5-氨基异吲唑 | 64309-76-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 中文名称: 5-氨基异吲唑
• 中文别名: 5-氨基吲唑盐酸盐
• 英文名称: 5-Aminoindazole hydrochloride
• 英文别名: 1H-indazol-5-amine;hydrochloride
• CAS: 64309-76-8
• 化学式: C7H8ClN3
• mdl: MFCD06801367
• 分子量: 169.61
• InChiKey: DHDNJTBILGPMBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.47
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.7
• 氢给体数：
  3
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

制备方法与用途

类别：有毒物品

可燃性危险特性：

• 可燃；燃烧时产生有毒的氮氧化物和氯化氢烟雾

储运特性：

• 应存放在通风、低温、干燥的库房内

灭火剂：

• 干粉、泡沫、砂土、二氧化碳或雾状水均可用于灭火

文献信息

• Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands
  申请人：Laboratorios Del. Dr. Esteve, S.A.

  公开号：EP2116547A1

  公开（公告）日：2009-11-11

  The invention relates to compounds (I) having pharmacological activity towards the 5-HT6 receptor, and more particularly to some N-imidazo[2,1-b]thiazole-5-sulfonamide derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT6 is involved.

  该发明涉及具有对5-HT6受体具有药理活性的化合物(I)，更具体地涉及一些N-咪唑[2,1-b]噻唑酮-5-磺酰胺衍生物，以及制备这些化合物的方法，包括含有它们的药物组合物，以及它们用于治疗和/或预防涉及5-HT6的疾病。
• Substituted N-phenyl-2,3-dihydroimidazo[2,1-b]thiazole-5-sulfonamide derivatives as 5-HT6 ligands
  申请人：Laboratorios Del. Dr. Esteve, S.A.

  公开号：EP2116546A1

  公开（公告）日：2009-11-11

  The invention relates to compounds having pharmacological activity towards the 5-HT6 receptor, and more particularly to some N-phenyl-2,3-dihydroimidazo[2,1-b]thiazole-5-sulfonamide derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT6 is involved.

  该发明涉及具有对5-HT6受体具有药理活性的化合物，更特别地涉及一些N-苯基-2,3-二氢咪唑[2,1-b]噻唑-5-磺酰胺衍生物，以及制备这些化合物的方法，包括含有它们的药物组合物，以及它们用于治疗和/或预防5-HT6参与的疾病。
• [EN] SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS<br/>[FR] DÉRIVÉS DE N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE SUBSTITUÉS UTILISÉS COMME LIGANDS DE 5-HT6
  申请人：ESTEVE LABOR DR

  公开号：WO2009135925A1

  公开（公告）日：2009-11-12

  The invention relates to compounds (I) having pharmacological activity towards the 5-HT6 receptor, and more particularly to some N-imidazo[2,1-b]thiazole-5-sulfonamide derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT6 is involved.
• [EN] SUBSTITUTED N-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS<br/>[FR] DÉRIVÉS DE N-PHÉNYL-2,3-DIHYDROIMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE SUBSTITUÉS UTILISÉS COMME LIGANDS DE 5-HT6
  申请人：ESTEVE LABOR DR

  公开号：WO2009135927A1

  公开（公告）日：2009-11-12

  The invention relates to compounds having pharmacological activity towards the 5-HT6 receptor, and more particularly to some N-phenyl-2,3-dihydroimidazo[2,1- b]thiazole-5 -sulfonamide derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT6 is involved.