4-cyclooctylphenol | 14109-16-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-cyclooctylphenol
• CAS: 14109-16-1
• 化学式: C₁₄H₂₀O
• 分子量: 204.312
• InChiKey: XRLTYAWTXOPOSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-cyclooctylphenol 生成 benzoic acid-(4-cyclooctyl-phenyl ester)
  参考文献：
  名称：

  847.环辛酸酯衍生物。第三部分 环辛基酚

  摘要：

  DOI：

  10.1039/jr9530004156
• 作为产物：
  描述：

  顺-环辛烯 、 苯酚 在 三氟化硼 作用下， 生成 4-cyclooctylphenol
  参考文献：
  名称：

  Podberezina,A.S.; Kheifits,L.A., Journal of Organic Chemistry USSR (English Translation), 1966, vol. 2, p. 2007 - 2009

  摘要：

  DOI：

文献信息

• [EN] 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS<br/>[FR] COMPOSES 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE POUR LE TRAITEMENT DE LA TUBERCULOSE
  申请人：OTSUKA PHARMA CO LTD

  公开号：WO2005042542A1

  公开（公告）日：2005-05-12

  The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula: (1)in the above formula (1), R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R1 and -(CH2)nR2 may form a spiro ring represented by the formula (30) below, together with the adjacent carbon atom (in the formula below, RRR represents a piperidyl group which may have substituents on the piperidine ring), (30)and R2 represents a benzothiazolyloxy group, quinolyloxy group, pyridyloxy group or the like. The present compound has an excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria.

  本发明提供了一种由以下一般式表示的2,3-二氢-6-硝基咪唑[2,1-b]噁唑化合物：(1)在上述式(1)中，R1代表氢原子或C1-C6烷基，n代表0至6的整数，R1和-(CH2)nR2可以与下面的式(30)一起形成一个螺环，与相邻的碳原子一起（在下面的式中，RRR代表可能在哌啶环上具有取代基的哌啶基），(30)和R2代表苯并噻唑氧基、喹啉氧基、吡啶氧基或类似物。该化合物对结核分枝杆菌、多药耐药结核分枝杆菌和非典型耐酸细菌具有出色的杀菌作用。
• 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis
  申请人：Tsubouchi Hidetsugu

  公开号：US20080119478A1

  公开（公告）日：2008-05-22

  The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula: (1) in the above formula (1), R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R1 and —(CH2) n R2 may form a spiro ring represented by the formula (30) below, together with the adjacent carbon atom (in the formula below, RRR represents a piperidyl group which may have substituents on the piperidine ring), (30) and R2 represents a benzothiazolyloxy group, quinolyloxy group, pyridyloxy group or the like. The present compound has an excellent bactericidal action against Mycobacterium tuberculosis , multi-drug-resistant Mycobacterium tuberculosis , and atypical acid-fast bacteria.

  本发明提供了一种由下述通式（1）表示的2,3-二氢-6-硝基咪唑[2,1-b]噁唑化合物： 在上述式（1）中，R1代表氢原子或C1-C6烷基，n代表0到6的整数，R1和—(CH2)nR2可以与相邻的碳原子形成如下式（30）所示的螺环，其中，在下式中，RRR代表可能在哌啶环上具有取代基的哌啶基： （30）且R2代表苯并噻唑氧基、喹啉氧基、吡啶氧基或类似基团。该化合物对结核分枝杆菌、多重耐药结核分枝杆菌和非典型酸杆菌具有优异的杀菌作用。
• POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF
  申请人：YAMAKAWA Yoshitaka

  公开号：US20120052412A1

  公开（公告）日：2012-03-01

  A polyarylene copolymer having a sulfonic acid group which has high proton conductivity and reduced swelling in hot water and reduced shrinkage in drying; a solid polymer electrolyte and a proton conductive membrane comprising the copolymer; and a membrane-electrode assembly using these. The polyarylene block copolymer comprises a polymer segment (A) having a sulfonic acid group, and a polymer segment (B) having substantially no sulfonic acid group, the polymer segment (B) having substantially no sulfonic acid group comprising a structural unit represented by the following formula (1).

  一种具有磺酸基的聚芳烃共聚物，具有高质子传导性能，在热水中具有减少肿胀和干燥中减少收缩的特性；包括该共聚物的固体聚合物电解质和质子导电膜；以及使用这些的膜电极组件。该聚芳烃嵌段共聚物包括具有磺酸基的聚合物段（A）和基本上没有磺酸基的聚合物段（B），基本上没有磺酸基的聚合物段（B）包括由以下公式（1）表示的结构单元。
• (Hydrocarbylthio)phenols and their preparation
  申请人：ETHYL CORPORATION

  公开号：EP0122203A1

  公开（公告）日：1984-10-17

  (Hydrocarbylthio)phenols containing at leasttwo hydrocarbylthio groups or hydrocarbylthio groups in either or both of the meta positions, relative to the hydroxy group, on a phenolic ring are prepared by reacting phenolic compounds with an excess of hydrocarbyl disulfide in the presence of catalytic amounts of an aluminium phenoxide. Novel and useful (hydrocarbylthio)phenols containing at least two hydrocarbylthio groups or hydrocarbylthio groups in either of both of the meta positions, relative to the hydroxy group, on a phenolic ring can be prepared by this process. (Hydrocarbylthio)phenols containing at least two hydrocarbylthio groups or hydrocarbylthio groups in either of both of the meta positions, relative to the hydroxy group, on a phenolic ring are effective antioxidants for organic material normally susceptible to oxidative deterioration, such as mineral oil.

  (相对于羟基而言，在酚环的任一或两个元位置上至少含有两个烃硫基或烃硫基的（烃硫基）酚，是通过在催化量的苯氧化铝存在下，使酚类化合物与过量的二硫化烃反应制备的。通过这种方法可以制备出新的有用的（烃基硫基）酚，这些酚至少含有两个烃基硫基，或者烃基硫基位于酚环上相对于羟基的两个元位置中的一个。(在酚醛环上相对于羟基的两个元位置中的任一位置上含有至少两个烃硫基或烃硫基的（烃硫基）苯酚是通常易氧化变质的有机材料（如矿物油）的有效抗氧化剂。
• Polyarylene block copolymer having sulfonic acid group and use thereof
  申请人：JSR Corporation

  公开号：EP2424018A1

  公开（公告）日：2012-02-29

  A polyarylene copolymer having a sulfonic acid group which has high proton conductivity and reduced swelling in hot water and reduced shrinkage in drying; a solid polymer electrolyte and a proton conductive membrane comprising the copolymer; and a membrane-electrode assembly using these. The polyarylene block copolymer comprises a polymer segment (A) having a sulfonic acid group, and a polymer segment (B) having substantially no sulfonic acid group, the polymer segment (B) having substantially no sulfonic acid group comprising a structural unit represented by the following formula (1).

  一种具有磺酸基团的聚芳基醚共聚物，它具有高质子传导性，在热水中溶胀减小，在干燥中收缩减小；一种固体聚合物电解质和一种质子传导膜，由该共聚物组成；以及一种使用这些共聚物的膜电极组件。 聚芳基嵌段共聚物包括具有磺酸基的聚合物段（A）和基本上没有磺酸基的聚合物段（B），基本上没有磺酸基的聚合物段（B）由下式（1）表示的结构单元组成。