4'-amino-N-phenyl-(5-fluoro)-2,3-naphtalic imide | 1251927-61-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4'-amino-N-phenyl-(5-fluoro)-2,3-naphtalic imide
• 英文别名: 5-fluoro-N-(4'-methoxyphenyl)-2,3-naphthalimide；5-Fluoro-2-(4-methoxyphenyl)benzo[f]isoindole-1,3-dione；5-fluoro-2-(4-methoxyphenyl)benzo[f]isoindole-1,3-dione
• CAS: 1251927-61-3
• 化学式: C₁₉H₁₂FNO₃
• 分子量: 321.308
• InChiKey: VMDPGIWFYNBVTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-fluoro-2,3-naphthalic anhydride 、 甲氧苯胺 在 吡啶 作用下， 反应 12.0h， 生成 4'-amino-N-phenyl-(5-fluoro)-2,3-naphtalic imide
  参考文献：
  名称：

  Dual Fluorescent N-Aryl-2,3- naphthalimides: Applications in Ratiometric DNA Detection and White Organic Light-Emitting Devices

  摘要：

  A ten element matrix of 5- and 6-substituted-(2,3)-naphthalimides was prepared for the appropriate placement of substituents necessary to promote dual fluorescence (DF). As prescribed by our balanced seesaw photophysical model this matrix yielded nine new DF dyes out of a possible ten compounds. From this set of nine DF dyes, 4-fluoronaphthalic amide (37) was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.

  DOI：

  10.1021/ol101760m

文献信息

• Dual Fluorescent <i>N</i>-Aryl-2,3- naphthalimides: Applications in Ratiometric DNA Detection and White Organic Light-Emitting Devices
  作者：Premchendar Nandhikonda、Michael D. Heagy

  DOI：10.1021/ol101760m

  日期：2010.11.5

  A ten element matrix of 5- and 6-substituted-(2,3)-naphthalimides was prepared for the appropriate placement of substituents necessary to promote dual fluorescence (DF). As prescribed by our balanced seesaw photophysical model this matrix yielded nine new DF dyes out of a possible ten compounds. From this set of nine DF dyes, 4-fluoronaphthalic amide (37) was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.