1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-propanoyloxolan-2-yl]pyrimidine-2,4-dione

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: 1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-propanoyloxolan-2-yl]pyrimidine-2,4-dione
• 化学式: C₁₂H₁₆N₂O₇
• 分子量: 300.26
• InChiKey: HMTUWGXIQRRCMG-XYHAGOFUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• USE OF COMPOUNDS FOR THE TREATMENT OF PAIN
  申请人：Akron Molecules AG

  公开号：EP2846788A1

  公开（公告）日：2015-03-18
• [EN] USE OF COMPOUNDS FOR THE TREATMENT OF PAIN<br/>[FR] UTILISATION DE COMPOSÉS POUR LE TRAITEMENT DE LA DOULEUR
  申请人：AKRON MOLECULES GMBH

  公开号：WO2013167743A1

  公开（公告）日：2013-11-14

  The present invention relates to new therapies to treat pain and related diseases, as well as pharmaceutical compounds for use in said therapies.
• [EN] BIOMEDICAL DEVICE IMPLANTABLE IN BONE AND/OR CARTILAGINOUS TISSUE, AND CORRESPONDING METHOD TO MANUFACTURE SAID BIOMEDICAL DEVICE<br/>[FR] DISPOSITIF BIOMÉDICAL IMPLANTABLE DANS L'OS ET/OU LE TISSU CARTILAGINEUX, ET PROCÉDÉ CORRESPONDANT POUR FABRIQUER LEDIT DISPOSITIF BIOMÉDICAL
  申请人：GALLI CARLO

  公开号：WO2014128289A1

  公开（公告）日：2014-08-28

  Aptamers for use in coating biomaterials, in particular for example for making biomedical devices which can be implanted in tissue, or tissue implants, corresponding method for coating biomaterials using aptamers and method for making biomedical devices which can be implanted in tissue, or tissue implants.