2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 2-{[4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one
• 英文别名: 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenothiazin-10-ylethanone
• 化学式: C₂₂H₁₈N₄O₂S₂
• mdl: MFCD04210733
• 分子量: 434.5
• InChiKey: ASZRHXKUEMHBKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.136
• 拓扑面积：
  115
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• [EN] THERMAL VOLATILIZATION OF ORCO AGONISTS<br/>[FR] VOLATILISATION THERMIQUE D'AGONISTES D'ORCO
  申请人：ZWIEBEL LAURENCE J

  公开号：WO2017011466A1

  公开（公告）日：2017-01-19

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  在一个方面，该发明涉及昆虫嗅觉受体的化学调节剂。具体来说，提供了可以抑制空气中蚊子等昆虫的感觉（例如宿主定位）功能的化合物和组合物。还提供了使用这些药剂的方法以及包含相同药剂的文章。本摘要旨在作为在特定领域搜索的扫描工具，并不打算限制本发明。
• Compositions for inhibition of insect sensing
  申请人：Vanderbilt University

  公开号：US10188105B2

  公开（公告）日：2019-01-29

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitoes. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  一方面，本发明涉及昆虫嗅觉受体的化学调节剂。特别是，本发明提供了可抑制蚊子等空气传播昆虫的感官（如宿主靶向）功能的化合物和组合物。此外，还提供了使用此类制剂的方法以及含有此类制剂的物品。本摘要旨在作为一种扫描工具，用于特定技术领域的搜索，而非对本发明的限制。
• THERMAL VOLATILIZATION OF ORCO AGONISTS
  申请人：VANDERBILT UNIVERSITY

  公开号：US20180192651A1

  公开（公告）日：2018-07-12

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• Compositions for Inhibition of Insect Sensing
  申请人：Vanderbilt University

  公开号：US20190075798A1

  公开（公告）日：2019-03-14

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitoes. Methods of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US9578881B2
  申请人：——

  公开号：US9578881B2

  公开（公告）日：2017-02-28