肉豆蔻醇硫酸酯DEA盐 | 65104-61-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 肉豆蔻醇硫酸酯DEA盐
• 英文名称: Bis(2-hydroxyethyl)azanium;tetradecyl sulfate
• CAS: 65104-61-2
• 化学式: C18H41NO6S
• 分子量: 399.6
• InChiKey: QZUFUZCFYQJWBG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.07
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  125
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• POLYORGANOSILOXANE EMULSION, PROCESS FOR PRODUCING THE SAME, AND MATERIAL FOR COSMETIC PREPARATION
  申请人：Dow Corning Toray Silicone Co., Ltd.

  公开号：EP1394215A1

  公开（公告）日：2004-03-03

  A polyorganosiloxane emulsion comprising (A) polyorganosiloxane, (B) N-acylalkyltaurine and/or a salt thereof, and (C) water, the aforementioned emulsion having an average particle diameter of 0.15 µm or more; a method of preparation of the polyorganosiloxane emulsion, characterized by subjecting a polyorganosiloxane (a) having a molecular weight lower than that of component (A), to emulsification polymerization in water in the presence of (B) N-acylalkyltaurine and/or a salt thereof; and a cosmetic raw material comprising the aforementioned polyorganosiloxane emulsion. The cosmetic raw material of the invention possesses excellent cosmetic functionalities such as wettability, smoothness, and good affinity to skin and hair. Furthermore, it is characterized by good stability in storage and compounding stability in combination with our cosmetic raw materials.

  一种聚有机硅氧烷乳液，包括(A)聚有机硅氧烷，(B)N-酰基烷基牛磺酸和/或其盐，和(C)水，上述乳液的平均颗粒直径为0.15 µm 或以上；一种聚有机硅氧烷乳液的制备方法，其特征在于将分子量低于组分(A)的聚有机硅氧烷(a)在(B)N-酰基烷基嘌呤和/或其盐存在下在水中进行乳化聚合；以及一种包含上述聚有机硅氧烷乳液的化妆品原料。本发明的化妆品原料具有出色的化妆品功能，如润湿性、平滑性以及与皮肤和头发的良好亲和性。此外，它还具有良好的贮存稳定性，以及与我们的化妆品原料配合使用时的复配稳定性。
• AQUEOUS SUSPENSION OF CROSSLINKED SILICONE PARTICLES, AQUEOUS EMULSION OF OIL CONTAINING CROSSLINKED SILICONE PARTICLES, AND COSMETIC INGREDIENTS
  申请人：Dow Corning Toray Silicone Company, Ltd.

  公开号：EP1541633A1

  公开（公告）日：2005-06-15

  Aqueous suspensions of cross-linked silicone particles comprising : (A) cross-linked silicone particles with an average particle size of from 0.1 to 500 µm, (B) N-acyl-, N-hydrocarbon taurines and/or their salts, and (C) water, aqueous emulsions of oil containing cross-linked silicone particles comprising : (A) cross-linked silicone particles with an average particle size of from 0.1 to 500 µm, (D) oil, (B) N-acyl-, N-hydrocarbon taurines and/or their salts, and (C) water, with component (A) contained in droplets of component (D) dispersed in water, and cosmetic raw materials comprising said aqueous suspensions or said aqueous emulsions. The suspensions and emulsions are characterized by superior stability and by low environmental impact and minimal effects on the human body. In addition, they are extremely useful as cosmetic raw materials because of their superior cosmetics functionality such as wetness and smoothness.

  交联有机硅颗粒的水悬浮液，包括：(A)平均粒径为 0.1 至 500 微米的交联有机硅颗粒，(B)N-酰基-、N-烃基牛磺酸和/或其盐，以及(C)水；含有交联有机硅颗粒的油的水乳液，包括：(A)平均粒径为 0.1至500微米的交联有机硅颗粒，(D)油，(B)N-酰基、N-烃基牛磺酸和/或其盐，以及(C)水，其中组分(A)包含在分散于水中的组分(D)的液滴中，以及包含所述水性悬浮液或所述水性乳液的化妆品原料。这些悬浮液和乳液具有优异的稳定性，对环境的影响较小，对人体的影响也最小。此外，它们作为化妆品原料也非常有用，因为它们具有卓越的化妆品功能，如润湿性和柔滑性。
• Silicone Microemulsion Composition
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2514405A1

  公开（公告）日：2012-10-24

  A silicone microemulsion composition obtained by microemulsifying a carboxy-modified organopolysiloxane, and having a lower surface tension than conventional microemulsions. The composition includes 100 parts by mass of a specific carboxy-modified organopolysiloxane (A), 25 to 75 parts by mass of a specific polyether-modified organopolysiloxane (B), 0.1 to 10 parts by mass of an anionic surfactant, and 20 to 6,000 parts by mass of water, wherein the average particle size of the emulsion particles is not more than 100 nm.

