1-ol
  参考文献：
  名称：

  Nucleophilic allylation of N,O-acetals with allylic alcohols promoted by Pd/Et3B and Pd/Et2Zn systems

  摘要：

  Pd/Et3B and Pd/Et2Zn systems promote the nucleophilic allylations of 2-aminotetrahydrofuran and 2-aminotetrahydropyran with allylic alcohols to provide omega-hydroxyhomoallylamines in high yields. The transformation is applicable to the allylation of non-protective carbohydrates, such as ribose and deoxyribose. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.12.064

文献信息

• Nucleophilic allylation of N,O-acetals with allylic alcohols promoted by Pd/Et3B and Pd/Et2Zn systems
  作者：Yumi Yamaguchi、Mariko Hashimoto、Katsumi Tohyama、Masanari Kimura

  DOI：10.1016/j.tetlet.2010.12.064

  日期：2011.2

  Pd/Et3B and Pd/Et2Zn systems promote the nucleophilic allylations of 2-aminotetrahydrofuran and 2-aminotetrahydropyran with allylic alcohols to provide omega-hydroxyhomoallylamines in high yields. The transformation is applicable to the allylation of non-protective carbohydrates, such as ribose and deoxyribose. (C) 2010 Elsevier Ltd. All rights reserved.