2-[3-[2-(3-Methoxyanilino)-1,3-thiazol-4-yl]phenyl]isoindole-1,3-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-[3-[2-(3-Methoxyanilino)-1,3-thiazol-4-yl]phenyl]isoindole-1,3-dione
• 化学式: C₂₄H₁₇N₃O₃S
• mdl: MFCD00748078
• 分子量: 427.5
• InChiKey: ZTAAHOUARHTYJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  99.8
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] NEW METHIONINE METABOLIC PATHWAY INHIBITORS<br/>[FR] NOUVEAUX INHIBITEURS DE LA VOIE MÉTABOLIQUE DE MÉTHIONINE
  申请人：GAVISH GALILEE BIO APPL LTD

  公开号：WO2019142192A1

  公开（公告）日：2019-07-25

  Novel compounds capable of inhibiting methionine metabolic pathway are provided. These compounds are used in inhibiting cystathionin γ-synthase (CGS) in general, and in plants, fungi and bacteria, in particular. These compounds of the invention are used as herbicides, pesticides, fungicides, agricultural plant stimulants or antimicrobial agents. The compounds of the present invention can be used for seed treatment. In particular, the compounds of the invention are used as selective herbicides, non-selective herbicides, agricultural herbicides, non-agricultural herbicides or weed killers, herbicides in integrated pest management, herbicides in gardening, herbicides in clearing waste ground, herbicides in clearing industrial or constructions sites, or herbicides in clearing railways and railway embankments.

  本发明提供了一种能够抑制蛋氨酸代谢途径的新化合物。这些化合物通常用于抑制半胱氨酸γ-合成酶（CGS），尤其是在植物、真菌和细菌中。本发明的这些化合物可用作除草剂、杀虫剂、杀菌剂、农业植物刺激剂或抗微生物剂。本发明的化合物可用于种子处理。特别地，本发明的化合物可用作选择性除草剂、非选择性除草剂、农业除草剂、非农业除草剂或除草剂、综合害虫管理中的除草剂、园艺中的除草剂、清理废地中的除草剂、清理工业或建筑工地中的除草剂，或清理铁路和铁路路基中的除草剂。
• METHIONINE METABOLIC PATHWAY INHIBITORS
  申请人：GAVISH-GALILEE BIO APPLICATIONS LTD.

  公开号：US20200331872A1

  公开（公告）日：2020-10-22

  The present invention provides novel inhibitors of cystathionin gamma synthase (CGS), their use as selective and non-selective herbicides, agricultural and non-agricultural herbicides, herbicides in integrated pest management, herbicides for gardening, clearing waste ground, clearing industrial or constructions sites, clearing railways and railway embankments, pesticide, fungicide, agricultural plant stimulant or antimicrobial agent. Also provided is a method for the control of undesired vegetation or clearing areas from the undesired vegetation comprising applying to the locus of said undesired vegetation, to the undesired plants or to a habitat thereof, a herbicidally effective amount of the compound of the present invention.