2-Imino-10-methyl-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide | 618410-57-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶并嘧啶类
• 英文名称: 2-Imino-10-methyl-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
• 英文别名: 6-imino-11-methyl-2-oxo-7-(pyridin-3-ylmethyl)-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
• CAS: 618410-57-4
• 化学式: C₁₉H₁₆N₆O₂
• mdl: MFCD03509707
• 分子量: 360.4
• InChiKey: PQNQSRSERFJOKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  116
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof
  申请人：Alevere Medical Corporation

  公开号：US10888563B2

  公开（公告）日：2021-01-12

  The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.

  本发明提供了融合杂环有机化合物（如二氢吡唑并哒嗪酮）、含有此类化合物的组合物、医药包以及使用此类化合物和组合物塑身和/或减少受试者脂肪的方法。
• FUSED HETEROTRICYCLIC ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
  申请人：Alevere Medical Corporation

  公开号：US20160339029A1

  公开（公告）日：2016-11-24

  The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.
• [EN] FUSED HETEROCYCLIC ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF<br/>[FR] COMPOSÉS ORGANIQUES HÉTÉROCYCLIQUES FUSIONNÉS, COMPOSITIONS PHARMACEUTIQUES ET UTILISATIONS MÉDICALES ASSOCIÉES
  申请人：ALEVERE MEDICAL CORP

  公开号：WO2015061280A1

  公开（公告）日：2015-04-30

  The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.