2-naphthoic acid 4-biphenylylamide | 135311-03-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-naphthoic acid 4-biphenylylamide
• 英文别名: N-(4-phenylphenyl)naphthalene-2-carboxamide
• CAS: 135311-03-4
• 化学式: C₂₃H₁₇NO
• 分子量: 323.394
• InChiKey: XVMYJLSGHPKHOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-萘甲酸 在 N-甲基吗啉 作用下， 以 四氢呋喃 为溶剂， 反应 1.05h， 生成 2-naphthoic acid 4-biphenylylamide
  参考文献：
  名称：

  Peptide conformational distributions as studied by electron-transfer kinetics

  摘要：

  The preparation and electron-transfer (ET) behavior of a homologous series of alanine oligomers bearing naphthoyl groups at the N-termini and biphenylylamide groups at the C-termini is described. Electron pulse radiolysis was used to generate the corresponding radical anions, and the rates of ET were monitored at 700 nm (decay of donor) and at 500 nm (growth of acceptor). Several systems displayed ET decays too fast to measure (k(et) > 10(10)), and in the others multiexponential decay kinetics were observed. The ET decay of dipeptide 3 could be fit to two exponential described by rate constants of 5.2 x 10(8) (22%) and 5.6 x 10(9) s-1 (78%). In the longer peptides, the fit of the rate constants (and their relative contributions to total intensity) becomes less well-defined, suggesting additional conformational diversity.

  DOI：

  10.1021/jo00018a034