  一种通过微乳化羧基改性有机聚硅氧烷获得的硅氧烷微乳液组合物，其表面张力低于传统微乳液。 该组合物包括 100 份（质量份）特定的羧基改性有机聚硅氧烷（A）、25 至 75 份（质量份）特定的聚醚改性有机聚硅氧烷（B）、0.1 至 10 份（质量份）阴离子表面活性剂和 20 至 6000 份（质量份）水，其中乳液颗粒的平均粒径不超过 100 纳米。
• Omega-3 fatty acid ester compositions
  申请人：Sancilio & Company, Inc.

  公开号：US10287528B2

  公开（公告）日：2019-05-14

  Compositions including at least one Omega-3 fatty acid ester and at least one surface active agent are provided; wherein the compositions form micelles when in contact with an aqueous medium. Also provided is a method of administering to a subject such a composition, wherein the at least one Omega-3 fatty acid ester forms micelles when in contact with an aqueous medium, and the bioavailability of the at least one Omega-3 fatty acid ester is substantially independent of a food effect. The compositions are useful for treating cardiovascular conditions or disorders in a subject and for reducing side effects associated with the ingestion of Omega-3 fatty acid esters. Further provided are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions on how to administer the compositions.

  提供了包括至少一种Omega-3脂肪酸酯和至少一种表面活性剂的组合物；其中组合物在与水介质接触时形成胶束。还提供了一种向受试者施用这种组合物的方法，其中至少一种 Omega-3 脂肪酸酯在与水介质接触时形成胶束，并且至少一种 Omega-3 脂肪酸酯的生物利用度基本上不受食物影响。这些组合物可用于治疗受试者的心血管疾病或失调，并减少与摄入 Omega-3 脂肪酸酯相关的副作用。此外，还提供了用于施用组合物的各种剂型以及组合物在功能性食品中的用途。本文还提供了附有如何施用组合物说明的试剂盒。
• Sickle cell disease treatment utilizing omega-3 fatty acids
  申请人：Micelle BioPharma, Inc.

  公开号：US10894027B2

  公开（公告）日：2021-01-19

  Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect. The compositions are useful for treating certain disease states which may include (1) malabsorption syndromes, (2) primary sclerosing cholangitis (PSC), (3) non-alcoholic fatty liver disease (NAFLD), (4) sickle cell disease (SCD), (5) age-related macular degeneration (AMD), and (6) neurodegenerative disease, including, Parkinson's Disease (PD), Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Epilepsy, Bi-polar Syndrome, traumatic brain injury, peripheral neuropathy, and Multiple Sclerosis (MS). Described are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions for their administration.

  本文描述了包括至少一种欧米伽-3 脂肪酸（甘油三酯、酯或游离脂肪酸酯形式）和至少一种表面活性剂的组合物；其中组合物在与水介质接触时形成胶束。还提供了向受试者施用包括至少一种欧米伽-3 脂肪酸（甘油三酯、酯或游离脂肪酸酯形式）和至少一种表面活性剂的组合物的方法，其中组合物在与水介质接触时形成胶束，且欧米伽-3 脂肪酸的生物利用度基本上不受食物影响。这些组合物可用于治疗某些疾病，包括：（1）吸收不良综合征；（2）原发性硬化性胆管炎（PSC）；（3）非酒精性脂肪肝（NAFLD）；（4）镰状细胞病（SCD）；（5）老年性黄斑变性（AMD）；以及（6）神经退行性疾病、和 (6) 神经退行性疾病，包括帕金森病 (PD)、阿尔茨海默病 (AD)、肌萎缩侧索硬化症 (ALS 或卢伽雷氏病)、癫痫、双极综合征、脑外伤、周围神经病变和多发性硬化症 (MS)。本文还描述了施用组合物的各种剂型以及组合物在功能性食品中的用途。本文还提供了附有使用说明的试剂盒。